Osteosarcoma Market Forecasts by DelveInsight Signal Groundbreaking Growth by 2032 | AlaMab, Zentalis, Merck Eprova, Eisai, Y-mAbs, AstraZeneca, Advenchen, Innovent, PersonGen, Cellectar, Hutchison, MacroGenics, Gradalis, Celgene, Oncternal

As per DelveInsight, the Osteosarcoma Market is anticipated to evolve immensely in the coming years owing to the rise in the number of cases of Osteosarcoma and the launch of new therapies in the market. Several major pharma companies are developing therapies for the treatment of patients with Osteosarcoma, some of which include Eisai (Lenvatinib), Bayer (BAY80-6946), MedPacto (Vactosertib), Zentalis Pharmaceuticals (Azenosertib), and Hutchmed (Surufatinib).

DelveInsight's "Osteosarcoma Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Osteosarcoma Market Size and Share in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).

The market report covers emerging drugs, treatment practices, market share of individual Osteosarcoma therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Osteosarcoma treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of opportunities and assess the underlying potential of the market.

Osteosarcoma: An Overview
Osteosarcoma (osteogenic sarcoma) is the most common type of bone cancer that usually develops in the osteoblast cells of the bone. It mostly occurs in the long bones around the knee. Other sites include the upper leg, or thighbone, the lower leg, upper arm bone, or any bone in the body, including those in the pelvis, shoulder, and skull. It may spread to nearby tissues, such as tendons or muscles, and may also metastasize through the bloodstream to other organs or bones in the body.

It can be classified as primary or secondary based on the location and spread of cancer. When cancer starts in bone tissue, it is called primary bone cancer. Whereas, when cancer cells travel to the bone from elsewhere, it is called secondary or metastatic bone cancer. Furthermore, based on the histological features, it can be categorized into high-grade, intermediate-grade, and low-grade osteosarcoma; each category has different subtypes.

Osteosarcoma can affect people of all ages, but it most often occurs in children and teens. The average age of diagnosis is 15 years. Before adolescence, it occurs equally in males and females, while after adolescence, it occurs slightly more often in males, possibly because of a longer period of skeletal growth.

The causes of osteosarcoma are unknown, but risk factors include radiation, rapid bone growth, inherited disorders, and the presence of certain benign (noncancerous) bone diseases.

Osteosarcoma Market Key Facts
• According to ESMO (2018), the occurrence rate of osteosarcoma is around 0.3 cases per 100,000 individuals per year. However, the incidence is more prevalent among adolescents, specifically ranging from 0.8 to 1.1 cases per 100,000 individuals per year within the age group of 15 to 19 years.
• According to the American Cancer Society, most osteosarcomas occur in children, teens, and young adults between the ages of 10 and 30. Teens are the most commonly affected age group, but people of any age can develop osteosarcoma. About 1 in 10 osteosarcomas occur in people older than 60.
• As per DelveInsight analysts, the total incident population of osteosarcoma in the 7MM was ~2,200 in 2022.
• Among EU4 and the UK, Germany had the highest incident population, followed by France and the UK.
• In 2022, Japan had ~190 cases of osteosarcoma, out of which males and females contributed to ~100 and ~90 cases, respectively.
• The estimates show the highest incidence of cases of osteosarcoma in the United States, with ~1,100 cases in 2022.
• Age groups 0-24 years contributed to ~55% of the total incident cases of osteosarcoma in Japan, in 2022.

Get a Detailed Overview of the Evolving Osteosarcoma Market Trends @
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Osteosarcoma Market
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Osteosarcoma therapies in the market. It also provides a detailed assessment of the Osteosarcoma market drivers & barriers, unmet needs, and emerging technologies.

The report gives complete details of the market trend for each marketed Osteosarcoma drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MOA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

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Osteosarcoma Epidemiology
The epidemiology section covers detailed insights into the historical, and current Osteosarcoma patient pool and forecasted epidemiology trends for every seven major countries (7MM) from 2019 to 2032.

The Report Covers the Osteosarcoma Epidemiology Segmented as -
• Total Incident Cases of Osteosarcoma in the 7MM [2019-2032]
• Gender-specific Incident Cases of Osteosarcoma in the 7MM [2019-2032]
• Stage-specific Incident Cases of Osteosarcoma in the 7MM [2019-2032]
• Age-specific Incident Cases of Osteosarcoma in the 7MM [2019-2032]
• Subtypes specific Incident Cases of Osteosarcoma in the 7MM [2019-2032]
• Site-specific Incident Cases of Osteosarcoma in the 7MM [2019-2032]

Get Key Insights Into the Evolving Osteosarcoma Epidemiology Trends @
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Osteosarcoma Drugs Uptake and Pipeline Development Activities
The drugs' uptake section focuses on the rate of uptake of the potential drugs recently launched in the Osteosarcoma market or expected to be launched during the study period. The analysis covers the market share by Osteosarcoma drugs, patient uptake by therapies, and sales of each drug.

The report's drugs uptake section helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs. It allows the comparison of the drugs based on market share and size, which again will be helpful in investigating factors important in understanding the market dynamics and in making financial and regulatory decisions.

The report also covers the Osteosarcoma Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Explore More About Ongoing Pipeline Development Activities in the Osteosarcoma Market @
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Osteosarcoma Therapeutics Assessment
In general, the commonly available modalities for the treatment of osteosarcoma include chemotherapy, surgery, and radiation therapy. Although some novel insights have been offered for clinical and scientific relevance, minor progress has been made in osteosarcoma treatment following a significant survival improvement in the late 1980s with the addition of chemotherapy to surgery.

The mainstream chemotherapeutic agents for treatment include methotrexate, doxorubicin, cisplatin, and ifosfamide approved by the NCCN Guidelines. Since the introduction of chemotherapy, single-agent treatment of osteosarcoma has been considered inadequate, the majority of osteosarcoma treatment is based on a combination of two or more of only four drugs: doxorubicin, cisplatin, methotrexate, and ifosfamide. Therefore, treatment options available for first-line osteosarcoma patients consist of combinations including doxorubicin + cisplatin (DC), methotrexate + doxorubicin + cisplatin (MDC), and methotrexate + doxorubicin + cisplatin + ifosfamide (MDCI). The function of second-line chemotherapy for recurrent OS is much less well-defined and there is no accepted standard regimen.

Several major pharma and biotech companies developing therapies for Osteosarcoma. Currently, Lee Pharmaceutical is leading the therapeutics market with its Osteosarcoma drug candidates in the most advanced stage of clinical development.

Leading Companies in the Osteosarcoma Therapeutics Market Include
• AlaMab Therapeutics
• Zentalis Pharmaceuticals
• Merck Eprova
• Eisai Co Ltd
• George Clinical Pty Ltd
• Y-mAbs Therapeutics
• Jiangsu Hengrui Medicine
• AstraZeneca
• Advenchen Laboratories LLC
• Innovent Biologics
• PersonGen BioTherapeutics (Suzhou)
• Cellectar Biosciences, Inc.
• Merck & Co
• Hutchison Medipharma Limited
• MacroGenics
• Gradalis, Inc.
• Shanghai Pharmaceuticals Holding
• Celgene
• Oncternal Therapeutics
• Valent Technologies
And Many Others

Emerging and Marketed Osteosarcoma Therapies Covered in the Report Include
• KAB001: Lee's Pharmaceutical Limited
• Lenvatinib: Eisai Co Ltd/Merck & Co
• Camrelizumab: Jiangsu Hengrui Medicine
• ZN c3: Zentalis Pharmaceuticals
• ALMB 0168: AlaMab Therapeutics
And Many More

Learn More About the Emerging Therapies and key Companies in the Osteosarcoma Therapeutics Market @
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Osteosarcoma Competitive Intelligence Analysis
4. Osteosarcoma Market Overview at a Glance
5. Osteosarcoma Background and Overview
6. Osteosarcoma Patient Journey
7. Osteosarcoma Epidemiology and Patient Population
8. Osteosarcoma Treatment Algorithm, Current Treatment, and Medical Practices
9. Osteosarcoma Unmet Needs
10. Key Endpoints of Osteosarcoma Treatment
11. Osteosarcoma Marketed Products
12. Osteosarcoma Emerging Therapies
13. Osteosarcoma Seven Major Market Analysis
14. Attribute Analysis
15. Osteosarcoma Market Outlook (7 major markets)
16. Osteosarcoma Access and Reimbursement Overview
17. KOL Views on the Osteosarcoma Market.
18. Osteosarcoma Market Drivers
19. Osteosarcoma Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.

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