Press release
Myelofibrosis Market is Expected to Flourish in 7MM, Expanding from USD 1.7 Billion in 2024 | DelveInsight
The myelofibrosis treatment market is going to witness robust growth owing to the launch of emerging therapies by key players such as Abbvie, Morphosys, Geron, Bristol Myers Squibb, Kartos Therapeutics, Karyopharm Therapeutics, Ns Pharma, Galecto Biotech, Actuate Therapeutics, Merck, Menarini Group, Telios Pharma, Disc Medicine, Syntara, Sumitomo Pharma, and Incyte, among others, which are advancing myelofibrosis research to address unmet needs.
DelveInsight's "Myelofibrosis Market Insight, Epidemiology And Market Forecast - 2034 [https://www.delveinsight.com/report-store/myelofibrosis-mf-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr]" report provides an in-depth understanding of Myelofibrosis, historical and forecasted epidemiology, as well as the Myelofibrosis market trends in the 7MM which include the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
The myelofibrosis market size, valued at ~USD 1.7 billion in 2024, is projected to expand at a rapid CAGR over the forecasted period (2025-2034). This growth is fueled by rising disease prevalence, improved diagnostic capabilities, and the launch of novel therapies targeting diverse patient subgroups. Among all the therapies, JAKAFI/JAKAVI (ruxolitinib) accounted for the largest myelofibrosis market size in 2024, with USD 1.5 Billion.
Download the myelofibrosis market report to understand which factors are driving the myelofibrosis market @ myelofibrosis Market Trends [https://www.delveinsight.com/sample-request/myelofibrosis-mf-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr]
The report provides a comprehensive epidemiological analysis and forecasts extending to 2034. This analysis is segmented by total myelofibrosis prevalent cases, type-specific cases, myelofibrosis cases based on risk stratification, age-specific myelofibrosis cases, and myelofibrosis cases based on molecular alterations in the 7MM.
According to DelveInsight's analysis, the total myelofibrosis prevalence in the 7MM was nearly 56K in 2024. High-risk myelofibrosis accounted for the largest patient population in the US, with primary myelofibrosis making up approximately 75% of all cases. This trend is expected to continue in the forecasted period (2025-2034).
For most people with myelofibrosis, treatment remains aimed at controlling disease symptoms and complications, enhancing the quality of life, and extending survival. Key marketed therapies include JAKAFI (ruxolitinib) and INREBIC (fedratinib), which have dominated the landscape as JAK inhibitors provide unprecedented benefits to myelofibrosis patients in terms of spleen shrinkage and symptom improvement. However, the patent for JAKAFI is expected to go off in 2027 for Novartis and in 2028 for Incyte, opening up opportunities for emerging therapies.
As JAK inhibitor therapy is linked with certain complications, new treatments for myelofibrosis are focusing on mechanisms other than JAK inhibitors. These include imetelstat (telomerase inhibitor), navtemadlin (MDM2 protein inhibitor), pelabresib (BET inhibitor), and others that may meet the patient's needs and provide an alternative myelofibrosis treatment.
According to DelveInsight's analysis, the myelofibrosis competitive landscape is further enriched by several companies initiating clinical trials for new options. The pipeline includes drugs such as BESREMi (PharmaEssentia and AOP Orphan Pharmaceuticals), INCB057643 (Incyte), XPOVIO (Karyopharm Therapeutics), RYTELO (Geron), REBLOZYL (Bristol Myers Squibb and Merck), Navtemadlin (Kartos Therapeutics), Pelabresib (Novartis), Bomedemstat (Merck), TL-895 (Telios Pharma), RVU120 (Ryvu Therapeutics), TP-3654 (Sumitomo Pharma), SNT-5505 (Syntara), DISC-0974 (Disc Medicine), and ELZONRIS (Menarini Group), among others.
Discover evolving trends in myelofibrosis treatment landscape @ myelofibrosis therapies [https://www.delveinsight.com/sample-request/myelofibrosis-mf-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr]
Other than JAKAFI and INREBIC, the current myelofibrosis treatment landscape also includes approved drugs like VONJO (CTI BioPharma), a JAK2/IRAK1 inhibitor, approved back in 2022 for the treatment of adults with the intermediate or high-risk primary or secondary myelofibrosis. OJJAARA (GSK), a JAK1/2 and ACVR1 inhibitor targeting anemia, which is the only approved agent for both newly diagnosed and previously treated patients with myelofibrosis and anemia, was approved in 2023. Omjjara's unique mechanism addressing hepcidin dysregulation positions it to reshape the secondary myelofibrosis treatment market, particularly for anemic patients who face limited options.
According to DelveInsight's analysis, the myelofibrosis competitive landscape is further enriched by several companies initiating clinical trials for new options. The pipeline includes drugs such as BESREMi (PharmaEssentia and AOP Orphan Pharmaceuticals), INCB057643 (Incyte), XPOVIO (Karyopharm Therapeutics), RYTELO (Geron), REBLOZYL (Bristol Myers Squibb and Merck), Navtemadlin (Kartos Therapeutics), Pelabresib (Novartis), Bomedemstat (Merck), TL-895 (Telios Pharma), RVU120 (Ryvu Therapeutics), TP-3654 (Sumitomo Pharma), SNT-5505 (Syntara), DISC-0974 (Disc Medicine), and ELZONRIS (Menarini Group), among others.
Unlock which myelofibrosis emerging drug is expected to capture the largest market share in 7MM by 2034. Visit the Myelofibrosis Market Insights [https://www.delveinsight.com/sample-request/myelofibrosis-mf-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr]
The myelofibrosis treatment clinical trial pipeline is currently active, with notable recent breakthroughs. In January 2025, the BOREAS phase 3 trial demonstrated that navtemadlin, an MDM2 inhibitor, offers clinical benefits as a single agent in JAK inhibitor-refractory myelofibrosis, showing durable spleen volume reductions and symptom improvements. In March 2025, a Phase 3 trial showed that adding pelebresib to ruxolitinib was more effective than ruxolitinib alone in treating myelofibrosis, with significant spleen shrinkage and no substantial increase in side effects. These recent findings indicate a strong upward trend in the myelofibrosis treatment market.
Despite these advancements, challenges persist. Long-term JAK inhibitor use is linked to cytopenias and infections, while high treatment costs and accessibility barriers limit global reach. DelveInsight's analysis emphasizes the need for cost-effective therapies and personalized approaches leveraging genetic profiling.
Looking ahead, the myelofibrosis treatment market is poised for diversification with a robust developmental pipeline, including BET inhibitors, PI3K inhibitors, and immunomodulators. The integration of biomarkers and combination regimens is expected to enhance response durability and address resistance.
Table of Contents
1.
KEY INSIGHTS
2.
REPORT INTRODUCTION
3.
EXECUTIVE SUMMARY OF MYELOFIBROSIS
4.
EPIDEMIOLOGY AND MARKET METHODOLOGY
5.
KEY EVENTS
6.
MYELOFIBROSIS MARKET OVERVIEW AT A GLANCE
7.
DISEASE BACKGROUND AND OVERVIEW
8.
TREATMENT AND MANAGEMENT
9.
GUIDELINES
10.
EPIDEMIOLOGY AND PATIENT POPULATION
11.
PATIENT JOURNEY
12.
KEY ENDPOINTS IN MYELOFIBROSIS CLINICAL TRIALS
13.
MARKETED DRUGS
14.
EMERGING THERAPIES
15.
MYELOFIBROSIS: 7 MAJOR MARKET ANALYSIS
16.
MARKET ACCESS AND REIMBURSEMENT
17.
SWOT ANALYSIS
18.
UNMET NEEDS
19.
KOL VIEWS
20.
APPENDIX
21.
DELVEINSIGHT CAPABILITIES
22.
DISCLAIMER
23.
ABOUT DELVEINSIGHT
Related Report
Myelofibrosis Pipeline Insight [https://www.delveinsight.com/report-store/myelofibrosis-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=xpr]
Myelofibrosis Pipeline Insight provides comprehensive insights about the Myelofibrosis pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the Myelofibrosis companies, including Geron Corporation, Merck, Telios Pharma, Inc., Ryvu Therapeutics SA, Taiga Biotechnologies, Inc., Morphic Therapeutic, iOnctura, Pharmaxis, Nippon Shinyaku, Active Biotech, Incyte Corporation, and Sumitomo Pharma America, Inc. among others.
About DelveInsight
DelveInsight is a leading market research and consulting firm specializing in disease-specific insights and therapeutic market analysis. Their reports integrate real-world data, clinical trial findings, and expert interviews to deliver comprehensive industry intelligence.
Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Arpit Anand
Email:Send Email [https://www.abnewswire.com/email_contact_us.php?pr=myelofibrosis-market-is-expected-to-flourish-in-7mm-expanding-from-usd-17-billion-in-2024-delveinsight]
Phone: +14699457679
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: Nevada
Country: United States
Website: https://www.delveinsight.com/consulting/due-diligence-services
Legal Disclaimer: Information contained on this page is provided by an independent third-party content provider. ABNewswire makes no warranties or responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you are affiliated with this article or have any complaints or copyright issues related to this article and would like it to be removed, please contact retract@swscontact.com
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Myelofibrosis Market is Expected to Flourish in 7MM, Expanding from USD 1.7 Billion in 2024 | DelveInsight here
News-ID: 3924802 • Views: …
More Releases from ABNewswire
Improving Social Skills and Communication: Flywheel Centers Details the Benefits …
Flywheel Centers explains how ABA therapy improves social skills and communication in children with autism in Charlotte, NC, offering personalized support for growth.
Charlotte, NC - Autism Spectrum Disorder (ASD) is a developmental condition that affects how individuals communicate, interact, and process information. For families in Charlotte, NC, seeking effective therapies to support their loved ones with autism, Applied Behavior Analysis (ABA) therapy has proven to be a valuable tool. ABA…
Stellar Scientific Explains Why Gravity Convection Ovens Are Perfect for Delicat …
Stellar Scientific explains how gravity convection ovens ensure consistent and delicate heating, making them perfect for precision cooking in various industries.
In laboratory and industrial environments, precision and consistency are crucial when it comes to heating applications. Whether it's for drying, sterilizing, or sample preparation, a stable and uniform heat distribution ensures accurate results. Gravity convection ovens, known for their reliability and delicate temperature control, are an ideal solution for such…
Unlocking Potential with ABA Therapy: How A Gem of Joy ABA Helps Children with A …
A Gem of Joy ABA in Baltimore, MD, uses ABA therapy to unlock potential in children with autism, helping them develop key skills for a brighter future.
Baltimore, MD - Autism Spectrum Disorder (ASD) affects millions of children worldwide, presenting unique challenges in communication, behavior, and social interaction. For families in Baltimore, MD, finding effective therapies is essential in helping children with autism reach their full potential. A Gem of Joy…
The Healing Power of Art: How Creative Therapy Zone in Thornhill, ON, Uses Art T …
Creative Therapy Zone in Thornhill, ON, harnesses the healing power of art therapy, helping individuals improve mental wellness through creative expression and support.
Thornhill, ON - Mental wellness is an essential aspect of overall health, and individuals facing mental health challenges often seek therapeutic approaches that go beyond traditional talk therapy. Art therapy has emerged as a powerful tool for individuals looking to express themselves, process emotions, and heal through creativity.…
More Releases for Pharma
Miglitol Market Size, Share and Forecast By Key Players-Weiao Pharma, Zhejiang M …
𝐔𝐒𝐀, 𝐍𝐞𝐰 𝐉𝐞𝐫𝐬𝐞𝐲- According to the MRI Team's Market Research Intellect, the global Miglitol market is anticipated to grow at a compound annual growth rate (CAGR) of 11.49% between 2024 and 2031. The market is expected to grow to USD 22.32 Billion by 2024. The valuation is expected to reach USD 47.79 Billion by 2031.
The Miglitol market is experiencing significant growth due to the rising prevalence of diabetes and the increasing awareness of the…
Dacarbazine Market Size, Share and Forecast By Key Players-Lingnan Pharma, Ruiyi …
𝐔𝐒𝐀, 𝐍𝐞𝐰 𝐉𝐞𝐫𝐬𝐞𝐲- According to the MRI Team's Market Research Intellect, the global Dacarbazine market is anticipated to grow at a compound annual growth rate (CAGR) of 14.63% between 2024 and 2031. The market is expected to grow to USD 25.32 Billion by 2024. The valuation is expected to reach USD 65.84 Billion by 2031.
The Dacarbazine market is projected to witness significant growth in the coming years, driven by increasing…
Dacarbazine Market Size, Share and Forecast By Key Players-Lingnan Pharma, Ruiyi …
𝐔𝐒𝐀, 𝐍𝐞𝐰 𝐉𝐞𝐫𝐬𝐞𝐲- According to the MRI Team's Market Research Intellect, the global Dacarbazine market is anticipated to grow at a compound annual growth rate (CAGR) of 14.63% between 2024 and 2031. The market is expected to grow to USD 25.32 Billion by 2024. The valuation is expected to reach USD 65.84 Billion by 2031.
The dacarbazine market is experiencing steady growth, driven by the rising incidence of cancer globally. As…
Epilepsy Pipeline Assessment 2024: Therapies, Clinical Trials, and Market Insigh …
(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Epilepsy pipeline constitutes 75+ key companies continuously working towards developing 90+ Epilepsy treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.
The Epilepsy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the…
Global Indomethacin Market Seeking Excellent Growth by 2028 | Ratiopharm, Merck, …
"IBI has published a report entitled Global Indomethacin Market Research Report which provides comprehensive data on emerging trends, market drivers, growth opportunities, and barriers that could change the dynamics of the industry market. It provides an in-depth analysis of market segments which includes the product, application, and competitor analysis.
Click Here To Order A Sample Copy Of Indomethacin Global Market Report : https://www.infinitybusinessinsights.com/request_sample.php?id=380382
The Indomethacin Global Market Research Report provides close monitoring…
Roxatidine Market 2020: Top Companies Analysis To Grow Healthcare Business by 20 …
Business Industry Reports Research has recently announced a report on Global Roxatidine Market based on the Category Industry. The Roxatidine Market report emphasizes various key aspects, which include growth drivers, restraints, opportunities and recent market trends for the forecast period 2020-2024.
Global Roxatidine Market overview:
Business Industry Reports Analyst covers the Major Players data, including: shipment, revenue, gross profit, interview record, business distribution etc., these data help the consumer know about the…
