Press release
Acquisition of Kadima Neuropsychiatry Institute for CNS & Psychedelic Research Planned; New Drug Application for Treatment of Suicidal Depression: NRx Pharmaceuticals NRXP
$NRXP IS Aiming to be the First FDA-Approved Medication to Treat Suicidal Depression- Developing NRX-101, an FDA-Designated Investigational Breakthrough Therapy for Suicidal Treatment-Resistant Bipolar Depression and Chronic Pain.
- Designed to Help Address the Needs of Over 13 Million Americans who Seriously Consider Suicide Each Year (CDC).
- Kadima Neuropsychiatry Institute Targeted as First Acquisition for HOPE Subsidiary International Network of Interventional Psychiatry Clinics.
- Kadima is a Leading Investigative Site for CNS and Psychedelic Research.
- Completion of NDA Filing Expected in First Quarter of 2025
- Plans to Participate in J.P. Morgan Healthcare Conference on January 13-16, 2025, in San Francisco, CA.
NRx Pharmaceuticals, Inc. (Nasdaq: NRXP) is a clinical-stage biopharmaceutical company developing therapeutics based on its NMDA platform for the treatment of central nervous system disorders, specifically suicidal bipolar depression, chronic pain and PTSD. NRXP is developing NRX-101, an FDA-designated investigational Breakthrough Therapy for suicidal treatment-resistant bipolar depression and chronic pain
NRXP has partnered with Alvogen Pharmaceuticals around the development and marketing of NRX-101 for the treatment of suicidal bipolar depression. NRX-101 additionally has potential to act as a non-opioid treatment for chronic pain, as well as a treatment for complicated UTI.
NRXP is working on a New Drug Application for NRX-100 (IV ketamine) in the treatment of suicidal depression, based on results of well-controlled clinical trials conducted under the auspices of the US National Institutes of Health and newly obtained data from French health authorities, licensed under a data sharing agreement. NRXP was awarded Fast Track Designation for development of ketamine (NRX-100) by the US FDA as part of a protocol to treat patients with acute suicidality.
Intravenous ketamine is widely accepted as a standard of care for acute treatment of suicidal depression, in the absence of an FDA-labeled product; the only treatment currently approved by the FDA is electroconvulsive therapy (ECT). According to the CDC, 3.8 million Americans make a plan for suicide each year. This represents a $3-5 billion market at expected pricing. Based on the data in the trials referenced above, the Company's regulatory counsel encouraged the Company to file an NDA for suicidal depression for NRX-100.
Kadima Neuropsychiatry Institute Expected First Acquisition for HOPE Subsidiary International Network of Interventional Psychiatry Clinics
On January 2nd NRXP announced the planned acquisition of the Kadima Neuropsychiatry Institute of La Jolla, CA, per the previously announced Letter of Intent, for the Company's HOPE subsidiary network. Kadima is expected to serve as the flagship clinic for HOPE's planned international network of interventional psychiatry clinics, designed to provide advanced treatments for debilitating diseases such as depression, anxiety and PTSD.
Kadima is one of the world's premier interventional psychiatry clinics and was among the first to introduce Ketamine Therapy for Central Nervous System (CNS) disorders at scale in the clinic setting. The clinic offers a full range of cutting-edge treatments for suicidal depression, anxiety, Post Traumatic Stress Disorder (PTSD) and other CNS disorders. Those treatment options include Ketamine Therapy, Spravato Registered (nasal esketamine), Transcranial Magnetic Stimulation as well as medication management.
Kadima also has a robust research division and is a leading investigative site for innovative CNS treatments, specializing in psychedelic research, for which it has served as a leading site in nearly all major clinical trials in this area. Kadima has contracts in place with the US Department of Veterans Affairs and also treats active-duty military personnel in the US Department of Defense under Tricare and other treatment programs.
Kadima's founder and CEO, Prof. David Feifel, MD PHD, has been a pioneer and international thought leader for advanced interventional treatment of psychiatric disorders such as depression, anxiety, PTSD and related disorders for more than three decades. Among other things, he is a co-author on a recent landmark expert consensus paper for treating depression with TMS, endorsed by three leading organizations in the field (ref). He also established the first clinical program to use subanesthetic dose ketamine infusions for neuropsychiatric disorders at UC San Diego, where he is currently Professor Emeritus of Psychiatry. His 150 peer-reviewed publications and several patents have provided global thought leadership on advanced approaches to treating psychiatric conditions, including integration of medicines like ketamine with neuromodulation such as, Transcranial Magnetic Stimulation and Digital Therapeutics. Kadima's experience will guide the growing network of NRXP HOPE Therapeutics clinics to an integrated, multi-modal approach to treating suicidal depression, anxiety and PTSD that is far more effective than ketamine alone.
Upon consummation of the proposed acquisition, Dr. Feifel will serve as NRXP HOPE's Chief Medical Innovation Officer (CMIO), focused on identifying and evaluating new developments in the treatment of CNS disorders and insuring Hope clinics are at the forefront of interventional psychiatry delivery, and leading global clinical trials to continue to advance the ability to treat these lethal diseases.
Dr. Feifel will join NRXP Chairman, Prof. Jonathan Javitt in presenting a Keynote address at the 8th Annual Neuroscience Innovation Forum during the JP Morgan Healthcare Conference in San Francisco, CA on the 12th of January 2025, and will join in meeting investors over the following week.
Initial Section of U.S. New Drug Application to the FDA for NRX-100 (IV Ketamine) for the Treatment of Suicidal Depression
On December 30th NRXP announced the transmission of first section of its New Drug Application (NDA) for NRX-100 (ketamine) for electronic filing with the U.S. Food & Drug Administration (FDA). NRX-100 was initially granted Fast Track Designation in 2017 for use in combination with NRX-101 (D-cycloserine/lurasidone) for treatment of suicidal bipolar depression. The Company is now seeking to expand the indication to include Suicidal Ideation in Major Depressive Disorder and other forms of depression, based on data from NIH- and European Government-funded trials that have been summarized on the NRXP website.
While assembly of the clinical data sections is being completed, FDA has asked the Company to submit the 1800-page manufacturing section (Module 3) of the NDA to enable immediate review prior to submission of final efficacy data and other sections of the NDA expected in the first quarter of 2025.
The NRx presentation of ketamine differs from the form of ketamine used in anesthesia in that it contains no potentially toxic preservatives and utilizes diversion-resistant packaging to enhance the traceability of a medicine known to have abuse potential.
For more information on $NRXP visit: https://www.nrxpharma.com/ and https://compasslivemedia.com/case-study/nrx-pharmaceuticals/
Disclaimer and Disclosure: www.aibrandnetwork.com
Media Contact
Company Name: NRx Pharmaceuticals, Inc.
Contact Person: Matthew Duffy, Chief Business Officer
Email: Send Email [http://www.universalpressrelease.com/?pr=acquisition-of-kadima-neuropsychiatry-institute-for-cns-psychedelic-research-planned-new-drug-application-for-treatment-of-suicidal-depression-nrx-pharmaceuticals-nrxp]
Phone: 484 254 6134
Address:1201 Orange Street Suite 600
City: Miami
State: Florida
Country: United States
Website: https://www.nrxpharma.com/
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Acquisition of Kadima Neuropsychiatry Institute for CNS & Psychedelic Research Planned; New Drug Application for Treatment of Suicidal Depression: NRx Pharmaceuticals NRXP here
News-ID: 3803071 • Views: …
More Releases from Getnews

Outlaw Horse Club Hosts Community Day in Fayetteville on October 4, 2025
Image: https://www.globalnewslines.com/uploads/2025/09/1758992064.jpg
Outlaws Horse Club Community Day
Founded in 1999 by Jody Lindsey, the Outlaw Horse Club was established to create a welcoming space for people who love horses and for families looking to bond over shared traditions. Over the past 25 years, the club has grown into more than just a horse-riding group-it has become a hub for community engagement, education, and family support.
The Outlaw Horse Club, a long-standing pillar of…

The Duct Stories Expands Services and Launches HVAC Solutions at New Winnipeg Lo …
Image: https://www.globalnewslines.com/uploads/2025/09/1758983489.jpg
The Duct Stories strengthens presence in Winnipeg by adding HVAC repairs and installations while establishing operations at Elgin Ave.
Winnipeg, MB - September 29, 2025 - Today marks a new phase of growth for The Duct Stories, as it broadens its services to include HVAC repairs and installations. The move to a modern facility on Elgin Ave signals growth and innovation for the Winnipeg-based provider. This milestone reflects the company's…

ASE-Certified Auto Repair Shop Strengthens Local Presence in Smyrna, DE
Image: https://www.globalnewslines.com/uploads/2025/09/1758982280.jpg
Pristine Motorsports Delivers Reliable, Affordable Auto Care with Advanced Equipment and Customer-First Values
SMYRNA, DE - September 29, 2025 - Pristine Motorsports, an ASE-certified auto repair facility located at 1950 S Dupont Blvd, continues to solidify its position as Smyrna's go-to destination for reliable, honest auto care. Since opening its doors in 2013, Pristine Motorsports has become known throughout Delaware for expert service, integrity-driven repairs, and over 400 glowing customer…

Repair One Tire & Auto Voted Best Auto Repair Shop in The Woodlands by Living Ma …
Image: https://www.globalnewslines.com/uploads/2025/09/1758981339.jpg
Family-Owned Business Recognized for Quality, Integrity, and Trusted Service
The Woodlands, TX - September 29, 2025 - Repair One Tire & Auto, a family-owned and operated shop, has been named Best Auto Repair Shop in The Woodlands in the Living Magazine Readers' Choice Awards. As the business celebrates more than 20 years of service, this award reinforces its reputation for honesty, professionalism, and customer-first care throughout the community.
Since opening its…
More Releases for Kadima
Actions to Remove Benzethonium Chloride from Ketamine Products in Favor of Safer …
Image: https://www.globalnewslines.com/uploads/2025/08/1754310990.jpg
$NRXP Has $7.8 Million for Clinic Acquisitions and Purchase of Kadima Neuropsychiatry Institute as Treatment Model and Leading Investigative Site for Suicidal Depression / PTSD
Actions to Remove Benzethonium Chloride from Ketamine Products in Favor of Safer and Superior Option in $750 Million Market, Projected to Reach $3.35 Billion by 2034: NRx Pharmaceuticals, Inc. (Nasdaq: NRXP)
$NRXP Has $7.8 Million for Clinic Acquisitions and Purchase of Kadima Neuropsychiatry Institute as Treatment…
$750 Million Ketamine Drug Market, Projected to Reach $3.35 Billion in 2034 Comi …
Image: https://www.globalnewslines.com/uploads/2025/06/1750751162.jpg
$NRXP Has $7.8 Million for Clinic Acquisitions and Purchase of Kadima Neuropsychiatry Institute as Treatment Model and Leading Investigative Site for Suicidal Depression / PTSD
* Developing NRX-101, an FDA-Designated Investigational Breakthrough Therapy for Suicidal Treatment-Resistant Bipolar Depression and Chronic Pain.
* Aiming to be the First FDA-Approved Medication to Treat Suicidal Depression
* Designed to Help Address the Needs of Over 13 Million Americans who Seriously…
$750 Million Market Projected to Reach $3.35 Billion Globally in 2034 for Abbrev …
Image: https://www.globalnewslines.com/uploads/2025/06/1749136787.jpg
$NRXP Has $7.8 Million in Financing for Clinic Acquisitions and Purchase of Kadima Neuropsychiatry Institute as Treatment Model and Leading Investigative Site for Suicidal Depression / PTSD
* Developing NRX-101, an FDA-Designated Investigational Breakthrough Therapy for Suicidal Treatment-Resistant Bipolar Depression and Chronic Pain.
* Aiming to be the First FDA-Approved Medication to Treat Suicidal Depression
* Designed to Help Address the Needs of Over 13 Million Americans…
$7.8 Million in New Financing for Clinic Acquisitions Supporting Purchase of Kad …
Image: https://www.globalnewslines.com/uploads/2025/05/1747323554.jpg
$NRXP Set Up for $300 Million in Milestones on Tiered Double-Digit Royalties
* Developing NRX-101, an FDA-Designated Investigational Breakthrough Therapy for Suicidal Treatment-Resistant Bipolar Depression and Chronic Pain.
* Aiming to be the First FDA-Approved Medication to Treat Suicidal Depression
* Designed to Help Address the Needs of Over 13 Million Americans who Seriously Consider Suicide Each Year (CDC).
* $7.8 Million Debt Financing to Fuel…
Plan Signed to Purchase Kadima Neuropsychiatry Institute as Clinical Treatment M …
Image: https://www.globalnewslines.com/uploads/2025/05/1747147202.jpg
$NRXP Set Up for $300 Million in Milestones on Tiered Double-Digit Royalties
* Developing NRX-101, an FDA-Designated Investigational Breakthrough Therapy for Suicidal Treatment-Resistant Bipolar Depression and Chronic Pain.
* Aiming to be the First FDA-Approved Medication to Treat Suicidal Depression
* Designed to Help Address the Needs of Over 13 Million Americans who Seriously Consider Suicide Each Year (CDC).
* Agreement to Purchase Kadima Neuropsychiatry…
Transforming Mental Health Treatments and Expanding Clinic Networks: NRx Pharmac …
Image: https://www.globalnewslines.com/uploads/2025/01/1737669812.jpg
NRx Pharmaceuticals, Inc. (Stock Symbol: NRXP), a clinical-stage biopharmaceutical leader, is at the forefront of addressing critical mental health challenges, including suicidal depression, bipolar disorder, and PTSD. Through groundbreaking therapeutics and strategic investments, the company aims to revolutionize care for millions while delivering significant returns for investors.
A Breakthrough in Mental Health Treatment
NRX-101, the company's flagship product, is an FDA-designated investigational Breakthrough Therapy targeting suicidal treatment-resistant bipolar depression and chronic…