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Oligonucleotide Synthesis Market Set to Reach $22.29 Billion by 2029 with 17% Yearly Growth

03-05-2025 12:29 PM CET | Health & Medicine

Press release from: The Business Research Company

Oligonucleotide Synthesis Market Size

Oligonucleotide Synthesis Market Size

How Are the key drivers contributing to the expansion of the oligonucleotide synthesis market?
The escalation of chronic diseases is likely to drive the expansion of the oligonucleotide synthesis market. Chronic diseases, which refer to ailments that persist longer than a year and necessitate ongoing medical supervision, can progressively deteriorate over time. Oligonucleotides can manipulate the gene expression responsible for these chronic diseases through different strategies. They can focus on mRNA, pre-mRNA, or non-coding RNA to change splicing events, induce breakdown, or disrupt protein translation. For example, as per the World Health Organization in September 2022, a Switzerland-based branch of the United Nations, there were 41 million fatalities, accounting for 74% of deaths annually worldwide due to non-communicable diseases or chronic diseases. Specific statistics included 17.9 million deaths due to cardiovascular diseases, 9.3 million due to cancer, 4.1 million from chronic respiratory diseases, and 2.0 million from diabetes. Consequently, the increasing frequency of chronic and rare diseases is fueling the growth of the oligonucleotide synthesis market.

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What growth opportunities are expected to drive the oligonucleotide synthesis market's CAGR through 2034?
There has been a swift expansion of the oligonucleotide synthesis market in the last few years. Its size is projected to increase from $10.33 billion in 2024 to $11.94 billion in 2025, implying a compound annual growth rate (CAGR) of 15.6%. Factors such as advancement in biomedical research, therapeutic development, innovations in biotechnology, genomic studies, and the rise in DNA technologies have contributed to the growth during the historical period.

The forecast predicts a quick expansion of the oligonucleotide synthesis market in the near future, with an estimated worth of $22.29 billion in 2029 and a compound annual growth rate (CAGR) of 16.9%. Growth factors during this period are predicted to be new diagnostic tools, RNA interference (RNAi) therapies, advancements in regenerative medicine, applications of nanotechnology, and progress in gene editing. The predicted trends for this period include focused drug development, inventive delivery systems, automated synthesis, CRISPR-cas technology, and next-generation sequencing (NGS).

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What are the emerging trends shaping the future of the oligonucleotide synthesis market?
The primary trend seen in the oligonucleotide synthesis market is product innovation. To keep up their market position, leading enterprises are coming up with cutting-edge products. The Ansa Clonal DNA and Ansa DNA Fragments,for instance, were launched in July 2024 by Ansa Biotechnologies, Inc., a firm which specializes in complex DNA manufacturing from the US. Ansa Clonal DNA can generate error-free DNA sequences up to 600 base pairs long, eliminating the need for assembly and promising unparalleled accuracy for intricate synthetic biology projects. This guarantees ready-to-use, flawless DNA sequences, which researchers find highly reliable. The Ansa DNA Fragments are designed to present sequence-verified linear double-stranded DNA fragments up to 600 base pairs, catering to a wide array of research applications. Thanks to their innovative enzymatic synthesis method, Ansa can consistently create complex DNA constructs like repeats and secondary structures with great precision.

Which growth-oriented segments of the oligonucleotide synthesis market are leading the industry's development?
The oligonucleotide synthesis market covered in this report is segmented -

1) By Type: Custom Oligos, Predesigned Oligos
2) By Product Type: Oligonucleotides, Reagents, Equipment, Services, Purification, Modification
3) By Application: Therapeutic Applications, Research Applications, Diagnostic Applications

Subsegments:
1) By Custom Oligos: Long Oligonucleotides, Short Oligonucleotides, Modified Oligonucleotides
2) By Predesigned Oligos: Gene-Specific Oligos, Probe Oligos, Primers For PCR And RT-PCR

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What regions are leading the charge in the oligonucleotide synthesis market?
North America was the largest region in the oligonucleotide synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the oligonucleotide synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What companies are at the forefront of innovation in the oligonucleotide synthesis market?
Major companies operating in the oligonucleotide synthesis market include Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, GE HealthCare Technologies Inc., Eurofins Scientific SE, Agilent Technologies Inc., Nitto Denko Avecia Inc., Alnylam Pharmaceuticals Inc., Maravai Life Sciences, LGC Limited, Ionis Pharmaceuticals Inc., GenScript Inc., Ajinomoto Bio-Pharma Services, Sarepta Therapeutics Inc., Integrated DNA Technologies Inc., Twist Bioscience Corporation, Eurogentec SA, Kaneka Eurogentec S.A., Biocomma Limited, Bio-Synthesis Inc., TriLink BioTechnologies Incorporated, Generi Biotech s.r.o., ATDBio Ltd., BioAutomation Corporation, Biolegio B.V., Dharmacon Research Inc.

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What Is Covered In The Oligonucleotide Synthesis Global Market Report?

• Market Size Forecast: Examine the oligonucleotide synthesis market size across key regions, countries, product categories, and applications.
• Segmentation Insights: Identify and classify subsegments within the oligonucleotide synthesis market for a structured understanding.
• Key Players Overview: Analyze major players in the oligonucleotide synthesis market, including their market value, share, and competitive positioning.
• Growth Trends Exploration: Assess individual growth patterns and future opportunities in the oligonucleotide synthesis market.
• Segment Contributions: Evaluate how different segments drive overall growth in the oligonucleotide synthesis market.
• Growth Factors: Highlight key drivers and opportunities influencing the expansion of the oligonucleotide synthesis market.
• Industry Challenges: Identify potential risks and obstacles affecting the oligonucleotide synthesis market.
• Competitive Landscape: Review strategic developments in the oligonucleotide synthesis market, including expansions, agreements, and new product launches.

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