Motor Neuron Disease Market to Expand at a Significant Growth Rate During the Forecast Period (2023-32) - DelveInsight | Cytokinetics, Biogen, Novartis, Amylyx, Ionis, Brainstorm Cell Therapeutics

As per DelveInsight, the Motor Neuron Disease Market is anticipated to evolve immensely in the coming years owing to the rise in the patient population in the 7MM and the launch of new therapies in the market.

DelveInsight's "Motor Neuron Disease Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Motor Neuron Disease Market Size and Share in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).

The market report covers emerging drugs, treatment practices, market share of individual Motor Neuron Disease therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Motor Neuron Disease treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of opportunities and assess the underlying potential of the market.

Motor Neuron Disease: An Overview
Motor neuron diseases (MNDs) is an umbrella term used for a group of diseases that result in progressive destruction of neurons and gradual deterioration of voluntary muscle function, leading to high mortality and morbidity.

Motor neuron diseases occur as the result of dysfunction of upper motor neurons in the precentral gyrus of the frontal lobe and/or lower motor neurons in the ventral horn of the spinal cord. In general, they cause weakness without notable sensory symptoms or pain. The most common motor neuron disease is amyotrophic lateral sclerosis. Other motor neuron diseases include hereditary spastic paraparesis, spinobulbar muscular atrophy, and infectious motor neuron diseases.

The symptoms of motor neurone disease begin gradually over weeks and months, usually on one side of the body initially, and get progressively worse. Common early symptoms include a weakened grip, which can cause difficulty picking up or holding objects, weakness at the shoulder that makes lifting the arm difficult, a "foot drop" caused by weak ankle muscles, dragging of the leg, and slurred speech.

Since the treatment of various motor neuron diseases and their mimics have markedly different treatments, accurate diagnosis is important. Motor neurone disease is usually diagnosed by a neurologist based on the symptoms and a physical examination. There's no single test for motor neurone disease, but the diagnosis is often obvious from a person's symptoms and physical examination by a neurologist.

Motor Neuron Disease Market Key Facts
• A study by Yedavalli V.S. et al., (2018), stated the average incidence of MNDs is 1-3 cases per 100,000. The prevalence of MND ranges from 1 to 9 cases per 100,000 worldwide. Of this group, amyotrophic lateral sclerosis (ALS) is by far the most common, comprising roughly 80%-90% of MND cases.
• According to a study by Kab S. et al., (2017), in France, MND incidence was 2.72/ 100,000 person-years. Incidence was higher in males than females. Incidence increased to a peak between 75 and 79 years of age and decreased thereafter.
• According to a study by Doi Y. et al., (2014), the annual crude prevalence and incidence rates of ALS per 100,000 people per year were 9.9 and 2.2 respectively. The highest prevalence as well as incidence was evident in the 70- to 79-years age group, and the male-female ratio was approximately 1.5.
• According to the NHS, motor neuron disease affects around two in every 100,000 people in the UK each year. There are about 5,000 people living with the condition in the UK at any one time.

Get a Detailed Overview of the Evolving Motor Neuron Disease Market Trends @
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Motor Neuron Disease Market
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Motor Neuron Disease therapies in the market. It also provides a detailed assessment of the Motor Neuron Disease market drivers & barriers, unmet needs, and emerging technologies.

The report gives complete details of the market trend for each marketed Motor Neuron Disease drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MOA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

Discover How the Motor Neuron Disease Market Will Grow by 2032 @
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Motor Neuron Disease Epidemiology
The epidemiology section covers detailed insights into the historical, and current Motor Neuron Disease patient pool and forecasted epidemiology trends for every seven major countries (7MM) from 2019 to 2032.

The Report Covers the Motor Neuron Disease Epidemiology Segmented as -
• Prevalent Population of Motor Neuron Disease in the 7MM (2019-2032)
• Type-specific Prevalent Population of Motor Neuron Disease in the 7MM (2019-2032)
• Age-specific Prevalent Cases of Motor Neuron Disease in the 7MM (2019-2032)
• Diagnosed and Treatable Population of Motor Neuron Disease in the 7MM (2019-2032)

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Motor Neuron Disease Drugs Uptake and Pipeline Development Activities
The drugs' uptake section focuses on the rate of uptake of the potential drugs recently launched in the Motor Neuron Disease market or expected to be launched during the study period. The analysis covers the market share by Motor Neuron Disease drugs, patient uptake by therapies, and sales of each drug.

The report's drugs uptake section helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs. It allows the comparison of the drugs based on market share and size, which again will be helpful in investigating factors important in understanding the market dynamics and in making financial and regulatory decisions.

The report also covers the Motor Neuron Disease Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Explore More About Ongoing Pipeline Development Activities in the Motor Neuron Disease Market @
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Motor Neuron Disease Therapeutics Assessment
Till date, there is no curative therapy for treatment of MND. Neuroprotection and symptomatic treatments remain the cornerstone of management for MND patients, typically undertaken in a multidisciplinary setting.

Complete understanding of the pathogenesis of Motor Neuron Disease, awaits successful and curative therapeutic responses from targeted therapies with fewer side effects. The pipeline for MND is robust, with many key players working towards therapy development targeting spinal muscular atrophy and amyotrophic lateral sclerosis.

Leading Companies in the Motor Neuron Disease Therapeutics Market Include
• Amylyx Pharmaceuticals
• Biogen
• Brainstorm Cell Therapeutics
• Cytokinetics
• Ionis Pharma
• Novartis
And Many Others

Emerging and Marketed Motor Neuron Disease Therapies Covered in the Report Include
• Reldesemtiv: Cytokinetics
• Tofersen: Biogen
• OAV-101: Novartis
• AMX0035: Amylyx Pharmaceuticals
• ION363: Ionis Pharma
• NurOwn: Brainstorm Cell Therapeutics
And Many More

Learn More About the Emerging Therapies and key Companies in the Motor Neuron Disease Therapeutics Market @
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Motor Neuron Disease Competitive Intelligence Analysis
4. Motor Neuron Disease Market Overview at a Glance
5. Motor Neuron Disease Background and Overview
6. Motor Neuron Disease Patient Journey
7. Motor Neuron Disease Epidemiology and Patient Population
8. Motor Neuron Disease Treatment Algorithm, Current Treatment, and Medical Practices
9. Motor Neuron Disease Unmet Needs
10. Key Endpoints of Motor Neuron Disease Treatment
11. Motor Neuron Disease Marketed Products
12. Motor Neuron Disease Emerging Therapies
13. Motor Neuron Disease Seven Major Market Analysis
14. Attribute Analysis
15. Motor Neuron Disease Market Outlook (7 major markets)
16. Motor Neuron Disease Access and Reimbursement Overview
17. KOL Views on the Motor Neuron Disease Market.
18. Motor Neuron Disease Market Drivers
19. Motor Neuron Disease Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.

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