Press release
Rising Demand for Active Pharmaceutical Ingredients Driven by Increasing Drug Development and Chronic Illnesses
Active Pharmaceutical Ingredients Market
According to a report by the European Commission's Joint Research Centre, the cancer burden in Europe surged to 2.7 million new cases and 1.3 million deaths in 2020. Meanwhile, the World Health Organization (WHO) highlights that cardiovascular diseases (CVDs) claimed nearly 17.9 million lives globally, making up 32% of all deaths. These alarming statistics suggest that pharmaceutical and biotechnology companies have a growing opportunity to create new chemical compounds targeting severe health issues, particularly in areas like cancer and cardiovascular treatment.
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The increasing prevalence of chronic diseases is a key factor driving market growth. A study by the Indian Brand Equity Foundation (IBEF) revealed that the pharmaceutical industry in India accounts for over 50% of the global vaccine supply, 40% of generic medications in the U.S., and 25% of the UK medication market. The Indian Economic Survey projects the country's pharmaceutical market will expand from USD 42 billion in 2021 to USD 65 billion by 2024.
Furthermore, the complexity of chronic diseases and the rising number of cases demand innovative drug solutions, especially biologics. This trend has led to increased imports of pharmaceutical raw materials from emerging markets to support the production of advanced biopharmaceuticals. Additionally, pharmaceutical companies are intensifying their focus on R&D to introduce new drugs to the market, which is expected to further boost revenue growth.
Despite the promising outlook, the market faces challenges, including fluctuations in drug pricing regulations, especially in countries like China, which is a major supplier of active ingredients. In August 2018, for example, a price surge for chlorpheniramine API occurred due to market manipulation by local suppliers. This situation underscores the need for stable pricing strategies and oversight in the industry.
Recent developments indicate a trend of biopharmaceutical companies partnering with Contract Development and Manufacturing Organizations (CDMOs) to enhance their manufacturing capabilities. For instance, AGC Biologics announced a collaboration with Ono Pharmaceutical Co., Ltd. to produce innovative biopharmaceuticals in clinical development. This strategic partnership highlights the importance of technical expertise and production capacity in meeting the growing demand for APIs.
The global API market can be segmented into innovative and generic APIs. The innovative API segment holds the largest market share, driven by the need for advanced treatment options and technological advancements in healthcare. These APIs are often protected by patents, granting companies exclusivity to benefit from their R&D investments. Growing interest in precision medicine, tailored to individual patient needs, further supports this segment's growth.
The generic API segment is also expected to grow, albeit at a moderate pace, due to the expiration of patents for branded medications and the increasing popularity of over-the-counter (OTC) drugs, which offer more affordable alternatives.
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The market can also be categorized based on the synthesis type into synthetic and biotech APIs. The synthetic API segment is projected to dominate the market, thanks to the precise control over chemical synthesis processes that ensure product purity and scalability. This feature is especially crucial for widespread illnesses requiring large-scale drug production.
Meanwhile, the biotech API segment is anticipated to see steady growth, propelled by the rising demand for biopharmaceuticals and the increasing approval of biologics, including vaccines and recombinant proteins. For example, Richcore LifeSciences, an Indian biotechnology firm, has recently expanded its manufacturing capacity to support the production of recombinant proteins.
In terms of therapeutic applications, the cardiovascular disease segment is expected to generate the largest revenue share, driven by the increasing prevalence of heart-related conditions. Organizations like the World Heart Federation and government initiatives are working to raise awareness about these diseases, which will likely contribute to market growth. Additionally, the oncology segment is projected to experience the fastest growth due to the rising incidence of cancer and lifestyle changes leading to sedentary habits.
Overall, the Active Pharmaceutical Ingredients market is on a positive trajectory, bolstered by the need for innovative treatments and a proactive approach to addressing chronic health issues. As companies continue to invest in R&D and strategic partnerships, the market is set for robust growth in the coming years.
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API Top Companies and Competitive Landscape
The global Active Pharmaceutical Ingredients (API) market is fairly fragmented with many large and medium-sized players accounting for majority of market revenue. Major players are deploying various strategies, entering into mergers & acquisitions, strategic agreements & contracts, developing, testing, and introducing more effective Active Pharmaceutical Ingredients (API) in the market.
Some major players included in the global Active Pharmaceutical Ingredients (API) market report are:
AbbVie Inc.
Pfizer, Inc.
Sanofi
Boehringer Ingelheim
Bristol-Myers Squibb
Teva Pharmaceutical Industries Ltd.
ELI Lilly and Company
GlaxoSmithKline plc.
Merck & Co., Inc.
Lonza
Hisun USA, Inc.
Biocon Ltd,
BASF SE
Cambrex Corporation
Active Pharmaceutical Ingredients Latest Industry Updates
In May 2023, May SynCrest Inc., a peptide and nucleotide Contract Research, Development and Manufacturing Organization (CRDMO) jointly owned by Otsuka Chemical Co., Ltd. and Yokogawa Electric Corporation, announced that pharmaceutical companies and research institutions in Japan, Europe, North America, and South America can now avail its services. With its advanced continuous flow synthesis with in-line monitoring, the company is able to produce raw materials, intermediates, and APIs while addressing the specific issues at every point of the drug development value chain.
In March 2021, Rodeo Therapeutics, a biopharmaceutical company that specializes in creating small molecule treatments, was confirmed to have been acquired by Amgen. With the acquisition, Amgen will be able to increase the range of its inflammatory Active Pharmaceutical Ingredients (API).
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Active Pharmaceutical Ingredients Market Segmentation Analysis
For the purpose of this report, Emergen Research has segmented the global Active Pharmaceutical Ingredients (API) market on the basis of drug type, type of manufacturer, type of synthesis, therapeutic application, and region:
Type Outlook (Revenue, USD Billion; 2019-2032)
Innovative Active Pharmaceutical Ingredients (API)
Generic Active Pharmaceutical Ingredients (API)
Drug Type Outlook (Revenue, USD Billion; 2019-2032)
Prescription Drugs
Over-the-Counter (OTC) Drugs
Potency Outlook (Revenue, USD Billion; 2019-2032)
Traditional API
Highly Potent API (HPAPI)
Type of Manufacturer Outlook (Revenue, USD Billion; 2019-2032)
Captive Manufacturers
Merchant API Manufacturers
Type of Synthesis Outlook (Revenue, USD Billion; 2019-2032)
Synthetic Active Pharmaceutical Ingredients (API)
Synthesis API, by Type
Innovative Synthetic APIs
Generic Synthetic APIs
Biotech Active Pharmaceutical Ingredients (API)
Biotech API, by Type
Innovative Biotech APIs
Biosimilars
Biotech API, by Product
Monoclonal Antibodies
Vaccines
Cytokines
Fusion Proteins
Therapeutic Enzymes
Blood Factors
Biotech API, by Expression System
Mammalian Expression Systems
Microbial Expression Systems
Yeast Expression Systems
Transgenic Animal Systems
Others
Therapeutic Application Outlook (Revenue, USD Billion; 2019-2032)
Cardiovascular Diseases (CVDs)
Oncology
Central Nervous System (CNS) and Neurology
Orthopedic
Endocrinology
Pulmonology
Gastroenterology
Nephrology
Others
Regional Outlook (Revenue, USD Billion; 2019-2032)
North America
U.S.
Canada
Europe
Germany
France
UK
Italy
Spain
Benelux
Russia
Rest of Europe
Asia Pacific
China
Japan
South Korea
India
ASEAN Countries
Oceania
Rest of APAC
Latin America
Brazil
Mexico
Rest of LATAM
Middle East & Africa
GCC Countries
Israel
Turkey
South Africa
Rest of Middle East & Africa
Read More Related Report
Active Pharmaceutical Ingredients (API) Market Size @ https://www.emergenresearch.com/industry-report/active-pharmaceutical-ingredients-market/market-size
Active Pharmaceutical Ingredients (API) Market Share @ https://www.emergenresearch.com/industry-report/active-pharmaceutical-ingredients-market/market-share
Active Pharmaceutical Ingredients (API) Market Trends @ https://www.emergenresearch.com/industry-report/active-pharmaceutical-ingredients-market/market-trends
Active Pharmaceutical Ingredients (API) Regional Market Demand @ https://www.emergenresearch.com/industry-report/active-pharmaceutical-ingredients-market/regional-market-demand
Active Pharmaceutical Ingredients (API) Market Analysis @ https://www.emergenresearch.com/industry-report/active-pharmaceutical-ingredients-market/market-analysis
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Emergen Research is a market research and consulting company that provides syndicated research reports, customized research reports, and consulting services. Our solutions purely focus on your purpose to locate, target, and analyse consumer behavior shifts across demographics, across industries, and help clients make smarter business decisions. We offer market intelligence studies ensuring relevant and fact-based research across multiple industries, including Healthcare, Touch Points, Chemicals, Types, and Energy. We consistently update our research offerings to ensure our clients are aware of the latest trends existent in the market. Emergen Research has a strong base of experienced analysts from varied areas of expertise. Our industry experience and ability to develop a concrete solution to any research problems provides our clients with the ability to secure an edge over their respective competitors.
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