Merck KGaA (Germany) and Thermo Fisher Scientific, Inc. (US) are Leading Players in the Gene Editing Market

The gene editing market is projected to grow from USD 5.3 billion in 2023 to USD 10.6 billion by 2028 at a CAGR of 15.0%. Gene editing or genome engineering is the insertion, deletion, or replacement of DNA at a specific site in the genome of an organism or cell. It is usually achieved in the lab using genome-editing tools, such as CRISPR, TALEN, and ZFN. This emerging and rapidly evolving field enables the efficient and directed modification of cell lines and genomes of animals and plants.

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The reagents and consumables segment accounted for the largest share of the gene editing market in 2022

Based on product & service, the gene editing market is segmented into reagents & consumables, software & systems, and services. The reagents & consumables segment accounted for the largest share in 2022, particularly due to the frequent purchase of reagents in gene editing protocols coupled with high demand for genetic sequencing and editing. Reagents and consumables include various products, such as purification, library preparation, and target enrichment kits. Target enrichment kits allow researchers to target human or non-human DNA sequences of interest through custom-designed gene panels or focused exomes. A target enrichment kit consists of master-mix reagents and assays for isolating genomic regions of interest. These kits are used for editing exome sequences.

The CRISPR segment is expected to grow at the highest CAGR from 2023 to 2028

Based on technology, the gene editing market is segmented into CRISPR, TALEN, ZFN, antisense, and other technologies. The CRISPR segment accounted for the largest share of the gene editing market in 2022. Several factors such as ease of use, technical advantage over ZFN and TALEN, capability of generating large set of vectors to target numerous sites or genome-wide libraries have contributed to the dominance of the CRISPR segment in the market.

The pharmaceutical & biotechnology companies segment accounted for the largest share of the global gene editing market in 2022

The gene editing market is segmented into pharmaceutical & biotechnology companies, academic & research institutes, and other end users based on the end user. Pharmaceutical & biotechnology companies accounted for the largest share of the gene editing market in 2022. The large share of this segment can be attributed to the rise in the use of CRISPR technology, which is expected to increase the applications of gene therapies and provide remedies for genetic disorders, such as sickle-cell anemia.

North America dominates the global gene editing market throughout the forecast period

The gene editing market is segmented into five major regional segments, namely, North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. In 2022, North America accounted for the largest share in the gene editing market, which is attributed to the technological advancements, established research infrastructure, and demand for precision medicine.

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Key Market Players:

The prominent players in the global gene editing market include Merck KGaA (Germany), Thermo Fisher Scientific, Inc. (US), GenScript (China), Agilent Technologies (US), PerkinElmer (US), Lonza (Switzerland), Tecan Life Sciences (Switzerland), Sangamo Therapeutics (US), Editas Medicine (US), CRISPR Therapeutics AG (Switzerland), Precision Biosciences (US), Cellectis (France), Intellia Therapeutics (US), Bluebird Bio, Inc. (US), Regeneron Pharmaceuticals (US), AMSBIO (England), Creative Biogene (US), Synthego Corporation (US), and Beam Therapeutics Inc. (US).

Recent Developments:

In February 2023, GenScript (China) announced the expansion of its Singapore facility to provide a premium gene synthesis service. This marks a significant expansion of the company's advanced gene-synthesis capability and enables GenScript to provide the service levels required for novel vaccine and therapeutics development in life sciences.

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