Press release
Global Plasmapheresis Market to Reach USD 3,497 Million by 2035, Expanding 2.1X with USD 1,846.8 Million Absolute Opportunity at 7.8% CAGR
The global Plasmapheresis market is expected to reach USD 3,497 Million by 2035, up from USD 1,528 Million in 2024. During the forecast period (2025 to 2035), the industry is projected to expand at a CAGR of 7.8%. Over the span of next ten years, the industry is poised to grow 2.1X with absolute dollar opportunity of USD 1,846.8 Million.The global healthcare landscape is undergoing rapid transformation, driven by technological advancements and an increasing prevalence of chronic diseases. Among the myriad of innovations, plasmapheresis stands out as a life-saving procedure used in treating autoimmune diseases, neurological disorders, and hematologic conditions. According to a detailed market report by Fact.MR, the plasmapheresis market is witnessing significant momentum due to the rise in demand for plasma-derived therapies and increasing awareness about therapeutic apheresis procedures.Market Overview
Plasmapheresis, also known as therapeutic plasma exchange, is a medical process in which plasma is separated from blood cells. This technique is employed to treat a variety of diseases by removing harmful antibodies, toxins, or abnormal proteins from the bloodstream. With increasing cases of autoimmune disorders like myasthenia gravis, Guillain-Barré syndrome, and multiple sclerosis, the demand for plasmapheresis has grown steadily.
Fact.MR's analysis estimates that the global plasmapheresis market is poised to experience healthy growth, driven by clinical efficacy, technological integration, and increasing investments in healthcare infrastructure. The market comprises two major types: automated plasmapheresis and manual plasmapheresis, with the former dominating due to precision and speed.
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Key Market Drivers
Rising Prevalence of Autoimmune and Chronic Diseases:The surge in autoimmune and chronic diseases globally is a primary growth driver. Diseases like systemic lupus erythematosus (SLE) and thrombotic thrombocytopenic purpura (TTP) are increasingly being treated with plasmapheresis, boosting its clinical demand.
Increased Demand for Plasma-Derived Medicinal Products (PDMPs)Plasma is rich in essential components such as immunoglobulins, clotting factors, and albumin. With growing demand for plasma-derived therapies, particularly for treating immune deficiencies and hemophilia, plasmapheresis plays a pivotal role in plasma collection, thus fostering market growth.
Technological Advancements in Apheresis Devices:The shift toward automation in apheresis systems has resulted in improved efficiency, lower turnaround times, and minimal manual intervention. Companies are investing heavily in R&D to design next-gen plasmapheresis machines with integrated data analytics, enhanced safety profiles, and portability.
Expansion of Blood Donation and Collection Centers:Increased government and non-profit initiatives for voluntary plasma donation programs, especially in countries like the U.S., Germany, and China, have expanded the scope of plasmapheresis procedures.
Market Challenges
While the market outlook is positive, there are several challenges that could restrain growth:
High cost of equipment and procedures can limit access in low- and middle-income regions.
Risk of adverse effects such as infections, hypotension, or allergic reactions can impact patient willingness.
Stringent regulatory requirements related to plasma collection, safety, and donor eligibility affect operational agility for healthcare providers.
Key Segments
By Product Type:
Devices
Disposables
Devices account for the largest market share due to recurring advancements and integration with hospital information systems. Disposables are essential for hygiene and patient safety, and their demand is steadily rising.
By Technology:
Centrifugal Plasmapheresis
Membrane Plasmapheresis
Centrifugal technology dominates due to its speed, minimal invasiveness, and ability to process larger volumes of blood. Membrane-based methods are increasingly used in selective cases and are gaining attention due to their gentler processing capabilities.
By Application:
Neurological Disorders
Hematologic Disorders
Autoimmune Diseases
Others (e.g., metabolic disorders)
Neurological disorders lead in terms of application, with plasmapheresis being a frontline treatment in cases like acute inflammatory demyelinating polyneuropathy.
By End User:
Hospitals
Blood Donation Centers
Academic & Research Institutes
Hospitals remain the dominant end-user category, while blood donation centers are rapidly expanding due to the rise in plasma donation campaigns.
Regional Insights
North America:The U.S. is the largest market for plasmapheresis, bolstered by a robust healthcare system, high number of voluntary donors, and widespread use of apheresis technologies. The presence of major players like Haemonetics Corporation and Terumo BCT Inc. also supports market dominance.
Europe:Germany, France, and the UK lead the European market. Government-backed health programs and increasing demand for PDMPs are fostering market growth.
Asia-Pacific:This region is expected to witness the fastest growth due to rising healthcare awareness, government initiatives for infrastructure development, and an expanding patient base. Countries like India, China, and Japan are focal points for market expansion.
Latin America & MEA:Although in early stages, the market in these regions is gradually developing, supported by improvements in hospital systems and medical training.
Competitive Landscape
The plasmapheresis market is moderately consolidated, with a few key players accounting for significant shares. Some of the notable companies include:
Haemonetics Corporation
Terumo BCT Inc.
Fresenius Kabi
Baxter International Inc.
Asahi Kasei Medical Co., Ltd.
Braun Melsungen AG
These companies are focusing on strategic collaborations, product launches, and expansion into emerging markets to gain competitive advantages.
Recent Developments:
Haemonetics launched next-gen NexSys PCS®, an advanced plasma collection system designed to increase yield and safety.
Baxter introduced new apheresis disposables compatible with multiple systems to enhance operational flexibility.
Asahi Kasei is actively working on membrane-based plasmapheresis innovations, targeting low-resource settings.
Future Opportunities
The plasmapheresis market presents numerous opportunities for future growth:
Portable plasmapheresis devices for home-based care settings.
Artificial intelligence and machine learning integration for personalized treatment protocols.
Telemedicine-supported apheresis therapy, especially in remote areas.
Strategic partnerships between biotech firms and healthcare facilities to streamline supply chains and increase access.
Moreover, public-private partnerships to promote blood donation and expand plasma centers in underdeveloped regions are expected to unlock untapped potential.
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Conclusion
Plasmapheresis is a critical medical procedure at the intersection of therapeutic innovation and compassionate care. As the burden of chronic and autoimmune diseases rises globally, this technology offers a scalable and effective treatment pathway. The Fact.MR report underlines that with continued technological development, growing awareness, and strategic investments, the plasmapheresis market is set for robust growth in the years ahead.
Healthcare providers, manufacturers, and policymakers must work collaboratively to ensure that these life-saving therapies are accessible, affordable, and safe for all who need them.
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