Urinary Incontinence - Drug Pipeline Landscape, 2023

Urinary incontinence (UI) is the involuntary leakage of urine. UI happens when the muscles in the bladder that control the flow of urine contract or relax involuntarily, resulting in leaks or uncontrolled urination. The common causes of urinary incontinence include overactive bladder muscles, weakened pelvic floor muscles, nerve damage, interstitial cystitis (chronic bladder inflammation), obstruction, neurological disorders such as multiple sclerosis, stroke, or Parkinson's disease. Urinary incontinence may also be caused by urinary tract infection and constipation.

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Urinary incontinence symptoms include leaking urine during bending, coughing, or exercising; sudden, strong urges to urinate; Leaking urine without feeling any warning sign or urge; Bed-wetting. Diagnosis of UI include urinalysis, blood tests, pelvic ultrasound, postvoid residual (pvr) measurement, stress test, cystogram, cystoscopy and urodynamic testing.

Urinary incontinence can be treated with behavioral techniques, medications, pelvic floor muscle exercises, electrical stimulation, medical devices, interventional therapies and surgery. There are many clinical trials currently ongoing in urinary incontinence drug development. Some of the most promising trials are studying the efficacy of botulinum toxin type A injections for the treatment of urge incontinence.

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Report Highlights
Global Insight Service's, Urinary Incontinence - Drug Pipeline Landscape, 2023 report provides an overview of the Urinary Incontinence pipeline drugs. This report covers detailed insights on Urinary Incontinence drugs under development, assessment by target, mechanism of action, route of administration and molecule type. Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Urinary Incontinence pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.

Methodology
The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.

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Scope
The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clinical trials, and key upcoming milestones are included.

Major pharmaceutical companies are involved in the development of potential drug candidates to improve the treatment of urinary incontinence treatment such as AMDC-USR, Gefapixant, and others. Key players involved in the development of therapies to treat urinary incontinence are Cook MyoSite, Merck & Co, and others. Three drugs are under Phase III clinical trials and four drugs are in Phase II clinical trials and some other drugs are under Phase I, preclinical and discovery stages of development.

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