Actinium-225 Market to Reach $1.8 Million by 2031, Driven by 15.2% CAGR Growth | ORNL, Tri-Lab, SSC RF-IPPE, JRC Karlsruhe

LOS ANGELES, United States: The global Actinium-225 (Ac-225) market is on a remarkable growth trajectory, driven by its potential in targeted alpha therapy (TAT) for cancer treatment and its significance in scientific research. According to QYResearch, the market was valued at $700 thousand in 2024 and is projected to reach $1.8 million by 2031, expanding at a CAGR of 15.2%.

Global key players of Actinium-225 include ORNL, Tri-Lab, SSC RF-IPPE, etc. The top three players hold a share about 72%. North America is the largest market, and has a share about 67%. In terms of product type, Thorium-229 Decay is the largest segment, accounting for a share of 71%. In terms of application, Scientific Research is the largest field with a share about 65 percent.

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Market Overview & Key Segments

Actinium-225 is a synthetic isotope primarily produced through Thorium-229 decay or particle accelerator methods. It is a powerful tool in the medical field, particularly in radiopharmaceuticals used for cancer therapy, yet its limited availability poses a challenge.

Leading Production Methods:

Thorium-229 Decay: The dominant production method, accounting for 61.5% market share.

Accelerator-Based Production: A growing segment as demand for Actinium-225 increases.

Top Applications:

Scientific Research: The largest segment, holding 68.4% of the market share.

Cancer Therapy: A rapidly expanding field with increasing clinical trials in nuclear medicine.

Market Drivers & Growth Factors

🚀 Rising Demand for Cancer Therapy

Actinium-225 is a key isotope in targeted alpha therapy (TAT), an advanced cancer treatment method that minimizes damage to healthy tissues while effectively destroying cancer cells.

Ongoing clinical trials are exploring its potential in treating leukemia, prostate cancer, and neuroendocrine tumors.

🔬 Scientific Research Expansion

The isotope is also widely used in research fields, particularly in nuclear medicine and radiochemistry.

Government and private sector investments are driving research into improved production and application techniques.

🌍 Technological Advancements in Production

Limited supply has been a major constraint, but innovations in cyclotron and accelerator-based production are helping scale up output and meet growing global demand.

Challenges & Market Constraints

⚠️ Limited Production Capabilities

Actinium-225 is not naturally abundant and is only synthesized in small quantities, making large-scale commercialization difficult.

💰 High Production Costs

The complex process of producing Ac-225 results in high costs, limiting accessibility for widespread clinical use.

🔍 Regulatory Challenges

Due to its use in nuclear medicine, strict government regulations impact production, distribution, and application in healthcare.

Competitive Landscape & Key Players

The top five manufacturers hold approximately 74% of the global market share. Key players include:

🏭 ORNL (Oak Ridge National Laboratory)
🏭 TerraPower
🏭 Tri-Lab
🏭 SSC RF-IPPE
🏭 Eckert & Ziegler

Future Outlook

With technological advancements, increasing clinical trials, and rising government investments, the Actinium-225 market is set for significant expansion. The growing demand for targeted cancer therapies and the expansion of nuclear medicine research will further drive this market, making it a key focus area in the healthcare and scientific industries.

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Table of Contents

1 Actinium-225 Market Overview
1.1 Product Definition
1.2 Actinium-225 by Type
1.2.1 Global Actinium-225 Market Value Growth Rate Analysis by Type: 2024 VS 2031
1.2.2 Accelerator
1.2.3 Thorium-229 Decay
1.3 Actinium-225 by Application
1.3.1 Global Actinium-225 Market Value Growth Rate Analysis by Application: 2024 VS 2031
1.3.2 Scientific Research
1.3.3 Cancer Therapy
1.4 Global Market Growth Prospects
1.4.1 Global Actinium-225 Production Value Estimates and Forecasts (2020-2031)
1.4.2 Global Actinium-225 Production Capacity Estimates and Forecasts (2020-2031)
1.4.3 Global Actinium-225 Production Estimates and Forecasts (2020-2031)
1.4.4 Global Actinium-225 Market Average Price Estimates and Forecasts (2020-2031)
1.5 Assumptions and Limitations

2 Market Competition by Manufacturers
2.1 Global Actinium-225 Production Market Share by Manufacturers (2020-2025)
2.2 Global Actinium-225 Production Value Market Share by Manufacturers (2020-2025)
2.3 Global Key Players of Actinium-225, Industry Ranking, 2023 VS 2024
2.4 Global Actinium-225 Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
2.5 Global Actinium-225 Average Price by Manufacturers (2020-2025)
2.6 Global Key Manufacturers of Actinium-225, Manufacturing Base Distribution and Headquarters
2.7 Global Key Manufacturers of Actinium-225, Product Offered and Application
2.8 Global Key Manufacturers of Actinium-225, Date of Enter into This Industry
2.9 Actinium-225 Market Competitive Situation and Trends
2.9.1 Actinium-225 Market Concentration Rate
2.9.2 Global 5 and 10 Largest Actinium-225 Players Market Share by Revenue
2.10 Mergers & Acquisitions, Expansion

3 Actinium-225 Production by Region
3.1 Global Actinium-225 Production Value Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
3.2 Global Actinium-225 Production Value by Region (2020-2031)
3.2.1 Global Actinium-225 Production Value by Region (2020-2025)
3.2.2 Global Forecasted Production Value of Actinium-225 by Region (2026-2031)
3.3 Global Actinium-225 Production Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
3.4 Global Actinium-225 Production Volume by Region (2020-2031)
3.4.1 Global Actinium-225 Production by Region (2020-2025)
3.4.2 Global Forecasted Production of Actinium-225 by Region (2026-2031)
3.5 Global Actinium-225 Market Price Analysis by Region (2020-2025)
3.6 Global Actinium-225 Production and Value, Year-over-Year Growth
3.6.1 North America Actinium-225 Production Value Estimates and Forecasts (2020-2031)
3.6.2 Europe Actinium-225 Production Value Estimates and Forecasts (2020-2031)

4 Actinium-225 Consumption by Region
4.1 Global Actinium-225 Consumption Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
4.2 Global Actinium-225 Consumption by Region (2020-2031)
4.2.1 Global Actinium-225 Consumption by Region (2020-2025)
4.2.2 Global Actinium-225 Forecasted Consumption by Region (2026-2031)
4.3 North America
4.3.1 North America Actinium-225 Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.3.2 North America Actinium-225 Consumption by Country (2020-2031)
4.3.3 U.S.
4.3.4 Canada
4.4 Europe
4.4.1 Europe Actinium-225 Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.4.2 Europe Actinium-225 Consumption by Country (2020-2031)
4.4.3 Germany
4.4.4 France
4.4.5 U.K.
4.4.6 Italy
4.4.7 Russia
4.5 Asia Pacific
4.5.1 Asia Pacific Actinium-225 Consumption Growth Rate by Region: 2020 VS 2024 VS 2031
4.5.2 Asia Pacific Actinium-225 Consumption by Region (2020-2031)
4.5.3 China
4.5.4 Japan
4.5.5 South Korea
4.5.6 China Taiwan
4.5.7 Southeast Asia
4.5.8 India
4.6 Latin America, Middle East & Africa
4.6.1 Latin America, Middle East & Africa Actinium-225 Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.6.2 Latin America, Middle East & Africa Actinium-225 Consumption by Country (2020-2031)
4.6.3 Mexico
4.6.4 Brazil
4.6.5 Turkey
4.6.6 GCC Countries

5 Segment by Type
5.1 Global Actinium-225 Production by Type (2020-2031)
5.1.1 Global Actinium-225 Production by Type (2020-2025)
5.1.2 Global Actinium-225 Production by Type (2026-2031)
5.1.3 Global Actinium-225 Production Market Share by Type (2020-2031)
5.2 Global Actinium-225 Production Value by Type (2020-2031)
5.2.1 Global Actinium-225 Production Value by Type (2020-2025)
5.2.2 Global Actinium-225 Production Value by Type (2026-2031)
5.2.3 Global Actinium-225 Production Value Market Share by Type (2020-2031)
5.3 Global Actinium-225 Price by Type (2020-2031)

6 Segment by Application
6.1 Global Actinium-225 Production by Application (2020-2031)
6.1.1 Global Actinium-225 Production by Application (2020-2025)
6.1.2 Global Actinium-225 Production by Application (2026-2031)
6.1.3 Global Actinium-225 Production Market Share by Application (2020-2031)
6.2 Global Actinium-225 Production Value by Application (2020-2031)
6.2.1 Global Actinium-225 Production Value by Application (2020-2025)
6.2.2 Global Actinium-225 Production Value by Application (2026-2031)
6.2.3 Global Actinium-225 Production Value Market Share by Application (2020-2031)
6.3 Global Actinium-225 Price by Application (2020-2031)

7 Key Companies Profiled
7.1 ORNL
7.1.1 ORNL Actinium-225 Company Information
7.1.2 ORNL Actinium-225 Product Portfolio
7.1.3 ORNL Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.1.4 ORNL Main Business and Markets Served
7.1.5 ORNL Recent Developments/Updates
7.2 Tri-Lab
7.2.1 Tri-Lab Actinium-225 Company Information
7.2.2 Tri-Lab Actinium-225 Product Portfolio
7.2.3 Tri-Lab Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.2.4 Tri-Lab Main Business and Markets Served
7.2.5 Tri-Lab Recent Developments/Updates
7.3 SSC RF-IPPE
7.3.1 SSC RF-IPPE Actinium-225 Company Information
7.3.2 SSC RF-IPPE Actinium-225 Product Portfolio
7.3.3 SSC RF-IPPE Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.3.4 SSC RF-IPPE Main Business and Markets Served
7.3.5 SSC RF-IPPE Recent Developments/Updates
7.4 JRC Karlsruhe
7.4.1 JRC Karlsruhe Actinium-225 Company Information
7.4.2 JRC Karlsruhe Actinium-225 Product Portfolio
7.4.3 JRC Karlsruhe Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.4.4 JRC Karlsruhe Main Business and Markets Served
7.4.5 JRC Karlsruhe Recent Developments/Updates
7.5 TerraPower
7.5.1 TerraPower Actinium-225 Company Information
7.5.2 TerraPower Actinium-225 Product Portfolio
7.5.3 TerraPower Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.5.4 TerraPower Main Business and Markets Served
7.5.5 TerraPower Recent Developments/Updates
7.6 TRIUMF
7.6.1 TRIUMF Actinium-225 Company Information
7.6.2 TRIUMF Actinium-225 Product Portfolio
7.6.3 TRIUMF Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.6.4 TRIUMF Main Business and Markets Served
7.6.5 TRIUMF Recent Developments/Updates
7.7 Eckert&Ziegler
7.7.1 Eckert&Ziegler Actinium-225 Company Information
7.7.2 Eckert&Ziegler Actinium-225 Product Portfolio
7.7.3 Eckert&Ziegler Actinium-225 Production, Value, Price and Gross Margin (2020-2025)
7.7.4 Eckert&Ziegler Main Business and Markets Served
7.7.5 Eckert&Ziegler Recent Developments/Updates

8 Industry Chain and Sales Channels Analysis
8.1 Actinium-225 Industry Chain Analysis
8.2 Actinium-225 Raw Material Supply Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.3 Actinium-225 Production Mode & Process Analysis
8.4 Actinium-225 Sales and Marketing
8.4.1 Actinium-225 Sales Channels
8.4.2 Actinium-225 Distributors
8.5 Actinium-225 Customer Analysis

9 Actinium-225 Market Dynamics
9.1 Actinium-225 Industry Trends
9.2 Actinium-225 Market Drivers
9.3 Actinium-225 Market Challenges
9.4 Actinium-225 Market Restraints

10 Research Findings and Conclusion

11 Methodology and Data Source
11.1 Methodology/Research Approach
11.1.1 Research Programs/Design
11.1.2 Market Size Estimation
11.1.3 Market Breakdown and Data Triangulation
11.2 Data Source
11.2.1 Secondary Sources
11.2.2 Primary Sources
11.3 Author List
11.4 Disclaimer

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