Danaher Corporation, Bio-Rad Laboratories, GenScript, Novasep, Purolite Life Sciences Profiled in Protein A Resins Market
Demand for monoclonal antibodies is increasing rapidly from past few years due to its wide range of applications in the management of chronic diseases such as cancer. In response to increasing demand, manufacturers are optimizing their production capacities and launching new plants for large scale production of monoclonal antibodies. Several monoclonal antibodies have already been approved while many are still in the late phase of clinical trials. Increasing production of monoclonal antibodies will escalate the need of protein A resins for antibody purification on large scale impacting industry growth.
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Immunoprecipitation application segment of protein A resins market is forecasted to witness robust growth rate over forthcoming years. Immunoprecipitation is widely applicable in research and development sector. As protein A resins are used in immunoprecipitation technique its demand is forecasted to go hand in hand with increasing demand for immunoprecipitation.
Company profiled in this report based on Business overview, Financial data, Product landscape, Strategic outlook & SWOT analysis:
• Danaher Corporation
• Bio-Rad Laboratories
• Purolite Life Sciences
• GE Healthcare
• Repligen Corporation
• Takara Bio Inc.
• Thermo Fisher Scientific
• Agarose Bead Technologies ABT
• EMD Millipore
• Tosoh Bioscience, Inc.
Recombinant protein A resins segment of protein A resins market dominated the industry over forecast timeframe. Recombinant protein A is formulated in E.Coli and functions same as that of natural protein A resins. However, recombinant form of protein is preferred where other production source offers less non-specific binding. Natural protein A resins provides high capacity antibody purification but are sensitive to alkaline conditions. Due to sensitivity to alkaline conditions, cleaning in place (CIP) of natural a protein resins with 0.1M or 1M NaOH is not feasible. Thus, alternative CIP must be used that in turns increase the overall cost of procedure.
Biopharmaceutical firms uses protein A resins extensively for large scare purification of monoclonal antibodies. Production of therapeutic monoclonal antibodies by biopharmaceutical firm is forecasted to rise to cater to its increasing demand. With the rising production of monoclonal antibodies, demand for protein A resins will grow for the large-scale purification.
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U.S. accounted for largest regional share in 2017 due to robust research and development in the field of drug discovery and ongoing inflow of approved monoclonal antibodies in the protein A resins market. Technological advancements coupled with the availability of funding for research on novel therapies will further render significant positive impact growth.
Protein A Resins Market by Application
o Antibody Purification
Protein A Resins Market by Product
o Natural Protein A
o Recombinant Protein A
Protein A Resins Market by Product
o Agarose-based matrix
o Glass or silica gel-based matrix
o Organic polymer—based matrix
Protein A Resins Market by Product
o Biopharmaceutical companies
o Clinical research laboratories
o Academic research institutes
o Contract research organizations
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