Ascites Therapeutics Market Size in the 7MM is expected to grow by 2034, according to the DelveInsight

DelveInsight's "Ascites Market Insights, Epidemiology and Market Forecast - 2034" report delivers an in-depth understanding of the Ascites, historical and forecasted epidemiology as well as the Ascites market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

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Key Takeaways from the Ascites Market Report
• In January 2025:- Versantis AG- A Phase 2, multi-center, randomized, controlled, open-label study to evaluate the effects of the intraperitoneal, liposomal formulation VS-01 in patients with an acute episode of hepatic and/or extrahepatic organ dysfunctions and failures in the presence of liver cirrhosis (Acute-on-Chronic Liver Failure, ACLF) and accumulation of fluid in the abdominal cavity (ascites).
• In January 2025:- Centre Hospitalier Universitaire de Besancon- A Multicenter, Double-blind, Placebo-controlled Randomized Clinical Trial Comparing Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites : Using or Not Using Rifaximin
• It is estimated that the Ascites treatment market will experience significant changes during the forecast period of 2024-2034, owing to the launch of new therapies that are in clinical development.
• DelveInsight analysis indicates that in 2023, the US had approximately 153 thousand cases of Ascites due to Cirrhosis, accounting for the largest share in the 7MM.
• DelveInsight's analysis revealed that in Japan during 2023, there were 5,355 instances of Grade I ascites attributed to cirrhosis. Additionally, more severe cases of Grade II and III ascites were recorded at 24,394 cases each in the same year.
• The leading Ascites Companies such as Grifols Therapeutics LLC, Sanofi, Regeneron Pharmaceuticals, Sequana Medical N.V, Protgen Ltd, Healthgen Biotechnology Corp, Sichuan Clover Biopharmaceuticals Inc, Movetis, BioVie Inc., Ocelot Bio Inc, Novartis, and others.
• Promising Ascites Therapies such as Recombinant Human Serum Albumin, M701, paracentesis, OrsHSA, VS-01, Ambrisentan, Terlipressin, and others.

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Ascites Epidemiology Segmentation in the 7MM
• Number of Ascites Cases by Malignancies
• Number of Ascites Cases due to Cirrhosis
• Severity-specific Cases of Ascites due to Cirrhosis
• Refractory Ascites Patients with Cirrhosis

Ascites Treatment Market Landscape
The treatment landscape of ascites due to cirrhosis include diuretics, paracentesis, insertion of a transjugular intrahepatic portosystemic shunt (TIPS), as well as managing complications to ascites such as spontaneous bacterial peritonitis (SBP). Mild and moderate ascites due to liver cirrhosis can be treated with dietary sodium restriction, treatment of the underlying disorder, fluid restriction, use of diuretics, and use of therapeutic paracentesis.

Ascites Emerging Drugs
• PHIN-214: PharmaIN
PharmaIN has advanced PHIN-214, a novel compound being developed for treating refractory ascites due to advanced liver cirrhosis, into a US Phase Ib clinical trial in cirrhotic patients. The therapeutic approach of PHIN-214 therapy is to shut down the RAAS signaling pathway, thereby halting the retention of excess salt and water by the kidneys and ending ascites fluid production.

• OCE-205: Ocelot Bio
Ocelot Bio is developing OCE-205, an investigational therapy to transform the treatment of end-stage liver disease. The company is also developing OCE-205 for the treatment of ascites, a complication of ESLD-induced portal hypertension that leads to the accumulation of fluid in the peritoneal cavity. Currently, the company is conducting a Phase II multi-center, randomized, placebo-controlled, double-blind, adaptive dose-ranging study to assess the safety and efficacy of intravenous OCE-205 in adults diagnosed with cirrhosis with ascites who have developed hepatorenal syndrome-acute kidney injury, and a Phase I clinical trial of ascites.

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Ascites Drugs Market
The Ascites market for drugs targeting ascites is notably constrained. While certain treatments provide symptomatic relief, there is a significant lack of approved drugs addressing the condition's underlying causes. This scarcity of targeted treatments reflects a major challenge in effectively managing the diverse manifestations of ascites, indicating a substantial need for innovative solutions and advancements in drug development for more comprehensive care.

Ascites Market Outlook
Sodium restriction and diuretics are the mainstays of treatment for patients with ascites due to portal hypertension, but patients with low Serum Ascites Albumin Gradient (SAAG) (less than 1.1 g/dL) ascites do not respond well to these measures, except those with nephrotic syndrome. Tolvaptan, a novel aquaporin modulator, was made available in Japan in 2013 for the treatment of patients with refractory ascites due to cirrhosis. However, it is not approved in Japan for the treatment of ascites.

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Scope of the Ascites Market Report
• Coverage- 7MM
• Study Period- 2020-2034
• Ascites Companies- as Grifols Therapeutics LLC, Sanofi, Regeneron Pharmaceuticals, Sequana Medical N.V, Protgen Ltd, Healthgen Biotechnology Corp, Sichuan Clover Biopharmaceuticals Inc, Movetis, BioVie Inc., Ocelot Bio Inc, Novartis, and others.
• Ascites Therapies- Recombinant Human Serum Albumin, M701, paracentesis, OrsHSA, VS-01, Ambrisentan, Terlipressin, and others.
• Ascites Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
• Ascites Unmet Needs, KOL's views, Analyst's views, Ascites Market Access and Reimbursement

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Table of Content
1. Key Insights
2. Ascites Market Report Introduction
3. Executive Summary
4. Ascites Market Overview at a Glance
5 Key Events
6 Ascites Epidemiology and Market Forecast Methodology
7 Ascites Disease Background and Overview
8 Ascites Epidemiology and Patient Population
9 Patient Journey
10 Ascites Emerging Therapies
11 Ascites: Seven Major Market Analysis
12 Ascites Unmet Needs
13 Ascites SWOT Analysis
14 KOL Views
15 Ascites Market Access and Reimbursement
16 Appendix
17 DelveInsight Capabilities
18 Disclaimer
19 About DelveInsight

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