Non-covid mRNA Vaccine and Therapeutics Market Exclusive Report on Current Trends and Future Insights

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Non-covid mRNA Vaccine and Therapeutics Market Size, Share & Trends Analysis Report By Product Type (mRNA Therapeutic, mRNA Vaccines), By Therapeutic Area (Infectious Diseases, Oncological Disorders, Other Disorders), By Route of Administration (Intravenous, Intramuscular, Intranasal, Others)- Market Outlook and Industry Analysis 2031"

The Global Non-covid mRNA Vaccine and Therapeutics Market is valued at US$ 370.0 Mn in 2024, and it is expected to reach US$ 1,684.80 Mn by 2031, with a CAGR of 24.20% during the forecast period of 2024-2031.

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Advances in mRNA technology in medical therapeutics and vaccines are now being made at extraordinary speeds, setting it on track to expand the non-covid mRNA vaccine and therapeutics market. This new field employs synthetic mRNA to instruct cells to make the protein, which may be used for treating or preventing diseases such as infectious diseases, cancers, and some genetic disorders. Unlike the traditional vaccines that make pathogens weak, mRNA vaccines program cells inside the human body to further create an immune response. This is an attribute that will ensure mRNA-based platforms easily be designed and react toward emerging newly acquired health issues as well; therefore, mRNA is a versatile tool for disease prevention and therapy.
Application fields are immense for non-covid mRNA therapeutics. mRNA vaccines are under development for several infectious diseases: influenza, HIV, and Zika-to stimulate a strong immunity. Similarly, for cancer therapy, mRNA vaccines encoding tumor-specific antigens are introduced to help attack and destroy cancer cells; such vaccines are individually being developed based on individual tumor profiles. In the case of genetic diseases, mRNA can offer cellular instructions for generating missing or otherwise improperly functioning proteins. In such a way, the relevance of the technology revolves around acceleration of production, scalability, and proven safety and effectiveness as one of the most important solutions for addressing unmet medical needs in various therapeutic areas.

List of Prominent Players in the Non-covid mRNA Vaccine and Therapeutics Market:
• CureVac
• Anima Biotech
• Arcturus Therapeutics
• BioNTech (Pfizer)
• eFFECTOR Therapeutics, Inc.
• eTheRNA
• Ethris (AstraZeneca)
• H3 Biomedicine Inc. (Eisai Inc.)
• In-Cell-Art
• Ionis Pharmaceuticals, Inc.
• Kernal Biologics
• Moderna
• RNAimmune (Sirnaomics)
• Silence Therapeutics
• Skyhawk Therapeutics, Inc.
• Stemirna Therapeutics Co., Ltd.
• Tiba Biotechnology
• Translate Bio Sanofi)
• Ziphius Therapeutics NV

Market Dynamics:
Drivers:
Factors such as improvement in technology, stability, delivery, and efficacy through innovations like lipid nanoparticles fuel the non-covid mRNA vaccine and therapeutics market. The potential area of application also remains enormous, from infectious disease vaccines to personalized therapy for cancers and treatments of genetic disorders. Advantages in mRNA development and scalability on a large scale, showcased in response to the COVID-19 pandemic, ensure fast, high-volume production. Indeed, with a favorable safety profile and increased investment following the success of COVID vaccines, the field is advancing at speed. Sanofi's acquisition of Translate Bio further strengthens its mRNA Center of Excellence as an engine for innovation across vaccines, immunology, oncology, and rare diseases.

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Challenges:
The non-covid mRNA vaccine and therapeutics market faces key challenges that can hinder production efficiency. Uncoordinated processes involving multiple vendors lead to inefficiencies and delays, particularly for smaller companies with limited resources. Additionally, limited access to GMP-grade raw materials creates bottlenecks, affecting production timelines. The complexity of manufacturing, especially in purifying and producing uncontaminated mRNA, further complicates efforts, making the process time-consuming and challenging to manage effectively.

Regional Trends:
North America is propelled by its strong infrastructure in research and development, combined with leading pharmaceutical companies, biotech firms, and well-established academic institutions to an enabler environment. That ecosystem not only incites innovation but also attracts investments and cooperations, as seen with Moderna's mRNA vaccine, mRESVIA, which, for example, has been approved by the U.S. FDA to protect adults of 60 years or older from severe RSV-related respiratory disease. More importantly, investments by the public and private sectors in a very enabling regulatory environment for speeding up approvals also tell one why the region is at the cutting edge of the development of mRNA technology.

Recent Developments:
• In Jan 2023, Moderna, Inc. announced a definitive agreement to acquire OriCiro for $85 million. This acquisition provides Moderna with advanced tools for cell-free synthesis and amplification of plasmid DNA, a crucial component in the mRNA manufacturing process.
• In Aug 2021, Sanofi entered into a definitive agreement to acquire Translate Bio, a clinical-stage mRNA therapeutics company, for $38.00 per share in cash, totaling approximately $3.2 billion. Both companies' Boards of Directors have unanimously approved the transaction, aiming to accelerate Sanofi's development of mRNA-based therapeutics and vaccines.

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Segmentation of Non-covid mRNA Vaccine and Therapeutics Market-
Non-covid mRNA Vaccine and Therapeutics Market- By Product Type
• mRNA Therapeutic
• mRNA Vaccines
Non-covid mRNA Vaccine and Therapeutics Market- By Therapeutic Area
• Infectious Diseases
o Influenza
o Respiratory Syncytial Virus (RSV)
o Cytomegalovirus
o Others
• Oncological Disorders
• Other Disorders
Non-covid mRNA Vaccine and Therapeutics Market- By Route of Administration
• Intravenous
• Intramuscular
• Intranasal
• Others
Non-covid mRNA Vaccine and Therapeutics Market- By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa

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