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Immune Anti-Inhibitor Market Estimated Growth Top Key Players Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring.

11-27-2018 07:41 AM CET | Health & Medicine

Press release from: Coherent Market Insights

Immune Anti-Inhibitor Market

Immune Anti-Inhibitor Market

Immune Anti-Inhibitor Market is expected to have a highly positive outlook for the next five years 2018–2026 according to a recently released Immune Anti-Inhibitor Market research report. The report has been added in his large database by Coherent Market Insights.

The U.S. Food & Drug Administration (FDA) approved Emicizumab (Hemlibra) once – weekly subcutaneous therapy for haemophilia A with inhibitors in September 2017. Emicizumab is a monoclonal antibody designed to facilitate blood clotting process by combining factors IXa and X. Moreover, the Center for Disease Control and Prevention (CDC) is examining the etiology of the haemophilia with inhibitors, which could help in development of novel therapies to boost growth of the immune anti-inhibitor market. Pipeline for haemophilia with inhibitors is also promising as few of the manufacturers are working on novel therapies for the condition. One such organization Catalyst Biosciences has a Factor VIIa marzeptacog alfa (activated) in the clinical trials for haemophilia A or B with inhibitors. Moreover, Bioverativ Inc., a Sanofi S. A.'s subsidiary has FVIIIa mimetic bispecific antibody under studies for haemophilia A with inhibitors. Multiple products are pipeline which are expected to receive approval over the forecast period, this in turn is projected to boost growth of the immune anti-inhibitor market over the forecast period.

Download PDF Brochure of This Business Research Report: https://www.coherentmarketinsights.com/insight/request-pdf/1519

Researchers are working on analyzing the risks associated with use of replacement factors, as in which replacement factors are more prone to facilitate development of antibodies. For instance, World Federation of Haemophilia (WFH) announced results from study published in journal ‘Blood’ in 2014, which demonstrated higher incidence of inhibitor development after treatment with Kogenate FS/Bayer/Helixate NexGen replacement factor. The World Federation of Haemophilia has requested the U.S. Food & Drug Administration and the European Medicine Agency (EMA) to examine the data. Such studies are expected to reduce the instances of haemophilia with antibodies.

Furthermore, therapies such as Immune Tolerance Induction (ITI) which involve continuous treatment with replacement factors till they are no longer considered as foreign bodies by inhibitors are expected to restrain the growth of the market.
Immune system of haemophilia patients’ produces antibodies called as inhibitors, which acts against the administered therapy. Haemophilia patients are administered either plasma-derived or recombinant replacement blood factor concentrates as medication therapy, which help in blood clotting. However, the inhibitors falsely target replacement factor concentrates as a foreign substance. These antibodies are developed after the patient has been administered with blood factor FVIII concentrate. Inhibitors act after 10 to 20 days of first exposure to factor replacement therapy. Most of these inhibitors remain in the blood for short time and disappear without treatment. However, more persistent inhibitors is a serious adverse event with respect to treatment of Haemophilia A. Commercially available anti-inhibitor coagulant complex includes FEIBA and FEIBA VH Immuno.

Request For Customization Of This Business Research Report: https://www.coherentmarketinsights.com/insight/request-customization/1519

Competitive Analysis

Key players operating in global immune anti-inhibitor market include Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring.

Immune Anti-Inhibitor Market Taxonomy-

The global immune anti-inhibitor market is segmented on the basis of product type, distribution channel, and geography.

By Product Type-
Recombinant
Plasma-Derived
Others

By Distribution Channel-
Hospital Pharmacies
Online Pharmacies
Retail Pharmacies

By Geography-
North America
Europe
Asia Pacific
Latin America
Middle East
Africa

About Coherent Market Insights:

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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