NSCLC Treatment Market Size, Drugs, Emerging Therapies and Companies 2032 | DelveInsight

DelveInsight's "NSCLC Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the NSCLC, historical and forecasted epidemiology as well as the NSCLC market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

Explore the intricate details of the NSCLC Market: Uncover drug uptake, treatment dynamics, and epidemiological trends with our comprehensive NSCLC Market Forecast. Click here to stay ahead in healthcare innovation @ NSCLC Market Size- https://www.delveinsight.com/sample-request/non-small-cell-lung-carcinoma-nsclc-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the NSCLC Market Report
• In October 2024:- Alliance Foundation Trials LLC- This randomized phase II design provides a fairly rapid way to determine which of two potential neoadjuvant immunotherapy regimens holds the most promise for evaluation in a subsequent phase III trial against standard of care adjuvant immunotherapy. The AFT-16 trial of neoadjuvant atezolizumab in this setting provided proof of concept for safety of the neoadjuvant approach and for outcomes that compare favorably with standard of care therapy.
• In October 2024: Amgen- A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of AMG 193 in Subjects With Methylthioadenosine Phosphorylase (MTAP)-Deleted Previously Treated Advanced Non-Small Cell Lung Cancer (NSCLC). The main objective of the study is to characterize safety and efficacy of 2 dose levels of AMG 193 by investigator, and to evaluate AMG 193 monotherapy efficacy by Blinded Independent Central Review (BICR).
• In October 2024: Pfizer- The purpose of this continuation study is to provide continued access to crizotinib treatment for eligible participants from a current Pfizer sponsored crizotinib clinical study that is planned to close. Participants not previously enrolled or who have discontinued study treatment or safety follow-up in a current Pfizer sponsored crizotinib clinical study are not eligible for participation in this continuation study.
• According to DelveInsight's data, about 7 out of 10 patients in the United States had metastatic NSCLC stage IIIb and IV.
• According to the research study of Serizawa et al. (2014), the stage-specific diagnosed cases were observed to be approximately 25%, 7%, 21%, and 46% for Stage I, Stage II, Stage III, And Stage IV cases of NSCLC.
• The leading NSCLC Companies such as Convalife, Tiziana Life Science Ltd, Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd., Bristol-Myers Squibb, Akeso, RemeGen, and others.
• Promising NSCLC Therapies such as TEPMETKO (tepotinib), Romiplostim, AMG 510, and others.

Delve deep into the NSCLC Market Landscape: Analyze drug adoption, treatment paradigms, and epidemiological shifts in our detailed NSCLC Market Forecast. Click here to shape the future @ NSCLC Epidemiology Insights- https://www.delveinsight.com/sample-request/non-small-cell-lung-carcinoma-nsclc-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

NSCLC Overview
NSCLC stands for Non-Small Cell Lung Cancer. It is the most common type of lung cancer, accounting for about 85% of all lung cancer cases. NSCLC is a group of lung cancers that behave in a similar way and can be treated similarly.

NSCLC Epidemiology Insights
• Total Incident cases of NSCLC patients
• Total Diagnosed cases of NSCLC patients by Stages
• Total NSCLC cases of patients by Genetic mutation/Biomarkers
• Total Treated cases of NSCLC patients by Line of Therapies
• Total Incident cases of NSCLC patients by Histology

Navigate the complexities of the NSCLC Market: Gain insights into drug trends, treatment scenarios, and epidemiological data through our insightful NSCLC Market Forecast. Click here to get more insights @ NSCLC Treatment Market- https://www.delveinsight.com/sample-request/non-small-cell-lung-carcinoma-nsclc-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

NSCLC Treatment Landscape
There are different types of treatment available for NSCLC; however, mainly 10 types of standard treatment are used, which include Surgery, Radiation therapy, Chemotherapy, Targeted therapy, Immunotherapy, Laser therapy, Photodynamic therapy (PDT), Cryosurgery, Electrocautery, and Watchful waiting. To recommend a treatment option to a patient of NSCLC, several key factors are taken into consideration, such age of the patient, previous medical history, health status, and smoking history. Along with those, another essential factor to consider is the stage of cancer at the time of diagnosis. Staging is usually carried out twice: after clinical and radiological examinations; and after surgery, in the case of the surgically resected tumor. Furthermore, biological testing of the tumor is also crucial to understand the presence of specific mutations.
The main choice of treatment for cancer, before the discovery of targeted therapies, was chemotherapy. Chemotherapy works by disrupting the way that cancer cells grow and divide. However, these drugs can also affect normal cells. Chemotherapy can be given before or after surgery for NSCLC. Some people have chemotherapy at the same time as radiotherapy-this is called chemoradiotherapy. Chemotherapy may be given to try to cure cancer or to prolong life and control symptoms (palliative care).

NSCLC Market Dynamics
The NSCLC Market Dynamics is anticipated to change in the coming years owing to the improvement in the rise in number of healthcare spending across the world. Key players, such as AstraZeneca, Bristol-Myers-Squibb, AbbVie, Roche, Merck , Novartis, Pfizer, Takeda Pharmaceuticals, Eli lilly, Johnson & Johnson, Sanofi, GlaxoSmithKline, and others. are involved in developing drugs for NSCLC.

Unlock insights into the NSCLC Market: discover drug uptake patterns, treatment landscapes, and epidemiological insights with our exclusive NSCLC Market Forecast. Click here @ NSCLC Market Drivers and Barriers- https://www.delveinsight.com/sample-request/non-small-cell-lung-carcinoma-nsclc-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

NSCLC Therapies and Companies
1. Nazartinib/EGF816: Novartis Pharmaceuticals
2. Capmatinib/INC280: Novartis Pharmaceuticals
3. Telisotuzumab Vedotin: AbbVie
4. JNJ-61186372/JNJ-6372: Janssen Pharmaceuticals
5. Ensartinib/X-396: Xcovery
6. Selpercatinib (LY3527723/LOXO-292): Eli Lilly and Company
7. SAR408701: Sanofi
8. Braftovi/encorafinib + Mektovi/binimetinib: Pfizer
9. PADCEV (enfortumab vedotin/ASG-22ME): Astellas Pharma/Seattle Genetics
10. TAK-788: Takeda Pharmaceuticals
11. Canakinumab/(ACZ885): Novartis
12. BAVENCIO (Avelumab): Merck/Pfizer
13. Veliparib: AbbVie
14. Sitravatinib (MGCD516): Mirati Therapeutics/Bristol-Myers Squibb/Beigene
15. M7824: Merck/GlaxoSmithKline
16. AMG 510: Amgen
17. INCMGA00012 (MGA012): Incyte Corporation
18. Romiplostim: Amgen
19. TEPMETKO (tepotinib): Merck

NSCLC Drugs Uptake
• Telisotuzumab Vedotin by AbbVie is an antibody drug conjugate (ADC) targeting c-Met that is being investigated to treat NSCLC. Upon intravenous administration, the monoclonal antibody moiety of Telisotuzumab Vedotin targets and binds to c-Met expressed on tumor cells. Upon binding, internalization and enzymatic cleavage, the cytotoxic agent MMAE is released into the cytosol. MMAE binds to tubulin and inhibits tubulin polymerization, which results in G2/M phase arrest and tumor cell apoptosis. This kills the c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis and tumor angiogenesis. It demonstrated a promising ORR along with a tolerable safety profile in a phase II trial.
• Ensartinib/X-396 (Xcovery) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Through oral administration, ensartinib binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. ALK is not expressed in healthy adult human tissue but ALK dysregulation and gene rearrangements are associated with a series of tumors; ALK mutations are associated with acquired resistance to small molecule tyrosine kinase inhibitors. Besides ALK, ensartinib also potently inhibits TRKA fusions, TRKC, ROS1, EphA2, and c-MET.
• SAR408701 (Sanofi) is an immunoconjugate consisting of anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) conjugated to a cytotoxic agent, with potential antineoplastic activity. Upon administration of anti-CEACAM5 antibody-drug conjugate SAR408701, the antibody moiety targets CEACAM5 on tumor cells. Upon antibody/antigen binding and internalization, the immunoconjugate releases the cytotoxic agent, which results in tumor cell death. CEACAM5, a member of the CEA family of proteins that plays a key role in cell migration, cell invasion, and cell adhesion, is overexpressed by a variety of cancer cell types.

Gain a strategic edge in the NSCLC Market: explore comprehensive drug insights, treatment updates, and epidemiological forecasts in our in-depth NSCLC Market Forecast. Click here to lead in advancements @ NSCLC Clinical Trials Assessment- https://www.delveinsight.com/sample-request/non-small-cell-lung-carcinoma-nsclc-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the NSCLC Market Report
• Coverage- 7MM
• NSCLC Companies- Convalife, Tiziana Life Science Ltd, Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd., Bristol-Myers Squibb, Akeso, RemeGen, and others.
• NSCLC Therapies- TEPMETKO (tepotinib), Romiplostim, AMG 510, and others.
• NSCLC Market Dynamics: NSCLC Market drivers and NSCLC Market Barriers
• NSCLC Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• NSCLC Unmet Needs, KOL's views, Analyst's views, NSCLC Market Access and Reimbursement

Table of Content
1. Key Insights
2. Executive Summary of NSCLC
3. Competitive Intelligence Analysis for NSCLC
4. NSCLC: Market Overview at a Glance
5. NSCLC: Disease Background and Overview
6. Patient Journey
7. NSCLC Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. NSCLC Unmet Needs
10. Key Endpoints of NSCLC Treatment
11. NSCLC Marketed Products
12. NSCLC Emerging Therapies
13. NSCLC: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of NSCLC
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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