Optical Genome Mapping Market Size, Share, Growth and Trends, Report 2024-2031

Optical Genome Mapping (OGM) is an advanced imaging technology that detects structural variations in DNA with high precision. It works by evaluating the fluorescent labeling pattern of individual DNA molecules, offering an unbiased, genome-wide assessment of structural variants as small as 500 base pairs (bp). This resolution far surpasses that of traditional cytogenetic techniques.

OGM employs a specialized DNA extraction protocol designed to isolate ultra-high molecular weight (UHMW) DNA. Unlike standard column-based methods, which can fragment DNA, OGM's paramagnetic disk system traps the DNA during washing steps, minimizing shearing forces. This process results in DNA fragments ranging from 150 kilobases (kb) to megabases (Mbp) in size, approximately 5-10 times longer than those obtained from conventional extraction methods. This larger fragment size allows for more comprehensive and accurate genomic analysis.

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Key Developments:

• In August 2023, Bionano Genomics, Inc. participated in the Cancer Genomics Consortium (CGC) 2023 Annual Meeting, where it showcased the utility of optical genome mapping (OGM) for research on solid tumors and hematological malignancies. The event included scientific platform and poster presentations, along with a panel discussion featuring prominent researchers in the cancer genomics field.

• In July 2023, India's Centre for Cellular and Molecular Biology (CCMB) introduced a cutting-edge genetic testing technique, Optical Genome Mapping (OGM). This advanced method allows for the precise detection of genomic abnormalities responsible for various genetic disorders.

• In March 2023, Bionano Genomics launched two clinical tests based on OGM technology: the OGM-Dx prenatal whole genome structural variant test and the OGM-Dx postnatal whole genome structural variant test. These tests provide comprehensive genetic analysis to identify structural variations that may contribute to developmental or genetic conditions.

Market Dynamics:

Increasing advancements in optical mapping technologies

Continuous advances in optical mapping technology have played a pivotal role in driving market expansion. Innovations in high-resolution imaging, DNA labeling, and data processing algorithms have enhanced the accuracy and efficiency of optical genome mapping (OGM), making it a practical choice for applications such as genome assembly, structural variation identification, and genotyping.

For example, in January 2023, Bionano Genomics launched several new products and improvements to its OGM workflow. These included enhanced sample preparation kits, faster turnaround times for DNA labeling and imaging, and increased throughput and quality metrics. The new sample prep kits, chips, and software updates were designed based on customer feedback, enabling better performance in routine genome analysis.

Additionally, the global optical genome mapping market is driven by factors such as increased government funding, research initiatives, and ongoing advancements in genomic research, all contributing to the market's growth over the forecast period.

Segment Covered in Optical Genome Mapping Market:

By Product Type: Consumables, Instruments, Software.

By Application: Structural Variant Detection, Genome Assembly, Microbial Strain Typing, Others.

By End User: Biotechnology and Pharmaceutical Companies, Clinical Laboratories, Academic research institutes, Others.

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Key players involved in Optical Genome Mapping Market:

• Bionano Genomics
• Nucleome Informatics Private Limited
• Praxis Genomics, LLC
• MedGenome
• INRAE (French Plant Genomic Resources Center (CNRGV))
• PerkinElmer (PerkinElmer Genomics)
• Genohub Inc.
• Hofkens Lab
• Cerba
• Nabsys

*Note:
• Additionally, I wanted to highlight that the full version of the report includes an in-depth analysis of emerging players and startups, which will provide valuable insights into the evolving market landscape and key strategies being adopted.

Regional Analysis:

The Optical Genome Mapping Market report focuses on six major regions: North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa. The report offers detailed insight into new product launches, new technology evolutions, innovative services, and ongoing R&D. The report discusses a qualitative and quantitative market analysis, including PEST analysis, SWOT analysis, and Porter's five force analysis. The Optical Genome Mapping Market report also provides fundamental details such as raw material sources, distribution networks, methodologies, production capacities, industry supply chain, and product specifications.

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