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Protein Expression Market Set to Soar Amid Growing Biopharma Production

01-23-2025 02:34 PM CET | Health & Medicine

Press release from: Emergen Research

Protein Expression Market

Protein Expression Market

The protein expression market is expected to grow from an estimated USD 3514.5 million in 2024 to USD 8702.8 million in 2033, at a CAGR of 10.60%. The protein expression market is poised for significant growth, driven by increased production capacities within the biopharmaceutical industry. With biosimilars gaining traction in treating rare diseases, autoimmune disorders, and cancer, their cost advantages and regulatory support are fueling demand. The COVID-19 pandemic also spurred the expansion of vaccine manufacturing facilities, further boosting the market.

Key Drivers:

Biopharmaceutical Expansion: Companies are ramping up production to meet the rising demand for biosimilars. For example, Thermo Fisher Scientific Inc. expanded its facilities in Cincinnati, Ohio, and Bend, Oregon, in October 2024 to support oral drug development.

Demand for Biologics: The increasing need for biologics, such as monoclonal antibodies and antibody-drug conjugates, is driving market growth. In 2023, the US FDA approved 17 new biologics, including 12 monoclonal antibodies.

Emerging Economies: Nations like China, India, Brazil, and Mexico are experiencing growth in the biopharmaceutical sector due to public and private investments, making them attractive markets for protein expression systems.

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Market Restraints: Efficiency issues and high production costs pose challenges. Bacterial systems, though cost-effective, can lead to difficult-to-purify protein clumps. Yeast and mammalian systems, while effective, face high production costs and lower expression levels. Plant-based systems are limited by concerns over gene and protein spread into the food chain.

Segment Insights:

Prokaryotic Systems: Leading the market with features like cost-effective and large-scale recombinant protein production.

Mammalian Systems: Expected to grow at the highest rate, driven by pharmaceutical companies using these systems for protein production. Innovations like ProteoGenix's XtenCHOTM Transient Expression System are enhancing protein yields and speeding up drug screening processes.

The protein expression market is on an upward trajectory, supported by the biopharmaceutical industry's expansion and increasing demand for biologics. Despite some challenges, the market holds significant growth potential, particularly in emerging economies.

Protein Expression Top Companies and Competitive Landscape

Agilent Technologies, Inc., Bio-Rad Laboratories, Thermo Fisher Scientific, Inc., and Merck Millipore are some key companies to watch out for innovation in the protein expression market. Key players operating in the market are adopting various strategies to increase their market presence and expand their product portfolio.

In April 2024, Expression Systems collaborated with Thomson to demonstrate how Expression Systems' ESF AdvanCD cell culture medium and Thomson's Optimum Growth flasks may improve protein output. This collaboration showed steady cell growth and high expression levels in a range of flask sizes and culture volumes, suggesting a dependable and expandable production platform.

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Some of the key companies in the global Protein Expression Market include:

Agilent Technologies, Inc.

Bio-Rad Laboratories

Thermo Fisher Scientific, Inc.

Merck Millipore

New England BioLabs, Inc.

Promega Corporation

QIAGEN

Takara Bio, Inc.

Oxford Expression Technologies

Lucigen Corporation

Protein Expression Latest Industry Updates

In June 2024, Thermo Fisher Scientific, Inc. launched the Thermo Scientific Stellar mass spectrometer (MS), which supports translational omics research with high throughput operations.

In August 2024, Merck KGaA acquired Mirus Bio to integrate its cutting-edge transfection reagents into its bioprocessing portfolio and enhance its capacity to manufacture viral vectors.

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Protein Expression Market Segmentation Analysis

Systems Outlook (Revenue, USD Million; 2020-2033)

Prokaryotic

Insect Cell

Yeast

Mammalian Cell

Others

Product Outlook (Revenue, USD Million; 2020-2033)

Reagents

Expression Vectors

Instruments

Competent Cells

Services

Application Outlook (Revenue, USD Million; 2020-2033)

Research

Therapeutic

Industrial

End User Outlook (Revenue, USD Million; 2020-2033)

Contract Research Organizations

Pharmaceutical and Biotechnological Companies

Academic Research

Others

Regional Outlook (Revenue, USD Million; 2020-2033)

North America

United States

Canada

Mexico

Europe

Germany

France

United Kingdom

Italy

Spain

Benelux

Rest of Europe

Asia-Pacific

China

India

Japan

South Korea

Rest of Asia-Pacific

Latin America

Brazil

Rest of Latin America

Middle East and Africa

Saudi Arabia

UAE

South Africa

Turkey

Rest of MEA

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Read Similar Reports By Emergen Research:

Protein Expression Market Size @ https://www.emergenresearch.com/industry-report/protein-expression-market/market-size

Protein Expression Market Share @ https://www.emergenresearch.com/industry-report/protein-expression-market/market-share

Protein Expression Market Trends @ https://www.emergenresearch.com/industry-report/protein-expression-market/market-trends

Protein Expression Regional Market Demand @ https://www.emergenresearch.com/industry-report/protein-expression-market/regional-market-demand

Protein Expression Market Analysis @ https://www.emergenresearch.com/industry-report/protein-expression-market/market-analysis

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Emergen Research | Web: www.emergenresearch.com
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Emergen Research is a market research and consulting company that provides syndicated research reports, customized research reports, and consulting services. Our solutions purely focus on your purpose to locate, target, and analyse consumer behavior shifts across demographics, across industries, and help clients make smarter business decisions. We offer market intelligence studies ensuring relevant and fact-based research across multiple industries, including Healthcare, Touch Points, Chemicals, Types, and Energy. We consistently update our research offerings to ensure our clients are aware of the latest trends existent in the market. Emergen Research has a strong base of experienced analysts from varied areas of expertise. Our industry experience and ability to develop a concrete solution to any research problems provides our clients with the ability to secure an edge over their respective competitors.

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