Autosomal Dominant Polycystic Kidney Disease (AKPKD) Clinical Trials 2024: FDA Approvals, Medication, Treatment Market, Therapies, MOA, ROA, Companies by DelveInsight | Galapagos NV, Reata Pharma, Kadmon Pharma, Sanofi, Anakuria Therapeutics

(Albany, United States) As per DelveInsight's assessment, globally, Autosomal Dominant Polycystic Kidney Disease pipeline constitutes 12+ key companies continuously working towards developing 12+ Autosomal Dominant Polycystic Kidney Disease treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Autosomal Dominant Polycystic Kidney Disease Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Autosomal Dominant Polycystic Kidney Disease Market.
The Autosomal Dominant Polycystic Kidney Disease Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

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Some of the key takeaways from the Autosomal Dominant Polycystic Kidney Disease Pipeline Report:
• ADPKD Companies across the globe are diligently working toward developing novel Autosomal Dominant Polycystic Kidney Disease treatment therapies with a considerable amount of success over the years.
• Autosomal Dominant Polycystic Kidney Disease companies working in the treatment market are DiNAQOR AG, Poxel, AceLink Therapeutics, Regulus Therapeutics, Reata Pharmaceuticals, Sanofi, Galapagos NV, Janssen Pharmaceuticals, Xortx Therapeutics, and others, are developing therapies for the Autosomal Dominant Polycystic Kidney Disease treatment
• Emerging Autosomal Dominant Polycystic Kidney Disease therapies in the different phases of clinical trials are- DINAK 001, PXL770, AL01211, RGLS8429, Bardoxolone methyl, Tesevatinib/KD019, GLPG2737, AT-20494, XRx-008, and others are expected to have a significant impact on the Autosomal Dominant Polycystic Kidney Disease market in the coming years.
• In January 2024, Regulus Therapeutics has completed the recruitment of patients for the third cohort in the Phase Ib multiple-ascending dose (MAD) trial of RGLS8429, a prospective therapy for ADPKD. RGLS8429 aims to block miR-17 and specifically target the kidneys. This Phase Ib MAD study is structured to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of RGLS8429 in adults diagnosed with ADPKD.
• In June 2023, Regulus Therapeutics, a biopharmaceutical company, has announced the dosing of the first patient in the second cohort of a Phase 1b clinical trial for RG-8429, a potential treatment for autosomal dominant polycystic kidney disease (ADPKD). ADPKD is a genetic disorder characterized by the growth of cysts in the kidneys, leading to renal failure. The multiple ascending dose (MAD) trial aims to evaluate the safety, tolerability, and pharmacokinetics of RG-8429. The initial cohort demonstrated positive results, and the trial will now progress to higher doses. The study's findings may contribute to the development of a much-needed therapy for ADPKD patients.
• The business submitted a protocol change to the FDA and other appropriate regulatory bodies for the FALCON Phase III study of bardoxolone in patients with ADPKD in the first quarter of 2022. To discuss the protocol update, the business held a Type A meeting with the FDA.

Autosomal Dominant Polycystic Kidney Disease Overview
AKPKD stands for Autosomal Dominant Polycystic Kidney Disease. It is a genetic disorder characterized by the formation of fluid-filled cysts in the kidneys, which can lead to progressive kidney damage and impairment of renal function over time. Autosomal dominant means that only one copy of the defective gene, inherited from one parent, is sufficient to cause the condition. AKPKD is the most common inherited kidney disorder, affecting millions of people worldwide.

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Emerging Autosomal Dominant Polycystic Kidney Disease Drugs Under Different Phases of Clinical Development Include:
• DINAK 001: DiNAQOR AG
• PXL770: Poxel
• AL01211: AceLink Therapeutics
• RGLS8429: Regulus Therapeutics
• Bardoxolone methyl: ReataPharmaceuticals
• Tesevatinib/KD019: Sanofi
• GLPG2737: Galapagos NV
• AT-20494: Janssen Pharmaceuticals
• XRx-008: Xortx Therapeutics
• Bardoxolone methyl: Reata Pharmaceuticals

Autosomal Dominant Polycystic Kidney Disease Route of Administration
Autosomal Dominant Polycystic Kidney Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
• Inhalation
• Inhalation/Intravenous/Oral
• Intranasal
• Intravenous
• Intravenous/ Subcutaneous
• NA
• Oral
• Oral/intranasal/subcutaneous
• Parenteral
• Subcutaneous

Autosomal Dominant Polycystic Kidney Disease Molecule Type
Autosomal Dominant Polycystic Kidney Disease Products have been categorized under various Molecule types, such as
• Antibody
• Antisense oligonucleotides
• Immunotherapy
• Monoclonal antibody
• Peptides
• Protein
• Recombinant protein
• Small molecule
• Stem Cell
• Vaccine

Autosomal Dominant Polycystic Kidney Disease Pipeline Therapeutics Assessment
• Autosomal Dominant Polycystic Kidney Disease Assessment by Product Type
• Autosomal Dominant Polycystic Kidney Disease By Stage and Product Type
• Autosomal Dominant Polycystic Kidney Disease Assessment by Route of Administration
• Autosomal Dominant Polycystic Kidney Disease By Stage and Route of Administration
• Autosomal Dominant Polycystic Kidney Disease Assessment by Molecule Type
• Autosomal Dominant Polycystic Kidney Disease by Stage and Molecule Type

DelveInsight's Autosomal Dominant Polycystic Kidney Disease Report covers around 12+ products under different phases of clinical development like-
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Autosomal Dominant Polycystic Kidney Disease product details are provided in the report. Download the Autosomal Dominant Polycystic Kidney Disease pipeline report to learn more about the emerging Autosomal Dominant Polycystic Kidney Disease therapies - https://www.delveinsight.com/report-store/autosomal-dominant-polycystic-kidney-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Some of the key companies in the Autosomal Dominant Polycystic Kidney Disease Therapeutics Market include:
Key companies developing therapies for Autosomal Dominant Polycystic Kidney Disease are - Galapagos NV, Reata Pharmaceuticals, Kadmon Pharmaceuticals, Sanofi, Anakuria Therapeutics, Regulus Therapeutics, AceLink Therapeutics, Healx, XORTX Therapeutics, Poxel, Alebund Pharmaceuticals, Chinook Therapeutics, and others.

Autosomal Dominant Polycystic Kidney Disease Pipeline Analysis:
The Autosomal Dominant Polycystic Kidney Disease pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Autosomal Dominant Polycystic Kidney Disease with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Autosomal Dominant Polycystic Kidney Disease Treatment.
• Autosomal Dominant Polycystic Kidney Disease key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Autosomal Dominant Polycystic Kidney Disease Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Autosomal Dominant Polycystic Kidney Disease market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Autosomal Dominant Polycystic Kidney Disease drugs and therapies - https://www.delveinsight.com/sample-request/autosomal-dominant-polycystic-kidney-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Autosomal Dominant Polycystic Kidney Disease Pipeline Market Drivers
Increase in the prevalence of Autosomal Dominant Polycystic Kidney Disease, increase in the number of research and development activities are some of the important factors that are fueling the Autosomal Dominant Polycystic Kidney Disease Market.

Autosomal Dominant Polycystic Kidney Disease Pipeline Market Barriers
However, side-effects associated with the treatment of Autosomal Dominant Polycystic Kidney Disease, high cost associated with the treatment and other factors are creating obstacles in the Autosomal Dominant Polycystic Kidney Disease Market growth.

Scope of Autosomal Dominant Polycystic Kidney Disease Pipeline Drug Insight
• Coverage: Global
• Key Autosomal Dominant Polycystic Kidney Disease Companies: DiNAQOR AG, Poxel, AceLink Therapeutics, Regulus Therapeutics, Reata Pharmaceuticals, Sanofi, Galapagos NV, Janssen Pharmaceuticals, Xortx Therapeutics, and others
• Key Autosomal Dominant Polycystic Kidney Disease Therapies: DINAK 001, PXL770, AL01211, RGLS8429, Bardoxolone methyl, Tesevatinib/KD019, GLPG2737, AT-20494, XRx-008, and others
• Autosomal Dominant Polycystic Kidney Disease Therapeutic Assessment: Autosomal Dominant Polycystic Kidney Disease current marketed and Autosomal Dominant Polycystic Kidney Disease emerging therapies
• Autosomal Dominant Polycystic Kidney Disease Market Dynamics: Autosomal Dominant Polycystic Kidney Disease market drivers and Autosomal Dominant Polycystic Kidney Disease market barriers

Request for Sample PDF Report for Autosomal Dominant Polycystic Kidney Disease Pipeline Assessment and clinical trials - https://www.delveinsight.com/sample-request/autosomal-dominant-polycystic-kidney-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Table of Contents
1. Autosomal Dominant Polycystic Kidney Disease Report Introduction
2. Autosomal Dominant Polycystic Kidney Disease Executive Summary
3. Autosomal Dominant Polycystic Kidney Disease Overview
4. Autosomal Dominant Polycystic Kidney Disease- Analytical Perspective In-depth Commercial Assessment
5. Autosomal Dominant Polycystic Kidney Disease Pipeline Therapeutics
6. Autosomal Dominant Polycystic Kidney Disease Late Stage Products (Phase II/III)
7. Autosomal Dominant Polycystic Kidney Disease Mid Stage Products (Phase II)
8. Autosomal Dominant Polycystic Kidney Disease Early Stage Products (Phase I)
9. Autosomal Dominant Polycystic Kidney Disease Preclinical Stage Products
10. Autosomal Dominant Polycystic Kidney Disease Therapeutics Assessment
11. Autosomal Dominant Polycystic Kidney Disease Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Autosomal Dominant Polycystic Kidney Disease Key Companies
14. Autosomal Dominant Polycystic Kidney Disease Key Products
15. Autosomal Dominant Polycystic Kidney Disease Unmet Needs
16 . Autosomal Dominant Polycystic Kidney Disease Market Drivers and Barriers
17. Autosomal Dominant Polycystic Kidney Disease Future Perspectives and Conclusion
18. Autosomal Dominant Polycystic Kidney Disease Analyst Views
19. Appendix
20. About DelveInsight

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