Cancer Cachexia Pipeline Therapeutics Assessment Report 2024 (Updated)

DelveInsight's, "Cancer Cachexia Pipeline Insight 2024" report provides comprehensive insights about 12+ companies and 15+ pipeline drugs in Cancer Cachexia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Explore our latest breakthroughs in Cancer Cachexia Research. Learn more about our innovative pipeline today! @ Cancer Cachexia Pipeline Outlook- https://www.delveinsight.com/sample-request/cancer-cachexia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the Cancer Cachexia Pipeline Report
• In November 2024:- AVEO Pharmaceuticals Inc.- This open label ascending dose study is designed to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of AV-380 in metastatic cancer patients with Cachexia. AV-380 is an immunoglobulin (Ig) G1 monoclonal antibody (mAb) intended to bind circulating human growth differentiation factor 15 (GDF-15), a cytokine involved in cancer-induced cachexia.
• DelveInsight's Cancer Cachexia pipeline report depicts a robust space with 12+ active players working to develop 15+ pipeline therapies for Cancer Cachexia treatment.
• The leading Cancer Cachexia Companies such as Actimed Therapeutics Ltd, Pfizer, AVEO Pharmaceuticals, NGM Biopharmaceuticals, Endevica Bio, CSPC Pharmaceutical Group Limited, Caelus Health, and others.
• Promising Cancer Cachexia Therapies such as AV-380, SAT-003, MS-20, Ponsegromab, Pancrelipase, and others.

Stay informed about the cutting-edge advancements in Cancer Cachexia treatments. Download for updates and be a part of the revolution in care @ Cancer Cachexia Clinical Trials Assessment- https://www.delveinsight.com/sample-request/cancer-cachexia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Cancer Cachexia Emerging Drugs Profile

• ACM-001.1: Actimed Therapeutics Ltd
S-pindolol has been described as an anabolic/catabolic transforming agent, or ACTA. S-pindolol (ACM-001) is an anabolic/catabolic transforming agent with a multifunctional effect on three key pharmacological targets relevant for cancer cachexia: (1) Reduction of catabolism by β-1 receptor antagonism, (2) Increased anabolism and muscle growth, through partial β2 receptor agonism, (3) Improvement in appetite and fatigue via central 5-HT1a antagonism. Currently, the drug is in Phase II/III stage of its clinical trial for the treatment of Cancer Cachexia.

• Ponsegromab: Pfizer
It is a monoclonal antibody directed against the human growth differentiation factor 15 (GDF15; MIC-1), with potential anti-cachexia activity. Upon administration, ponsegromab targets and binds to GDF15, thereby preventing the binding of GDF15 to its receptor glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL) and blocking GDF15/GFRAL-mediated signaling. This may abrogate loss of appetite and uncontrolled weight loss associated with high serum levels of GDF15. GDF15, a stress response cytokine and divergent member of the transforming growth factor beta (TGF-beta) superfamily, plays a key role in the regulation of body weight through central mechanisms. Currently, the drug is in Phase II stage of its clinical trial for the treatment of Cancer Cachexia.

• AV-380: AVEO Pharmaceuticals, Inc.
AV-380 is AVEO's first-in-class, potent, humanized inhibitory IgG1 antibody targeting growth differentiation factor 15 (GDF15). GDF15 is a pro-inflammatory cytokine whose elevated circulating levels have been correlated with cachexia in cachectic cancer patients and several animal models of cancer cachexia. Current evidence suggests that a pro-inflammatory state may be responsible for many of the symptoms associated with cachexia, a complex metabolic syndrome characterized by malnutrition and severe involuntary weight loss due to the loss of muscle and fat tissue, as well as the clinical manifestation of anemia, inflammation and suppression of immune functions. Currently, the drug is in the Phase I stage of development to treat Cancer Cachexia.

Learn more about Cancer Cachexia Drugs opportunities in our groundbreaking Cancer Cachexia Research and development projects @ Cancer Cachexia Unmet Needs- https://www.delveinsight.com/sample-request/cancer-cachexia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Cancer Cachexia Companies
Actimed Therapeutics Ltd, Pfizer, AVEO Pharmaceuticals, NGM Biopharmaceuticals, Endevica Bio, CSPC Pharmaceutical Group Limited, Caelus Health, and others.

Cancer Cachexia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical

Cancer Cachexia Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

Discover the latest advancements in Cancer Cachexia treatment by visiting our website. Stay informed about how we're transforming the future of disease @ Cancer Cachexia Market Drivers and Barriers, and Future Perspectives- https://www.delveinsight.com/sample-request/cancer-cachexia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Cancer Cachexia Pipeline Report
• Coverage- Global
• Cancer Cachexia Companies- Actimed Therapeutics Ltd, Pfizer, AVEO Pharmaceuticals, NGM Biopharmaceuticals, Endevica Bio, CSPC Pharmaceutical Group Limited, Caelus Health, and others.
• Cancer Cachexia Therapies- AV-380, SAT-003, MS-20, Ponsegromab, Pancrelipase, and others.
• Cancer Cachexia Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Myelof Cancer Cachexia ibrosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

For a detailed overview of our latest research findings and future plans, read the full details of Cancer Cachexia Pipeline on our website @ Cancer Cachexia Emerging Drugs and Companies- https://www.delveinsight.com/sample-request/cancer-cachexia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Cancer Cachexia: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Cancer Cachexia- DelveInsight's Analytical Perspective
7. Mid Stage Products (Phase II/III)
8. ACM-001.1: Actimed Therapeutics Ltd.
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. Ponsegromab: Pfizer
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. AV-380: AVEO Pharmaceuticals, Inc.
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug Name: Company Name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Cancer Cachexia Key Companies
21. Cancer Cachexia Key Products
22. Cancer Cachexia- Unmet Needs
23. Cancer Cachexia- Market Drivers and Barriers
24. Cancer Cachexia- Future Perspectives and Conclusion
25. Cancer Cachexia Analyst Views
26. Cancer Cachexia Key Companies
27. Appendix

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