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Synergy Pharmaceuticals Sues Rival Ironwood Pharmaceuticals in Drug Patent Case

12-14-2011 04:56 AM CET | Health & Medicine

Press release from: Synergy Pharmaceuticals, Inc.

NEW YORK - Synergy Pharmaceuticals, Inc. (Nasdaq:SGYPD, SGYPU), a developer of new drugs to treat gastrointestinal (GI) disorders and diseases, announced today that it has filed a lawsuit in New York State Supreme Court against Ironwood Pharmaceuticals, Inc. (Nasdaq:IRWD) and its Chief Scientific Officer and Senior VP of R&D, Dr. Mark G. Currie.

The lawsuit alleges that after European Patent 1,379,224 was granted to Synergy but prior to issuance, Ironwood and Dr. Currie opposed the patent before the European Patent Office and presented to the European Patent Office and the United States Patent and Trademark Office, data and arguments that were false, contradictory, inaccurate and misleading.

In its complaint, Synergy accuses Ironwood and Dr. Currie of, among other things, unfair competition, fraud and unjust enrichment and seeks $500 million in actual and punitive damages.

Synergy's proprietary drug candidate plecanatide is a synnthetic analog of the human gastrointestinal hormone uroguanylin, and functions by activating the guanylate cyclase C receptor on epithelial cells of the GI tract.

Synergy completed a Phase I study of plecanatide in healthy volunteers and a Phase IIa clinical trial in patients to treat chronic idiopathic constipation (CIC) patients. In October, 2011, Synergy initiated dosing of patients in a major Phase II/III clinical trial of plecanatide in CIC patients. Plecanatide is also being developed to treat constipation-predominant irritable bowel syndrome, with the first trial in IBS-C patients planned for 2012.

Synergy's second GC-C agonist SP-333 is currently in pre-clinical development to treat inflammatory bowel diseases.

Contact:
Alex Michelini, Synergy Media representative
michelinialex@aol.com
The Promotion Factory
5 E. 19th Street
New York, NY 10003
212-217-9065
www.thepromofact.com

Synergy is a biopharmaceutical company focused on the development of new drugs to treat gastrointestinal disorders and disease.

420 Lexington Avenue, Suite 1609
New York, NY 10170
Contact: Alex Michelini, media representative
201-831-0171
michelinialex@aol.com

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