Press release
Amifostine Market 2019 - Clinigen Group, Sun Pharmaceutical, Taj Pharmaceuticals, Merro Pharmaceutical, Luye Pharma, Mingren Pharma
Amifostine Market
Amifostine is a pro-drug which is activated to the free thiol metabolite at the tissue site. The thiol metabolite is responsible for most of the cytoprotective and radioprotective properties of amifostine. It is readily taken up by cells where it binds to and detoxifies reactive metabolites of platinum and alkylating agents as well as scavenges free radicals. Other possible effects include inhibition of apoptosis, alteration of gene expression and modification of enzyme activity. Healthy cells are preferentially protected because amifostine and metabolites are present in healthy cells at 100-fold greater concentrations than in tumour cells.
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Consumption of amifostine mainly concentrates in North America. In 2016, the region consumed 780 K Unit, holding about 52% market share globally. The follower is Asia-Pacific, with about 41% consumption share.
The market is relatively concentrated and there are just a few suppliers in the market, such as Clinigen Group, Sun Pharmaceutical, Merro Pharmaceutical and so on. Clinigen Group acquired the business from AstraZeneca in the year of 2014 and signed an agreement with Cumberland in the year of 2016. Under the agreement, Cumberland acquired the exclusive rights to commercialize Ethyol in the United States. Merro Pharmaceutical own the largest sales share in China.
Amifostine shows good effect in reducing harmful effects of cisplatin chemotherapy on kidneys in women treated for advanced ovarian cancer as well as relieving dry mouth problems (xerostomia) with head and neck cancer patients undergoing radiation treatment. It is estimated that the amifostine market will keep upward tendency and to be worthy of 49.99 million USD in 2023 globally.
The global Amifostine market is valued at 48 million US$ in 2018 is expected to reach 57 million US$ by the end of 2025, growing at a CAGR of 2.2% during 2019-2025.
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This report focuses on Amifostine volume and value at global level, regional level and company level. From a global perspective, this report represents overall Amifostine market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.
At company level, this report focuses on the production capacity, ex-factory price, revenue and market share for each manufacturer covered in this report.
The following manufacturers are covered:
• Clinigen Group
• Sun Pharmaceutical
• Taj Pharmaceuticals
• Merro Pharmaceutical
• Luye Pharma
• Mingren Pharma
Segment by Regions
• Europe
• China
• Japan
• North America
Segment by Type
• 500mg/Dose
• 400mg/Dose
Segment by Application
• Others
• Head and Neck Cancer Adjuvant Therapy
Table of Contents
Executive Summary
1 Amifostine Market Overview
2 Global Amifostine Market Competition by Manufacturers
3 Global Amifostine Production Market Share by Regions
4 Global Amifostine Consumption by Regions
5 Global Amifostine Production, Revenue, Price Trend by Type
6 Global Amifostine Market Analysis by Applications
7 Company Profiles and Key Figures in Amifostine Business
8 Amifostine Manufacturing Cost Analysis
9 Marketing Channel, Distributors and Customers
10 Market Dynamics
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Amifostine (Ethiofos) is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents. It is marketed by Clinigen Group under the trade name Ethyol.
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