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The Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Future Trends and Scope Analysis Report
According to the latest market research report by InsightAce Analytic, the Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing market size was valued at US$ 41.8 Mllion in 2021, and it is expected to reach US$ 635.9 Million in 2028, record a promising CAGR of 47.54% from 2021 to 2030.
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In recent decades, microbiome research has advanced and emerged as a promising area for developing novel medical treatments. In addition to human health, microbiome research provides a foundation for many applications. The microbiome, which consists of microorganisms that inhabit and reside in the human body, is essential for virtually every aspect of human health. Increasing evidence suggests that a new class of live biotherapeutics based on modified microorganisms could treat specific disease pathways, highlighting the significance of microorganisms in human health and various diseases. Live Biotherapeutic Products (LBP), also known as bugs-as-drugs, is a new therapeutic modality developed by biotech and pharmaceutical companies worldwide. Live Biotherapeutic Products (LBP) (s), a new class of live-bacteria-based medications, can potentially treat serious diseases. Between 2010 and 2019, the number of new pharmaceuticals certified for sale increased by 60%, reaching a maximum of 59 in 2018.
Increasing R&D efforts and a growing pipeline of microbiome-targeting therapies that treat a broad spectrum of grievous diseases are expected to drive market growth over the forecast period. Innovation and technological advancements in new drug development and clinical trial activities for the treatment of illness are driving market expansion. During the forecast period, the increased R&D budget for drug development and the rise in government funding are anticipated to generate significant growth opportunities. The COVID-19 pandemic is expected to boost the global contract manufacturing market for Live Biotherapeutic Products (LBP) and microbiomes. The COVID-19 outbreak has caused numerous disruptions in the healthcare industry and significantly impacted the execution of clinical trials worldwide. However, other significant market factors are specific requirements for developing engineered live bacterial therapeutics, a lack of infrastructure, and uncertainties related to product approval and regulatory review.
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The prominent players in the Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing industry include:
Quay Pharmaceuticals, Cobra Biologics Limited, Cerbios-Pharma SA, List Biological Labs, Inc., Arranta Bio, BacThera, Luina Bio Pty Ltd, 4D pharma plc, Paras Biopharmaceuticals Finland Oy, Capsugel, Deerland Probiotics & Enzymes, Paragon Bioservices, UAS Labs, Biose, Cobra Biologics, Cerbios, Inpac Probiotics, BJP Laboratories, S-Biomedic, Meteoric Biopharmaceuticals, BiomX, Universal Stabilization Technologies, Assembly Biosciences, Wacker Biotech, Chung Mei Pharmaceutical and Other Prominent Players.
Key Industry Developments from Leading Players:
• In Nov 2021, Bacthera and Seres Therapeutics announced a collaboration to manufacture SER-109, Seres' lead product candidate for recurrent Clostridioides difficile infection (CDI). Under the terms of the agreement, Bacteria is establishing a dedicated facility for commercial manufacturing in its new Microbiome Center of Excellence, a manufacturing site dedicated to the production of s located on Lonza's Ibex campus in Visp, Switzerland. The agreement between Bacteria and Seres Therapeutics aims to expand upon Seres' initial commercial manufacturing supply chain
• In May 2021, Bacthera's drug product facility in Basel, Switzerland, and by the Danish Medicines Agency at Bacthera's drug substance facility in Hørsholm, Denmark, both facilities had been granted manufacturing licenses by the respective national health authorities. The permit will allow the Company to fulfill the scope of bringing innovative Live Biotherapeutic Products (LBP) to patients with unmet medical needs
• In Nov 2019, Arranta Bio has received an US$82 million funding round and a strategic partnership with Thermo Fisher Scientific.Through this partnersship with Thermo Fisher, Arranta has access to the company's a wide range of product portfolio and services and provided materials to Thermo Fisher for use in gene therapy production
• In Oct 2019, 4D pharma plc announced research collaboration and option to license agreement with MSD, the tradename of Merck & Co., Inc. to discover and develop Live Biotherapeutics ("s") for vaccines. Through this agreement, 4D's proprietary MicroRx platform will be paired with MSD's expertise in developing and commercializing novel vaccines to discover and develop s as vaccines in up to three undisclosed indications
• In April 2019, Chr. Hansen Holding A/S and Lonza AG equally shared approximately €90m ($101.5m) to establish a CDMO (contract development and manufacturing organization) for biotherapeutic products. The investment was in two phases, bagan with an update to Lonza's existing facilities in Hørsholm, Denmark, for cGMP production of drug substances (anaerobic bacteria). It also equiped new facilities in Basel, Switzerland, for drug product development and manufacturing.
Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Regional Analysis:
North America dominated the global market, contributing for the majority share of the market in 2021. On account of rising R&D spending and the high adoption of new technology, the Region is likely to lead the global market during the forecast period. Intense research and a commercial base for live biotherapeutic and microbiome products and the presence of biopharmaceutical Contract manufacturers are factors contributing to the regional market's growth. Asia Pacific is also projected to expand at the significant growth over the forecast period. Due to key market players' increasing research and development activities, Europe is expected to witness significant growth during the forecast period.
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The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Segments
The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2022 to 2030 based on Product Manufactured
• APIs
• FDFs
The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2022 to 2030 based on Type of Formulation
• Solid Formulations
• Oral Liquids
• Injectables
• Others
The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2022 to 2030 based on Scale of Operation
• Preclinical Scale Operations
• Clinical Scale Operations
• Commercial Scale Operations
The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2022 to 2030 based on Company Size
• Small-sized Companies
• Mid-sized Companies
• Large Companies
The Global Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2022 to 2030 based on Region
• Europe
• North America
• Latin America
• Asia Pacific
• Middle East & Africa
North America Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates Revenue (US$ Million) by Country, 2022 to 2030
• U.S.
• Canada
Europe Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates Revenue (US$ Million) by Country, 2022 to 2030
• Germany
• France
• Italy
• Spain
• Russia
• Rest of Europe
Asia Pacific Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates Revenue (US$ Million) by Country, 2022 to 2030
• India
• China
• Japan
• South Korea
• Australia & New Zealand
Latin America Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates Revenue (US$ Million) by Country, 2022 to 2030
• Brazil
• Mexico
• Rest of Latin America
The Middle East & Africa Live Biotherapeutic Products (LBP) And Microbiome Contract Manufacturing Market Estimates Revenue (US$ Million) by Country, 2022 to 2030
• South Africa
• GCC Countries
• Rest of the Middle East & Africa
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