Chronic Lymphocytic Leukemia Therapeutics Market 2016: Global Industry Insights,Market shares and Forecasts to 2021

Chronic Lymphocytic Leukemia (CLL) is a type of hematological malignancy marked by excessive proliferation of abnormal white blood cells. Chronic Lymphocytic Leukemia (CLL) predominantly affects the B-cell lymphocytes which are involved in the production of antibodies to fight against infections and foreign antigens. Rising incidence of CLL coupled with a high rate of mortality, demonstrates the unmet market need for better therapeutics. According to the American Cancer Society (ACS) estimate, more than 14000 new cases and more than 4,500 deaths are expected in the year 2015.

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CLL is more common among the aging population, with a higher frequency in the people aged 70 or above.Family history of blood disorders and excessive exposure to harmful chemicals are the two important drivers for CLL treatment market. Higher incidences of leukemia coupled with improved diagnosis for CLL, growing disease awareness and rising incidences of comorbidities, especially among elders are other factors significant in determining the market growth. Furthermore, breakthrough therapy designation by FDA and discovery of some pipeline drugs would further accelerate the market growth. However, high cost of treatment, is likely to curtail the market growth.

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The global Chronic Lymphocytic Leukemia Therapeutics market is segmented on the basis of drug type, route of administration and geography. On the basis of drug type, the market is segmented into Chemotherapy, Targeted Therapies and Others. The Targeted Therapy market is further segmented into approved drugs and pipeline drugs. According to route of administration, the market is segmented into Oral drugs, Intravenous drugs and others. Geographically, the market is segmented across four regions namely North America, Europe, Asia Pacific and LAMEA.

Co-development and collaboration agreements are some of the key strategies adopted by leading market players. For instance, GlaxoSmithKline plc and Genmab A/S, have entered into co-development and collaboration agreement for drug Arzerra (ofatumumab), used in the treatment of relapsed CLL. Arzerra is a monoclonal antibody which targets CD20 molecule on the surface of CLL cells. Recently, Venetoclax, an investigational drug for the treatment of relapse or refractory CLL, has been granted Breakthrough Therapy Designation by US FDA. The drug is being developed by AbbVie in collaboration with Genentech and Roche.

The companies profiled in the report include, GlaxoSmithKline Plc, Biogen Idec, Genentech Inc., F. Hoffmann-La Roche AG, Genzyme Corporation, Teva Pharmaceutical Industries Ltd., Celgene Corporation, Genmab A/S and AstraZeneca plc.

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