Press release
Hereditary Orotic Aciduria treatment Market Segments, Supply & Demand, Competition & Companies involved, Value Chain, Opportunity Assessment 2025
The report "Hereditary Orotic Aciduria treatment Market - Global Industry Trend Analysis 2012 to 2016 and Forecast 2017 - 2025" gives complete assessment of the latest trends, challenges of market.The objectives of this study are as follows:
• To define, describe, and forecast the " Hereditary Orotic Aciduria treatment " market by type, application, component, delivery model, end user, and region
• To provide detailed information regarding major factors influencing market growth (drivers, restraints, opportunities, and industry-specific challenges)
• To analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
• To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
• To forecast the market size of market segments with respect to the four key regions: North America, Europe, Asia, and the Rest of the World (RoW)
• To strategically profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
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Hereditary orotic aciduria is a condition refers to an excessive excretion of orotic acid in the urine. Orotic acid is an intermediate product produced during the pyrimidine synthesis pathway. Hereditary orotic aciduria is a rare autosomal recessive disorder. Hereditary oratic disorder may be caused by a deficiency in enzyme UMPS. UMPS is a bifunctional protein that consists of the enzyme activities of orotate phosphoribosyltransferse and orotidine 5-phosphate decarboxylase. Hereditary oratic aciduria is also known as uridine monophosphate synthase deficiency. This rare congenital autosomal recessive disorder of pyrimidine metabolism is caused by defect in uridine monophosphate synthase. Hereditary oratic aciduria is one of the rare metabolic disorder, which has been reported in approximately 20 patients worldwide according to FDA. The symptoms of the disease include growth retardation, mental retardation, megaloblastic anemia, immunodeficiency and high level of oratic acids in urine. The inability to convert orotic acid results in body being unable to normally synthesize uridine, a necessary component of RNA which leads to failure to thrive. Hereditary orotic aciduria patients are administered with cytidine monophosphate and uridine monophosphate to reduce urinary orotic acid and anemia. Patient may also administrated with uridine, which converted into UMP and provide a source of pyrimidine for the body.
Hereditary Orotic Aciduria treatment Market: Drivers and Restraints
Hereditary orotic aciduria treatment market shows growth in forecast period due to increasing healthcare awareness and healthcare expenditure. Hereditary oratic aciduria is rare autosomal disorder so manufacture are finding new solution for treatment of disease. Increasing research and development in pharmaceutical and molecular science is also a factor which increase growth of hereditary orotic aciduria treatment market.
Hereditary Orotic Aciduria treatment Market: Segmentation
On the basis of drug type the Hereditary Orotic Aciduria treatment market can be segmented as
• Cytidine monophosphate
• Uridine monophosphate
On the basis of indication the Hereditary Orotic Aciduria treatment market can be segmented as:
• Type I
• Type II
On the basis of distribution channel the Hereditary Orotic Aciduria treatment market can be segmented as:
• Hospital pharmacies
• Retail pharmacies
• Online
• Others
Hereditary Orotic Aciduria treatment Market: Overview
Hereditary orotic aciduria treatment market is growth because of increase in clinical trials to develop drugs for proper treatment of this disorder. Orotic acid from the de novo pyrimidine pathway that cannot be converted to UMP is excreted in urine, accounting for common name of disorder, orotic aciduria. Uridine triacetate is one the effective drug used for hereditary orotic aciduria treatment. Uridine triacetate majorly orally administered. Uridine triacetate is a pyrimidine analog. These drug works by replacing the uridine that cannot be normally produced in patients with hereditary orotic aciduria. Hereditary orotic aciduria is unique because was through of unique because loss of two enzymes. It is now known that these activities resides in different domains of single polypeptide coded by a single gene. Hereditary orotic aciduria patients have a macrocytic hypochromic megloblastic anemia and orotic acid crystalluria. Majority of patients have been treated with uridine with good effects in majority. Some of the patients require continued therapy.
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Hereditary Orotic Aciduria treatment Market: Region-wise Outlook
In terms of geography, hereditary orotic aciduria treatment market has been divided into five regions including North- America, Asia- Pacific, Middle-East & Africa, Latin America, and Europe. North America dominated the global hereditary orotic aciduria treatment market as followed by Europe. North America region dominates the hereditary orotic aciduria market due their increasing research and development in pharmaceutical industry. In Asian Pacific, India and China will be the main market for the growth of the hereditary orotic aciduria treatment market.
Hereditary Orotic Aciduria treatment Market: Key Market Participants
Example of some of the market participants in global hereditary orotic aciduria treatment market identified across the value chain includes Merck & Co. Inc., Cyman Chemical and Wellstat Therapeutics Corporation are leading companies in the market which have the highest contribution to hereditary orotic aciduria treatment market.
MRR.BIZ has been compiled in-depth market research data in the report after exhaustive primary and secondary research. Our team of able, experienced in-house analysts has collated the information through personal interviews and study of industry databases, journals, and reputable paid sources.
The report provides the following information:
• Tailwinds and headwinds molding the market’s trajectory
• Market segments based on products, technology, and applications
• Prospects of each segment
• Overall current and possible future size of the market
• Growth pace of the market
• Competitive landscape and key players’ strategies
The main aim of the report is to:
• Enable key stakeholder’s in the market bet right on it
• Understand the opportunities and pitfalls awaiting them
• Assess the overall growth scope in the near term
• Strategize effectively with respect to production and distribution
MRR.BIZ is a leading provider of strategic market research. Our vast repository consists research reports, data books, company profiles, and regional market data sheets. We regularly update the data and analysis of a wide-ranging products and services around the world. As readers, you will have access to the latest information on almost 300 industries and their sub-segments. Both large Fortune 500 companies and SMEs have found those useful. This is because we customize our offerings keeping in mind the specific requirements of our clients.
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