Press release
RAS-acting Agents Market Revenue to Cross $13.4 Billion by 2031 to Rise at a Stellar CAGR of 4.2% | Exclusive Research by Transparency Market Research
RAS-acting Agents market is estimated to attain a valuation of US$ 13.4 Bn by the end of 2031, states a study by Transparency Market Research (TMR). Besides, the report notes that the market is prognosticated to expand at a CAGR of 4.2% during the forecast period, 2023-2031
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The significant players operating in the global RAS-acting Agents market are
Novartis AG, Pfizer, Inc., AstraZeneca plc, Merck & Co., Inc., Sanofi S.A., Bristol-Myers Squibb Company, Daiichi Sankyo Company, Limited, Takeda Pharmaceutical Company Limited, Boehringer Ingelheim GmbH, and Johnson & Johnson
Market Dynamics
Clinical Indications: RAS-acting agents are indicated for the management of hypertension, heart failure, diabetic nephropathy, and chronic kidney disease, where RAS dysregulation contributes to volume overload, systemic vasoconstriction, and end-organ damage, necessitating targeted pharmacological interventions to mitigate cardiovascular and renal risk factors.
Guideline-Directed Therapy: RAS-acting agents are integral components of evidence-based guidelines for cardiovascular risk reduction and management of hypertension and heart failure, emphasizing their role in optimizing blood pressure control, preserving renal function, and reducing cardiovascular morbidity and mortality in high-risk patient populations.
Combination Therapy: RAS-acting agents are often used in combination with other antihypertensive medications, including diuretics, beta blockers, calcium channel blockers, and direct renin inhibitors, as well as lipid-lowering drugs and glucose-lowering agents, to achieve comprehensive cardiovascular risk reduction and optimize therapeutic outcomes in patients with complex comorbidities.
Therapeutic Indications
The RAS-Acting Agents Market encompasses a range of therapeutic indications, including:
Hypertension: RAS-acting agents are first-line agents for the management of hypertension, reducing blood pressure through vasodilation, natriuresis, and inhibition of aldosterone secretion, thereby lowering cardiovascular risk and preventing end-organ damage in hypertensive patients.
Heart Failure: RAS-acting agents are integral components of guideline-directed medical therapy for heart failure with reduced ejection fraction (HFrEF), reducing morbidity and mortality by blocking maladaptive neurohormonal activation, reversing cardiac remodeling, and improving left ventricular function and myocardial contractility.
Diabetic Nephropathy: RAS-acting agents are renoprotective in diabetic nephropathy, slowing the progression of renal disease, reducing proteinuria, and preserving glomerular filtration rate (GFR) by inhibiting intrarenal RAS activation, reducing glomerular pressure, and preventing glomerular sclerosis and interstitial fibrosis.
Recent Developments
Precision Medicine Approaches: Biomarker-guided therapy, genetic testing, and personalized treatment algorithms identify high-risk patients who may benefit from RAS-acting agents, allowing for individualized dosing, titration, and selection based on patient-specific factors, renal function, electrolyte status, and cardiovascular risk profile.
Novel Formulations: Extended-release formulations, fixed-dose combinations, and novel drug delivery systems enhance the pharmacokinetic profile, bioavailability, and therapeutic efficacy of RAS-acting agents, offering convenient dosing regimens and sustained clinical benefits in patients with cardiovascular and renal diseases.
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Market Segmentation -
Drug Class
ACE Inhibitors
Angiotensin II Receptor Blockers (ARBs)
Renin Inhibitors
Aldosterone Antagonists
Others (diuretics)
Indication
Hypertension
Heart Failure
Chronic Kidney Disease
Diabetic Nephropathy
Coronary Artery Disease
Distribution Channel
Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
This Report lets you identify the opportunities in RAS-acting Agents Market by means of a region:
North America (the United States, Canada, and Mexico)
Europe (Germany, UK, France, Italy, Russia, Turkey, etc.)
Asia-Pacific (China, Japan, Korea, India, Australia, and Southeast Asia (Indonesia, Thailand, Philippines, Malaysia, and Vietnam))
South America (Brazil etc.) The Middle East and Africa (North Africa and GCC Countries)
Key Features of the RAS-acting Agents Market Report: -
➤ Analyze competitive developments such as expansions, deployments, new product launches, and market acquisitions.
➤ Examine the market opportunities for stakeholders by identifying higher growth sections.
➤ To study and analyze the global RAS-acting Agents industry status and forecast including key regions.
➤ An in-depth analysis of key product segments and application spectrum, providing strategic recommendations to incumbents and new entrants to give them a competitive advantage over others.
➤ It provides a comprehensive analysis of key regions of the industry as well as a SWOT analysis and Porter's Five Forces analysis to provide a deeper understanding of the market.
➤ It helps you make strategic business decisions and investment plans.
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About Us Transparency Market Research
Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. The firm scrutinizes factors shaping the dynamics of demand in various markets. The insights and perspectives on the markets evaluate opportunities in various segments. The opportunities in the segments based on source, application, demographics, sales channel, and end-use are analysed, which will determine growth in the markets over the next decade.
Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers, made possible by experienced teams of Analysts, Researchers, and Consultants. The proprietary data sources and various tools & techniques we use always reflect the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in all of its business reports.
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