openPR Logo
Press release

Blue California Files Patent on the Use of Ergothioneine as a Support for Oxidative Stress Related Health Conditions, including COVID-19

07-15-2020 10:18 AM CET | Health & Medicine

Press release from: Blue California

Blue California Files Patent on the Use of Ergothioneine as

Blue California’s proprietary Ergothioneine formulations and its potential amelioration and/or beneficial effects in oxidative stress conditions is the subject of its earlier patent filing in February of this year. Now, Blue California has filed a second patent application on the potential role of its Ergothioneine formulations for oxidative stress indications presented in viral infections such as COVID-19 as well as common inflammatory disease conditions.

Rancho Santa Margarita, Calif. and Bedford, Mass. (July 14, 2020) — Blue California, a science-based, innovative ingredient solution provider, has just filed for a patent on therapeutic uses of the ingredient Ergothioneine. This follows Blue California’s Feb. 2020 patent application reporting the discovery that ergothioneine inhibits the shortening of telomeres typically associated with oxidative stress. Specifically, it claims that Ergothioneine can mitigate oxidative stress triggering the inflammatory response in many chronic conditions associated with heart disease, diabetes and cancer. Also, in support of other oxidative conditions associated with oxidative stress including COVID-19 as well as other viral diseases.

“Blue California has been at the forefront of research and development regarding Ergothioneine using our branded ingredient ErgoActive®,” stated Dr. Priscilla Samuel, chief science officer at Blue California, “We have found through our research that Ergothioneine has tremendous potential to combat oxidative stress and health conditions associated with it.”

Ergothioneine is a naturally occurring amino acid normally provided to the body from dietary sources such as mushrooms in which it is particularly rich. Humans produce a highly specific transport protein called OCTN1 for Ergothioneine, leading many to speculate about its importance to human health.1 It is a super antioxidant, and renowned scientist Dr. Bruce Ames has even proposed classifying it as a “longevity vitamin.”2

“The possibilities for ErgoActive to be incorporated in an immune health supplement or in a functional food or beverage are immense,” commented Katie Ferren, vice president of sales and marketing at Blue California. “This opens up the door for support in some exciting health applications.”

Blue California is one of the only companies in the United States that has received a no-objection from the FDA to its GRAS notification on Ergothioneine with their branded ingredient ErgoActive. The company exclusively manufactures and distributes ErgoActive for Conagen, a greater Boston area biotechnology company with a large portfolio of products for the food, nutrition, and pharma markets. Vice President of Innovation at Conagen Dr. Casey Lippmeier explains, “ErgoActive is an ideal nutrient and we produce it with a proprietary fermentation process. Ours is the only sustainable, commercially available source of Ergothioneine which does not rely on chemical synthesis or extraction from mushrooms.”

Blue California and Conagen are eager for next steps. “Blue California recently invested in both in vitro and in vivo research of ErgoActive. We will be studying how Ergothioneine supplementation can support various health benefits, including immune health. We also look forward to clinical studies that further test and demonstrate these novel benefits included in our patent application, and in the emerging scientific literature,” said Dr. Samuel.

ErgoActive® is a registered trademark of Blue California, Inc.

1. Beelman, R, Kalaras, MD & Richie, JP. Micronutrients and bioactive compounds in mushrooms: a recipe for healthy aging? Nutr Today 2019; (54): 16–22
2. Ames BN. Prolonging healthy aging: longevity vitamins and proteins. PNAS.2018;115(43):10836–44.


30111 Tomas, Rancho Santa Margarita, Califoria, 92688, USA

About Blue California and Conagen
Blue California provides innovative solutions to global partners in the development and manufacture of botanical extracts and other unique ingredients. With more than 20 years of innovation, our ingredients are used in commercial products and applications in the industries of nutrition, personal care, healthy aging and wellness, functional food and beverage, and beauty.

Conagen is making the impossible possible. Our scientists and engineers are bettering humankind and the world by employing advanced synthetic biology tools for the bioproduction of high-value ingredients for food, nutrition, flavor and fragrance, pharmaceutical, and renewable materials industries.

This release was published on openPR.

Permanent link to this press release:

Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Blue California Files Patent on the Use of Ergothioneine as a Support for Oxidative Stress Related Health Conditions, including COVID-19 here

News-ID: 2090057 • Views: 502

More Releases from Blue California

Blue California To Start Production of New Nature-based Bitter Blocker Technolog …
Food and beverage brands, and manufacturers will now have access to novel flavor technology for reducing bitter notes. Rancho Santa Margarita, Calif. and Bedford, Mass. (Sept. 23, 2020) --- Blue California, a vertically integrated technology company that designs and produces sustainable ingredient solutions for the food, beverage, and supplement industry, announced jointly, with biotech innovator Conagen, the patent filing for a new, nature-based bitter blocker technology to improve

More Releases for Calif

NCMMH Hosts Lobby Day & Briefing on Capitol Hill May 17th
For Immediate Release — The National Coalition for Maternal Mental Health (NCMMH) is spearheading a Lobby Day and briefing on Capitol Hill, Tuesday, May 17, to support the Bringing Postpartum Depression Out of the Shadows Act of 2015, which will provide for better education about and treatment of maternal mental health issues, as well as increased access to appropriate care. House of Representatives Bill #HR3235, introduced by Congresswoman Katherine Clark (D-MA),
Lori Ballen to teach Ballen Method Live in Stockton, Calif. on May 31 – June 2 …
March 25, 2016 – FOR IMMEDIATE RELEASE Lori Ballen, digital strategist, Internet marketer, public speaker, inventor of The Ballen Method and founder of Ballen Brands, a Las Vegas marketing company, is scheduled to teach a three-day class titled The Ballen Method Live, a class on Internet Marketing, in Stockton, Calif. From May 31 – June 2, 2016, at Keller Williams Realty Stockton located at 3133 West March Lane, Suite 1060, Stockton,
Eolas Technologies Reaches Settlement with New Frontier Media in Texas Patent In …
TYLER, Texas – Internet technology provider Eolas Technologies Inc. has reached a settlement agreement with Boulder, Colo.-based New Frontier Media Inc. (Nasdaq: NOOF) in a Texas patent infringement lawsuit. Under the agreement, New Frontier will license two Eolas patents that enable Internet browsers to host embedded interactive applications. The settlement resolves all of Eolas’ legal claims against New Frontier in Eolas Technologies Inc. v. Adobe Systems Inc., et al., No. 6:09-cv-446.
Eolas Technologies Announces JPMorgan Settlement in Patent Lawsuit
TYLER, Texas – Internet technology provider Eolas Technologies Inc. has reached an agreement with JPMorgan Chase & Co. (NYSE: JPM) to settle a Texas patent infringement lawsuit related to two Eolas patents that enable Internet browsers to host embedded interactive applications. The settlement resolves Eolas’ legal claims against JPMorgan in Eolas Technologies Inc. v. Adobe Systems Inc., et al., No. 6:09-cv-446. The terms of the settlement are confidential. The lawsuit remains
TEDxGoldenGateED Bringing Focus on Compassion in Education to the Craneway Pavil …
Prospect Sierra and U.C. Berkeley’s Greater Good Science Center are teaming to host a TEDx conference on compassion in education ( on Saturday, June 11 at the Craneway Pavilion in Richmond, Calif. Tickets are available now via the website. TEDxGoldenGateED programming is focused on compassion — the sympathetic awareness of another’s distress, coupled with the desire to alleviate their suffering. Compassion is at the heart of the world’s ethical
Elements Therapeutic Massage to Debut Largest Store in Fountain Valley, Calif.
National franchise enters market with bigger studio and aggressive plans for the region. FOUNTAIN VALLEY, Calif. - Nov. 12, 2009 - elements therapeutic massage, inc., a national massage therapy franchisor, has announced that it will debut a new store next month in Fountain Valley, Calif. The studio, located at 18303 Brookhurst St., will be the first franchise in that market for the fast-growing massage chain and is almost twice the size