Nasal Drug Delivery Systems Market Five Years Forecast Skeleton With Key Companies GlaxoSmithKline, AstraZeneca, Johnson & Johnson, Pfizer, Baxter International

The global nasal drug delivery systems market size is estimated to be valued at US$ 48.1 billion in 2018 and is expected to witness a CAGR of 6.3% over the forecast period (2018 – 2026).

Novel drug delivery systems are one of the fastest growing segment in the pharmaceutical industry. Nasal is a transmucosal drug delivery system, used to administer drug through nasal cavity. Numerous studies are conducted to study the systemic bioavailability of drug and on nasal administration of vaccine, peptide and hormonal therapy, and other drugs which are usually delivered by parenteral route.

Growth in nasal drug delivery system market is attributed to high advantages of nasal administration and increasing innovative nasal drug delivery systems. Moreover, expanding therapeutic application is expected to drive growth of the nasal drug delivery systems market. For instance, number of pharmaceutical and biopharmaceutical companies are adopting nasal drug delivery system for the treatment of acute migraine, pain management, Alzheimer disease etc. For instance, in 2016, Lannett Company, Inc. received Abbreviated New Drug Application (ANDA) approval from the U.S. FDA for its Sumatriptan Nasal Spray intended for the treatment of migraine. Moreover, in June 2018, Impax Specialty Pharma, Inc., a specialty pharmaceutical company, received US FDA approval for Zomig Nasal Spray to treat acute migraine in patients aged 12 years and above.

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Furthermore, in 2017, FDA approved OptiNose U.S. Inc.’s Xhance, which is a novel combination of drug and device to deliver fluticasone propionate to treat nasal polyps. Such product launches with diverse therapeutic application are augmenting the nasal drug delivery systems market growth.

Major advantages of nasal drug delivery is that, the drug circumvents hepatic first-pass metabolism, leading to high bioavailability as compared to drug administered orally. On the other hand, parenteral route of administration is also inconvenient for long term therapeutic treatment.

Nasal cavity being highly vascular enhances the drug absorption resulting in rapid onset of action. Moreover, ease of administration coupled with non-invasive method is driving adoption of nasal drug delivery systems, in turn propelling nasal drug delivery systems market growth. However, limitations associated with nasal drug delivery system such as histological toxicity or lesser area of absorption as compared to orally administered drug hinders the nasal drug delivery systems market growth.

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