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RAS-acting Agents Market Size Will Expected to Surpass US$ 13.4 Billion [by 2031], Growing at 4.2% CAGR - Transparency Market Research Inc.

03-25-2025 09:30 AM CET | Health & Medicine

Press release from: Transparency Market Research

RAS-acting Agents

RAS-acting Agents

RAS-acting agents play a crucial role in managing hypertension and cardiovascular diseases by targeting the renin-angiotensin system. These agents, including ACE inhibitors, angiotensin receptor blockers (ARBs), and direct renin inhibitors, are widely prescribed due to their proven efficacy and safety. The increasing prevalence of cardiovascular disorders, rising geriatric population, and growing awareness about hypertension management are key factors driving the expansion of the global RAS-acting agents market.

The global RAS-acting agents market was valued at US$ 9.7 billion in 2022 and is projected to grow at a CAGR of 4.2% from 2023 to 2031. By the end of 2031, the market is expected to surpass US$ 13.4 billion. The increasing burden of hypertension, growing demand for combination therapies, and advancements in drug formulations are fueling market growth.

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Analyst Viewpoint

Industry experts anticipate steady growth in the RAS-acting agents market, driven by increasing healthcare expenditure, expanding generic drug production, and the rising adoption of combination therapies. However, patent expirations of key drugs, regulatory hurdles, and potential side effects associated with RAS inhibitors may present challenges to market expansion.

Market Demand and Key Drivers

Rising Prevalence of Hypertension and Cardiovascular Diseases: The growing number of patients with high blood pressure and cardiovascular conditions is driving demand for RAS inhibitors.

Increasing Geriatric Population: Elderly individuals are more susceptible to hypertension, fueling market demand.

Growing Adoption of Combination Therapies: The preference for fixed-dose combinations of RAS inhibitors with other antihypertensive agents is increasing.

Expanding Generic Drug Market: The expiration of patents for blockbuster RAS inhibitors is leading to the entry of cost-effective generic alternatives.

Advancements in Drug Formulations: Innovations in extended-release and combination formulations are enhancing patient compliance and treatment outcomes.

Government Initiatives for Hypertension Management: Public health campaigns and awareness programs are promoting early diagnosis and treatment adherence.

Recent Developments

2023, Novartis: Launched a new combination therapy incorporating RAS inhibitors for hypertension management.

2023, Pfizer: Expanded its cardiovascular drug portfolio with the acquisition of a leading hypertension drug manufacturer.

2024, Merck & Co.: Received regulatory approval for a novel RAS-acting agent with improved safety profile.

2024, AstraZeneca: Partnered with healthcare organizations to improve access to antihypertensive therapies in emerging markets.

2024, Sanofi: Introduced a biosimilar version of a widely used angiotensin receptor blocker.

Key Market Players

Novartis AG
Pfizer, Inc.
AstraZeneca plc
Merck & Co., Inc.
Sanofi S.A.
Bristol-Myers Squibb Company
Daiichi Sankyo Company, Limited
Takeda Pharmaceutical Company Limited
Boehringer Ingelheim GmbH
Johnson & Johnson
Other Prominent Players

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Future Market Analysis

The RAS-acting agents market is expected to maintain a steady growth trajectory, driven by rising awareness of hypertension management, continuous innovation in drug formulations, and expanding access to affordable treatments. The development of next-generation RAS inhibitors and biosimilars will further enhance market opportunities, while strategic collaborations among pharmaceutical companies will accelerate drug discovery and commercialization efforts.

Market Trends and Opportunities

Shift Towards Personalized Medicine: Tailored treatment approaches based on genetic and phenotypic profiling are improving patient outcomes.

Growth in Fixed-Dose Combination Therapies: The increasing preference for single-pill combinations is enhancing treatment adherence.

Expansion in Emerging Markets: Developing regions are witnessing rising demand for affordable antihypertensive medications.

Development of Novel RAS-acting Agents: Research on next-generation inhibitors with enhanced efficacy and reduced side effects is ongoing.

Increasing Healthcare Investments: Government and private sector funding in cardiovascular healthcare is supporting market growth.

Market Segmentation

By Drug Class:

ACE Inhibitors
Angiotensin Receptor Blockers (ARBs)
Direct Renin Inhibitors
Others

By Distribution Channel:

Hospital Pharmacies
Retail Pharmacies
Online Pharmacies

By Application:

Hypertension
Heart Failure
Chronic Kidney Disease
Others

Regional Analysis

North America: The largest market due to high disease prevalence, advanced healthcare infrastructure, and strong regulatory support.

Europe: Significant growth driven by increasing adoption of generic drugs and combination therapies.

Asia-Pacific: The fastest-growing region due to rising cardiovascular disease burden and improving healthcare accessibility.

Latin America & Middle East/Africa: Emerging markets with increasing healthcare spending and demand for affordable RAS-acting agents.

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Transparency Market Research Inc.
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Suite 1200, Wilmington, Delaware 19801 USA
Phone: +1-518-618-1030
US - Canada Toll Free: 866-552-3453
Website: https://www.transparencymarketresearch.com

About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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