Press release
Cytokine Release Syndrome Market to Show Remarkable Growth Trends from 2024 to 2034, DelveInsight Reports | Incyte, Kite, A Gilead Company, Jazz Pharmaceuticals
The Cytokine Release Syndrome market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Cytokine Release Syndrome pipeline products will significantly revolutionize the Cytokine Release Syndrome market dynamics.DelveInsight's "Cytokine Release Syndrome Market Insights, Epidemiology, and Market Forecast-2034′′ report offers an in-depth understanding of the Cytokine Release Syndrome, historical and forecasted epidemiology as well as the Cytokine Release Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
The Cytokine Release Syndrome market report covers emerging drugs, current treatment practices, market share of the individual therapies, and current & forecasted market size from 2020 to 2034. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
To Know in detail about the Cytokine Release Syndrome market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Cytokine Release Syndrome Market Insights
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Some of the key facts of the Cytokine Release Syndrome Market Report:
• The Cytokine Release Syndrome market size is anticipated to grow with a significant CAGR during the study period (2020-2034)
• In April 2025, CytoAgents Inc., a clinical-stage biotech company developing CTO1681 for the prevention and treatment of Cytokine Release Syndrome (CRS), has announced the successful completion of the initial dose and dose-limiting toxicity observation period in its ongoing Phase 1b/2a trial. Based on the evaluation of safety and efficacy data, the Safety Review Committee (SRC) has approved advancing to the next higher planned dose in Cohort 2.
• In October 2023, CytoAgents commenced enrollment for a Phase Ib/IIa clinical trial evaluating CTO1681 for cytokine release syndrome (CRS) treatment in lymphoma patients undergoing CAR T-cell Therapy. The trial, conducted at multiple US locations, begins with enrollment at UPMC Hillman Cancer Center. It aims to evaluate various doses of CTO1681 for efficacy, tolerability, and safety.
• The United States holds the dominant market share (85%) in the cytokine release syndrome market, surpassing EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.
• Presently, several companies have commenced clinical trials to explore novel treatment avenues. Major players like Incyte Corporation (Itacitinib) and Sobi Pharma (KINERET), among others, are investigating their respective candidates for the management of cytokine release syndrome (CRS) across the 7MM.
• The cytokine release syndrome market is predominantly led by the United States, which holds an 85% market share, surpassing that of the EU4 countries (Germany, Spain, Italy, France), the United Kingdom, and Japan.
• In 2023, DelveInsight estimated that cases of CRS in the United States made up approximately 30% of the total incidence across the seven major markets (7MM).
• According to DelveInsight's consultant estimates, around 30% of all CRS cases in the United States in 2023 were attributed to treatment with CAR-T therapies.
• Based on grade-specific incidence, Grade 3-4 cases made up about 18% of all incident CRS cases across the seven major markets (7MM) in 2023.
• The market size of Cytokine Release Syndrome was valued at USD 4.3 Million in 2021.
• Key Cytokine Release Syndrome Companies: Genentech, Swedish Orphan Biovitrum (sobi), Incyte, Kite, A Gilead Company, Jazz Pharmaceuticals, Fred Hutchinson Cancer Center, Ontario Clinical Oncology Group, GlaxoSmithKline, UNC Lineberger Comprehensive Cancer Center, SCRI Development Innovations and others
• Key Cytokine Release Syndrome Therapies: ACTEMRA/ROACTEMRA (tocilizumab), KINERET (anakinra), Itacitinib, Anakinra & Axicabtagene Ciloleucel, Defibrotide, Anakinra, Elranatamab injection, Otelixizumab, iC9-CAR19 cells, Teclistamab and others
Cytokine Release Syndrome Overview
Cytokine release syndrome (CRS) is a systemic inflammatory response that can occur as a result of certain medical treatments, particularly immunotherapies and cell-based therapies like CAR-T cell therapy. During these treatments, immune cells are activated and release large amounts of cytokines, which are signaling molecules that regulate the immune system. In CRS, this immune response becomes dysregulated, leading to an excessive release of cytokines into the bloodstream.
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Cytokine Release Syndrome Market
The dynamics of the Cytokine Release Syndrome market are anticipated to change in the coming years owing to the expected launch of emerging therapies and others during the forecasted period 2020-2034.
"As immunotherapies become translated into the clinical setting, a balance between efficacy and toxicity management must be achieved. Tremendous efforts have been put forward to use synthetic engineering of T-cells, including SUPRA CAR T-cells, synNotch receptors, and CRISP Rediting to enhance efficacy and off-the-shelf product feasibility."
Cytokine Release Syndrome Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.
Cytokine Release Syndrome Epidemiology Segmentation:
The Cytokine Release Syndrome market report proffers epidemiological analysis for the study period 2020-2034 in the 7MM segmented into:
• Total Prevalence of Cytokine Release Syndrome
• Prevalent Cases of Cytokine Release Syndrome by severity
• Gender-specific Prevalence of Cytokine Release Syndrome
• Diagnosed Cases of Episodic and Chronic Cytokine Release Syndrome
Download the report to understand which factors are driving Cytokine Release Syndrome epidemiology trends @ Cytokine Release Syndrome Epidemiological Insights
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Cytokine Release Syndrome Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Cytokine Release Syndrome market or expected to get launched during the study period. The analysis covers Cytokine Release Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Cytokine Release Syndrome Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
To know more about Cytokine Release Syndrome treatment, visit @ Cytokine Release Syndrome Medications
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Cytokine Release Syndrome Therapies and Key Companies
• ACTEMRA/ROACTEMRA (tocilizumab): Genentech
• KINERET (anakinra): Swedish Orphan Biovitrum (sobi)
• Itacitinib: Incyte
• Anakinra & Axicabtagene Ciloleucel: Kite, A Gilead Company
• Defibrotide: Jazz Pharmaceuticals
• Anakinra: Fred Hutchinson Cancer Center
• Elranatamab injection: Ontario Clinical Oncology Group
• Otelixizumab: GlaxoSmithKline
• iC9-CAR19 cells: UNC Lineberger Comprehensive Cancer Center
• Teclistamab: SCRI Development Innovations
Cytokine Release Syndrome Market Drivers
• Increasing incidence of Acute cytokine release syndrome (CRS)
• Increasing R&D activities
• Non-competitive landscape
Cytokine Release Syndrome Market Barriers
• Lack of awareness about the disease
• Lack of disease understanding
• Misdiagnosis of Cytokine Release Syndrome
Scope of the Cytokine Release Syndrome Market Report
• Study Period: 2020-2034
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Cytokine Release Syndrome Companies: Genentech, Swedish Orphan Biovitrum (sobi), Incyte, Kite, A Gilead Company, Jazz Pharmaceuticals, Fred Hutchinson Cancer Center, Ontario Clinical Oncology Group, GlaxoSmithKline, UNC Lineberger Comprehensive Cancer Center, SCRI Development Innovations, and others
• Key Cytokine Release Syndrome Therapies: ACTEMRA/ROACTEMRA (tocilizumab), KINERET (anakinra), Itacitinib, Anakinra & Axicabtagene Ciloleucel, Defibrotide, Anakinra, Elranatamab injection, Otelixizumab, iC9-CAR19 cells, Teclistamab, and others
• Cytokine Release Syndrome Therapeutic Assessment: Cytokine Release Syndrome current marketed and Cytokine Release Syndrome emerging therapies
• Cytokine Release Syndrome Market Dynamics: Cytokine Release Syndrome market drivers and Cytokine Release Syndrome market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Cytokine Release Syndrome Unmet Needs, KOL's views, Analyst's views, Cytokine Release Syndrome Market Access and Reimbursement
Discover more about therapies set to grab major Cytokine Release Syndrome market share @ Cytokine Release Syndrome Treatment Landscape
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Table of Contents
1. Cytokine Release Syndrome Market Report Introduction
2. Executive Summary for Cytokine Release Syndrome
3. SWOT analysis of Cytokine Release Syndrome
4. Cytokine Release Syndrome Patient Share (%) Overview at a Glance
5. Cytokine Release Syndrome Market Overview at a Glance
6. Cytokine Release Syndrome Disease Background and Overview
7. Cytokine Release Syndrome Epidemiology and Patient Population
8. Country-Specific Patient Population of Cytokine Release Syndrome
9. Cytokine Release Syndrome Current Treatment and Medical Practices
10. Cytokine Release Syndrome Unmet Needs
11. Cytokine Release Syndrome Emerging Therapies
12. Cytokine Release Syndrome Market Outlook
13. Country-Wise Cytokine Release Syndrome Market Analysis (2020-2034)
14. Cytokine Release Syndrome Market Access and Reimbursement of Therapies
15. Cytokine Release Syndrome Market Drivers
16. Cytokine Release Syndrome Market Barriers
17. Cytokine Release Syndrome Appendix
18. Cytokine Release Syndrome Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight
Related Reports:
Cytokine Release Syndrome Pipeline https://www.delveinsight.com/report-store/cytokine-release-syndrome-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
"Cytokine Release Syndrome Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Cytokine Release Syndrome market. A detailed picture of the Cytokine Release Syndrome pipeline landscape is provided, which includes the disease overview and Cytokine Release Syndrome treatment guidelines.
Cytokine Release Syndrome Epidemiology https://www.delveinsight.com/report-store/cytokine-release-syndrome-epidemiology-forecast?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
DelveInsight's 'Cytokine Release Syndrome Epidemiology Forecast to 2032' report delivers an in-depth understanding of the disease, historical and forecasted Cytokine Release Syndrome epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
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About DelveInsight
DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.
It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.
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