Glioblastoma Multiforme Market Growth to Accelerate in Forecast Period (2024-2034), DelveInsight Analyzes | AstraZeneca, DNAtrix, Chimerix, Northwest Therapeutics, Bayer, Kazia Therapeutics, Aivita Biomedical

DelveInsight's "Glioblastoma Multiforme Market Insights, Epidemiology, and Market Forecast-2034′′ report offers an in-depth understanding of the Glioblastoma Multiforme, historical and forecasted epidemiology as well as the Glioblastoma Multiforme market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

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Some of the key facts of the Glioblastoma Multiforme Market Report:
• The Glioblastoma Multiforme market size was valued approximately USD 835 million in 2023 and is anticipated to grow with a significant CAGR during the study period (2020-2034)
• In January 2025, The Ivy Brain Tumor Center at Barrow Neurological Institute announced the expansion of the Gliofocus Study by adding two new sites in Europe and two more in the United States. The newly activated locations include Groupe Hospitalier Pitié-Salpêtrière in Paris, France; Hospital Universitario 12 de Octubre in Madrid, Spain; The NeuroMedical Center Clinic in Baton Rouge, Louisiana; and UC San Diego Moores Cancer Center in La Jolla, California. The Gliofocus Study is an open-label, randomized Phase 3 trial (NCT06388733) evaluating the efficacy of niraparib, a PARP1/2 selective inhibitor, compared to temozolomide in adult patients with newly diagnosed MGMT-unmethylated glioblastoma.
• In January 2025, Imvax secured $29 million in funding from existing investors to support the Phase IIb trial of IGV-001, its autologous biologic-device combination therapy for newly diagnosed glioblastoma (ndGBM). With this latest investment, the company's total fundraising over the past 21 months has reached $86 million. The randomized, multi-center, placebo-controlled, double-blind trial aims to assess the efficacy and safety of the treatment.
• In November 2024, Kazia Therapeutics revealed that the FDA has scheduled a Type C meeting for December 2024 to explore possible registration pathways for paxalisib, the company's blood-brain barrier-penetrant PI3K/mTOR inhibitor, aimed at treating newly diagnosed Glioblastoma Multiforme.
• In November 2024, Novocure announced that the US FDA has approved its new HFE transducer arrays for use with OPTUNE GIO in the treatment of adult patients with Glioblastoma Multiforme
• In April 2024, Enterome reported the successful completion of the Phase II ROSALIE trial evaluating EO2401 for recurrent glioblastoma.
• In March 2024, the US FDA cleared TME Pharma's IND application for NOX-A12 based on the protocol for its upcoming randomized Phase II trial in Glioblastoma Multiforme.
• CNS Pharmaceuticals announced that the enrollment of the Phase II trial of berubicin was completed in a potentially pivotal Glioblastoma Multiforme study evaluating berubicin, and the topline data is expected in the first half of 2025.
• Among the 7MM, the United States held the highest market share for Glioblastoma Multiforme treatment, amounting to approximately USD 70 million in 2023.
• In 2023, the distribution of incident cases of Glioblastoma Multiforme across the 7MM showed that the US contributed around 41%, while EU4 and the UK collectively accounted for 51%, and Japan represented 8% of the total cases.
• In 2023, within the EU4 and the UK, glioblastoma had the highest number of incident cases based on histological classification, totaling around 17,550 cases. In contrast, giant cell glioblastoma had the fewest cases, approximately 150, with numbers projected to rise by 2034.
• In Japan, during 2023, the largest share of cases in the targeted therapy pool was attributed to first-line treatments, totaling 2,690 cases, followed by second-line and subsequent treatments, which accounted for 1,365 cases.
• Key Glioblastoma Multiforme Companies: Bayer, VBL Therapeutics, AstraZeneca, DNAtrix,Kintara Pharmaceuticals, Chimerix, KaryoPharma, VBI Vaccines, Kazia Therapeutics, AivitaBiomedical, Medicenna Therapeutics, Immunomic Therapeutics, Treovir, Istari Oncology,Inovio Pharmaceuticals, Northwest Biotherapeutics and others
• Key Glioblastoma Multiforme Therapies: Durvalumab, DNX-2401, ONC201, DCVax-L, Regorafenib, Paxalisib(GDC-0084), AV-GBM-1, MDNA55, VAL-083, and others
• The Glioblastoma Multiforme epidemiology based on gender analyzed that Glioblastoma Multiforme is more prevalent among males than females
• The Glioblastoma Multiforme market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Glioblastoma Multiforme pipeline products will significantly revolutionize the Glioblastoma Multiforme market dynamics.

Glioblastoma Multiforme Overview
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant brain tumor, classified as a grade IV astrocytoma. It originates from the supportive tissue of the brain called glial cells, specifically astrocytes. GBM is highly invasive, infiltrating nearby brain tissue, and rapidly growing, often leading to significant neurological symptoms and poor prognosis.

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Glioblastoma Multiforme Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Glioblastoma Multiforme Epidemiology Segmentation:
The Glioblastoma Multiforme market report proffers epidemiological analysis for the study period 2020-2034 in the 7MM segmented into:
• Total Prevalence of Glioblastoma Multiforme
• Prevalent Cases of Glioblastoma Multiforme by severity
• Gender-specific Prevalence of Glioblastoma Multiforme
• Diagnosed Cases of Episodic and Chronic Glioblastoma Multiforme

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Glioblastoma Multiforme Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Glioblastoma Multiforme market or expected to get launched during the study period. The analysis covers Glioblastoma Multiforme market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Glioblastoma Multiforme Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Glioblastoma Multiforme Therapies and Key Companies
• Durvalumab: AstraZeneca
• DNX-2401: DNAtrix
• ONC201: Chimerix
• DCVax-L: Northwest Therapeutics
• Regorafenib: Bayer
• Paxalisib(GDC-0084): Kazia Therapeutics
• AV-GBM-1: Aivita Biomedical
• MDNA55: Medicenna Therapeutics
• VAL-083: Kintara Therapeutics

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Glioblastoma Multiforme Market Strengths
• Vaccine approaches are an attractive adjuvant therapy for solid tumors because they can generate long-term immune surveillance against cancer cells. MimiVax (SurVaxM), Immunomic Therapeutics (ITI-1000), and IMVAX (IGV-001) are some of the key players developing therapeutic vaccines for GBM
• Owing to the launch of bevacizumab biosimilars, a reduction in cost burden can be witnessed

Glioblastoma Multiforme Market Opportunities
• Numerous failed clinical trials suggest combination therapies willikely be the most promising method of GBM treatment, and emphasis should be applied to drug design and pharmacokinetic properties
• Better prognostic markers would allow physicians to diagnose and begin treatment of GBM at early onset, possibly preventing disease progression

Scope of the Glioblastoma Multiforme Market Report
• Study Period: 2020-2034
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Glioblastoma Multiforme Companies: Bayer, VBL Therapeutics, AstraZeneca, DNAtrix,Kintara Pharmaceuticals, Chimerix, KaryoPharma, VBI Vaccines, Kazia Therapeutics, AivitaBiomedical, Medicenna Therapeutics, Immunomic Therapeutics, Treovir, Istari Oncology,Inovio Pharmaceuticals, Northwest Biotherapeutics, and others
• Key Glioblastoma Multiforme Therapies: Durvalumab, DNX-2401, ONC201, DCVax-L, Regorafenib, Paxalisib(GDC-0084), AV-GBM-1, MDNA55, VAL-083, and others
• Glioblastoma Multiforme Therapeutic Assessment: Glioblastoma Multiforme current marketed and Glioblastoma Multiforme emerging therapies
• Glioblastoma Multiforme Market Dynamics: Glioblastoma Multiforme market drivers and Glioblastoma Multiforme market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Glioblastoma Multiforme Unmet Needs, KOL's views, Analyst's views, Glioblastoma Multiforme Market Access and Reimbursement

To know more about Glioblastoma Multiforme companies working in the treatment market, visit @ Glioblastoma Multiforme Clinical Trials and Therapeutic Assessment
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Table of Contents
1. Glioblastoma Multiforme Market Report Introduction
2. Executive Summary for Glioblastoma Multiforme
3. SWOT analysis of Glioblastoma Multiforme
4. Glioblastoma Multiforme Patient Share (%) Overview at a Glance
5. Glioblastoma Multiforme Market Overview at a Glance
6. Glioblastoma Multiforme Disease Background and Overview
7. Glioblastoma Multiforme Epidemiology and Patient Population
8. Country-Specific Patient Population of Glioblastoma Multiforme
9. Glioblastoma Multiforme Current Treatment and Medical Practices
10. Glioblastoma Multiforme Unmet Needs
11. Glioblastoma Multiforme Emerging Therapies
12. Glioblastoma Multiforme Market Outlook
13. Country-Wise Glioblastoma Multiforme Market Analysis (2020-2034)
14. Glioblastoma Multiforme Market Access and Reimbursement of Therapies
15. Glioblastoma Multiforme Market Drivers
16. Glioblastoma Multiforme Market Barriers
17. Glioblastoma Multiforme Appendix
18. Glioblastoma Multiforme Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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