Systemic Lupus Erythematosus Drug Market Report 2034: Epidemiology, Latest FDA Approvals | GlaxoSmithKline, AstraZeneca, Eli Lilly and Company, Biogen, UCB Pharma/Biogen, Immupharma

DelveInsight's "Systemic Lupus Erythematosus Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of the Systemic Lupus Erythematosus, historical and forecasted epidemiology as well as the Systemic Lupus Erythematosus market trends in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom) and Japan.

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Key Takeaways from the Systemic Lupus Erythematosus Market Research Report
• June 2024:- GlaxoSmithKline-A Phase 4, Multicenter, Prospective, Open-Label Study Describing the Efficacy and Safety of Belimumab Administered Subcutaneously in Adult Participants With Early Systemic Lupus Erythematosus.
• June 2024:- Novartis Pharmaceuticals- The purpose of this study is to evaluate long-term safety and tolerability of ianalumab in participants with systemic lupus erythematosus who have previously completed the treatment period in one of the two SIRIUS-SLE core studies (CVAY736F12301 or CVAY736F12302).
• June 2024:- Merck Sharp & Dohme LLC- The purpose of this study is to evaluate the efficacy and safety of MK-6194 in adult participants with Systemic Lupus Erythematosus. The primary hypothesis is that at least 1 of the MK-6194 arms is superior to placebo in the primary endpoint of percentage of participants with systemic lupus erythematosus responder index (SRI-4) response at Week 28.
• June 2024:- AbbVie- Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadacitinib is in treating adult participants with moderately to severely active SLE. Adverse events and change in the disease activity will be assessed.
• The increase in Systemic Lupus Erythematosus Market Size is a direct consequence of the increasing patient population and anticipated launch of emerging therapies in the 7MM.
• As per DelveInsight analysis, the Systemic Lupus Erythematosus Market is anticipated to witness growth at a considerable CAGR.
• As per analysis, the Systemic Lupus Erythematosus severity algorithm at baseline identified 12.8% patients with mild SLE.
• Among the 7MM, the United States accounted for the highest number of Systemic Lupus Erythematosus diagnosed prevalent cases. The total prevalent cases of SLE in the US were ~360,000 in 2023.
• The leading Systemic Lupus Erythematosus Companies working in the market include GlaxoSmithKline, AstraZeneca, Eli Lilly and Company, Biogen, UCB Pharma/Biogen, Immupharma, Hoffmann-La Roche, Xencor, Idorsia Pharmaceuticals, Bristol-Myers Squibb (Celgene), Resolve Therapeutics, Genentech (Roche), Pfizer, and others.
• Promising Systemic Lupus Erythematosus Pipeline Therapies in the various stages of development include LY3471851, Lupuzor, BIIB059, Dapirolizumab pegol, Gazyva, Cenerimod, and others.

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Systemic Lupus Erythematosus Overview
Systemic lupus erythematous, referred to as SLE is a chronic (long-term) disease that causes systemic inflammation which affects multiple organs. In addition to affecting the skin and joints, it can affect other organs in the body such as the kidneys, the tissue lining the lungs (pleura), heart (pericardium), and brain. Many patients experience fatigue, weight loss, and fever.

Systemic Lupus Erythematosus Epidemiology Segmentation in the 7MM
• Total Systemic Lupus Erythematosus Diagnosed Prevalent Cases
• Systemic Lupus Erythematosus Age-specific Diagnosed Prevalent Cases
• Systemic Lupus Erythematosus Severity-specific Diagnosed Prevalent Cases
• Systemic Lupus Erythematosus Gender-specific Diagnosed Prevalent Cases

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Systemic Lupus Erythematosus Treatment Market
Systemic Lupus Erythematosus treatment include NSAIDs and antimalarial agents, which are the first-line therapies formild SLE. In addition, glucocorticoids and cytotoxic or immunosuppressive agents-such as azathioprine, mycophenolatemofetil, cyclophosphamide, cyclosporine, and methotrexate -are used for SLE with organ involvement. The current market possesses two approved products, Benlysta (belimumab) and Saphnelo (anifrolumab-fnia).

Systemic Lupus Erythematosus Market Dynamics
The Systemic Lupus Erythematosus market dynamics is anticipated to change in the coming years owing to the improvement in the research and development activities for efficient treatment options to be available in the market. The launch of emerging therapies is expected during the forecast period of 2022-2032. Few major key players of the emerging therapy market of SLE includes ImmuPharma, Eli Lilly, BMS/Celgene, Idorsia, Biogen, Roche, etc.

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Systemic Lupus Erythematosus Emerging Therapy Assessment
Expected Launch of potential therapies may increase the market size in the coming years, assisted by an increase in the diagnosed prevalent population of SLE. Owing to the positive outcomes of the several products during the developmental stage by key players such as Immu Pharma, Eli Lilly, BMS/Celgene, Biogen, UCB Pharma, Roche, Idorsia, Resolve and others, the SLE market is expected to witness a significant positive shift in the forecast period of 2023-2032.

Systemic Lupus Erythematosus Drugs Uptake
• Lupuzor (also known as regiremod; IPP-201101), being developed by ImmuPharma, is a 21- mer linear peptide fragment analog. It has a novel mechanism of action aimed at modulating the body's immune system so that it does not attack healthy cells and avoids causing adverse side effects. The unique mechanism of action involves modulating the activation of auto-reactive T-cells. This targeted approach marks a paradigm shift in treating autoimmune diseases. ImmuPharma has completed the Phase III clinical trial for the treatment of SLE. Lupuzor demonstrated a superior response rate over placebo (61.5% vs 47.3%). ImmuPharma and US Avion Pharmaceuticals signed exclusive license and development agreement for Lupuzor to fund a new 'optimized' international Phase III trial which is expected to start by 2022. Avion Pharmaceuticals has the exclusive rights for the commercialization of Lupuzor in the US. ImmuPharma retains all the rights to commercialize Lupuzor outside of the US.
• Dapirolizumab pegol, developed by UCB Pharma and their partner Biogen. It is an investigational humanized anti-CD40L antibody fragment that acts by preventing the interaction between CD40L on T-cells with CD40 on antigen-presenting cells through interactions with its receptor-CD40. The drug failed to meet its primary endpoint in the Phase II trial. However, the company continued the development of dapirolizumab pegol. The product is currently being developed jointly by UCB and Biogen to treat SLE in a Phase III trial. The topline results are expected in H1 2024.

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Scope of the Systemic Lupus Erythematosus Market Research Report
• Coverage- 7MM
• Systemic Lupus Erythematosus Companies- GlaxoSmithKline, AstraZeneca, Eli Lilly and Company, Biogen, UCB Pharma/Biogen, Immupharma, Hoffmann-La Roche, Xencor, Idorsia Pharmaceuticals, Bristol-Myers Squibb (Celgene), Resolve Therapeutics, Genentech (Roche), Pfizer, and others.
• Systemic Lupus Erythematosus Pipeline Therapies- LY3471851, Lupuzor, BIIB059, Dapirolizumab pegol, Gazyva, Cenerimod, and others.
• Systemic Lupus Erythematosus Market Dynamics: Systemic Lupus Erythematosus Market Drivers and Barriers

Table of Content
1. Key Insights
2. Systemic Lupus Erythematosus Executive Summary
3. Systemic Lupus Erythematosus Competitive Intelligence Analysis
4. Systemic Lupus Erythematosus: Market Overview at a Glance
5. Systemic Lupus Erythematosus: Disease Background and Overview
6. Patient Journey
7. Systemic Lupus Erythematosus Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Systemic Lupus Erythematosus Unmet Needs
10. Key Endpoints of Systemic Lupus Erythematosus Treatment
11. Systemic Lupus Erythematosus Marketed Products
12. Systemic Lupus Erythematosus Emerging Therapies
13. Systemic Lupus Erythematosus: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Systemic Lupus Erythematosus Market Outlook
16. Access and Reimbursement Overview
17. KOL Views
18. Systemic Lupus Erythematosus Market Drivers
19. Systemic Lupus Erythematosus Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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