Chromatography Resin Industry worth $3.8 billion by 2027 | Key players Bio-Rad Laboratories, Merck KGaA, Danaher Corp, Tosoh Cor, Bio-Works Technologies AB

According to recent market research "Chromatography Resin Market by Type, Technique (Ion Exchange, Affinity, Hydrophobic Interaction, Size Exclusion, Mixed Mode), Application (Pharmaceutical & Biotechnology, Food & Beverage) and Region - Global Forecasts to 2027", The global chromatography resin market will grow to USD 3.8 billion by 2027, at a CAGR of 8.0% from USD 2.6 billion in 2022. This growth is primarily triggered by the increasing demand for therapeutic antibodies. Almost all the major pharmaceutical companies have undertaken R&D on therapeutic antibodies. In the purification of monoclonal antibodies, anionic impurities such as nucleic acids and endotoxins are removed through anion exchange chromatography. Thus, the integral role of chromatography techniques in the development of monoclonal antibodies is expected to drive the chromatography resin market.

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Natural polymer used in chromatography techniques is extracted from living cells such as plant and bacteria cells. Agarose, cellulose, and dextran are the natural polymers that are most commonly used as resins in chromatography applications. Chitosan is also used as a resin in a few ion chromatography applications. Most of these natural polymeric resins are polysaccharides. The major advantage of these natural polymers is their hydrophilic nature, as they have a large number of hydroxyl groups in their structure. These factors drive the demand for natural polymer chromatography resin.

IEX chromatography accounted the largest share in the global chromatography resin market, in terms of volume, in 2021. Ion exchange chromatography is a technique by which molecules are separated based on the reversible ionic interactions between molecules of analyte and the oppositely charged stationary resin. The stationary resin is typically a cross-linked polymer matrix (often agarose) with a functional group attached to it. The largest share of IEX chromatography, in terms of volume, can be attributed to the increasing demand for this technique in the pharmaceutical industry.

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The chromatography resin market is estimated to grow to USD 3.8 billion by 2027 from USD 2.6 billion in 2022, at a CAGR of 8.0%. Growing pharmaceuticals & biopharmaceutical R&D activities is expected to support the growth of the chromatography resin market. However, lack of adequate skilled professionals is restraining the growth of the market. On the other hand, increasing demand for disposable pre-packed columns has created opportunities for manufacturers.

Bio-Rad Laboratories Inc. (US), Merck KGaA (Germany), Danaher Corporation (US), Tosoh Corporation (Japan), Bio-Works Technologies AB (Sweden), Avantor Performance Materials, Inc. (US), Mitsubishi Chemical Corporation (Japan), among others are the major players in this market.

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Bio-Rad Laboratories, Inc. is a multinational manufacturer and worldwide distributor of life science research and clinical diagnostics products. Bio-Rad operates their business through three reportable segments, namely, life science, clinical diagnostics, and others. Both clinical diagnostics and life science operate worldwide. The company offers chromatography resins through the life science segment. The company has direct distribution channels in over 35 countries outside the US through subsidiaries whose focus is sales, customer service and product distribution. Sales efforts are supplemented by distributors and agents in some locations outside and inside these 35 countries such as North America, South America, Latin America, Europe, and Asia Pacific.

The Danaher Corporation is an US-based globally diversified conglomerate, which designs, manufactures, and markets professional, medical, industrial, and commercial products and services. Danaher Corporation operates their business through three reportable segments, namely, life sciences, diagnostics, and environmental & applied solutions. Danaher is offering chromatography resins through its acquired standalone company named, Cytiva. The company operate in 40 countries and territories covering Europe, Asia, North and Latin America, and the Middle East.

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