Atrial Fibrillation Market : Global Market Revenue and Share by Manufacturers

Overview of Global Atrial Fibrillation Market

Atrial fibrillation refers to a type of cardiac arrhythmia distinguished by an abnormal cardiac rhythm caused by a disturbance in heart's electrical system. Atrial fibrillation (AF) is one of the most commonly occurring cardiac rhythm conditions. Being a potentially life threatening disease and expensive to treat, the overall healthcare system views the treatment for this condition as a strategically critical area to address. Increase in global geriatric population is a key factor projected to drive the global atrial fibrillation market during the forecast period.

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Increase in Incidence Rate of Atrial Fibrillation Due to High Prevalence of Disorders Such as Hypertension and Obesity

Cardiovascular disorders, especially atrial fibrillation, are most times a result of hypertension and obesity. According to the Framingham Heart Study, 14% of the atrial fibrillation risks were associated with hypertension, and obesity increased the risk of progression of paroxysmal atrial fibrillation to permanent atrial fibrillation by 45% to 50%. The prevalence of these disorders is rising due to socio-economic factors such as lifestyle induced dietary and other habits (excessive alcohol consumption and smoking).
According to WHO estimates, 35% of adults aged 20 years and above were overweight. The global prevalence of obesity has almost doubled since 1980 and is expected to rapidly increase in future. Moreover, the prevalence of hypertension in 2008 was stood at 1 billion. The WHO suggests that in 2008, the prevalence of hypertension in low, middle, and upper middle income countries was 40% and 35% in high income countries. High and rise in prevalence of these disorders is expected to propel the global atrial fibrillation market during the forecast period.

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Promising Results of Clinical Trials Aimed at Treating Atrial Fibrillation to Boost Market Growth

The combined pharmacological therapy is a new and promising treatment option for atrial fibrillation. The combined pharmacological therapy has exhibited encouraging results in clinical trials and would help in catering to the unmet medical needs in those suffering from atrial fibrillation. This factor is projected to drive the global atrial fibrillation market. Additionally, research results on animal mode for the combined therapy yielded favorable and synergistic anti-arrhythmic results.

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The clinical trials aimed at testing the effect of a combined therapy involving Multaq and Ranexa was unveiled at the Boston Atrial Fibrillation Symposium. This clinical trial was titled HARMONY and enrolled around 150 patients with non-permanent atrial fibrillation and with implanted pacemakers. Preclinical data revealed by this study suggest that this combination therapy is well positioned in the current anti-arrhythmic drugs segment, especially on the grounds of safety and efficacy.

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Stringent FDA, CE, and European Medicines Agency Product Approval Regulations to Hamper Market

Atrial fibrillation devices such as implantable pacemakers, defibrillators, and catheters are regarded as class III high risk medical devices by the U.S. FDA. Therefore, these devices undergo rigorous safety and efficacy tests prior to receiving an approval. Moreover, these devices need to obtain a premarket approval, which is an expensive and lengthy affair. Atrial fibrillation drugs are no exception to these stringent regulations and hence, need to undergo strictly monitored safety and efficacy tests. Failure to comply with the regulations laid down by the FDA and European Medicines Agency will result in a product recall or clinical trial termination. For instance, termination of PALLAS study and issuance of safety alerts by the FDA for Multaq.
Increase in Geriatric Population to Drive Global Market

Surge in global geriatric population increases the incidence rate of atrial fibrillation. This acts as a major driver for the global atrial fibrillation market. Additionally, favorable results exhibited by clinical trials promoting combined pharmacological therapy such as the HARMONY trial and rise in prevalence of disorders causing atrial fibrillation such as hypertension and obesity are projected to propel the global atrial fibrillation market.

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