openPR Logo
Press release

The Hyper IgM Foundation Presents $15,000 Grant to Dr. Antonio Condino-Neto at University of São Paulo, Brazil

10-24-2018 10:35 AM CET | Health & Medicine

Press release from: Hyper IgM Foundation, Inc.

The Hyper IgM Foundation

The Hyper IgM Foundation

NEW YORK, New York—The Hyper IgM Foundation is delighted to announce it has awarded $15,000 to Dr. Antonio Condino-Neto at University of São Paulo, Brazil, to support research into Novel Immunopathological Mechanisms of X-Linked Hyper IgM Syndrome.

These funds will support the continued work in search of additional treatments for X-Linked Hyper IgM Syndrome (X-HIGM). Currently, the only known cure for X-HIGM is a stem cell transplant. There are no curative treatment options, however, for those X-HIGM patients without an HLA match or those with chronic infections or other conditions that make allogeneic stem cell transplant too risky. Lifelong treatment with immunoglobulin replacement therapy (IVIG) and prophylaxis antibiotics is necessary; however, even with these treatments, the survival rate for X-HIGM patents is low. Dr. Condino-Neto plans to use the grant to “investigate the mechanisms of response to infections focusing on mechanisms that precede the effector response in the infectious site.” In addition, Dr. Condino-Neto will investigate whether the in vitro interferon- gamma (IFN-γ) treatment, known to boost phagocyte activity, has the potential to improve these cells’ response. Dr. Condino-Neto’s work has the potential to advance the knowledge associated with the study of the effect of IFN-γ treatment can substantiate the development of new therapeutic strategies aimed at improving the quality of life of patients affected by this syndrome.

In the next year, the funding from the grant will help cover research into the immunological mechanisms involved in the high susceptibility to fungal infections showed by patients with X-HIGM, focusing on cellular functions that precede the action at the infectious site, and investigating whether neutrophils in vitro treatment with IFN-γ has the potential to improve the response of these cells.

Hyper IgM affects only 1 in 1,000,000 individuals. The life-threatening genetic mutation severely compromises the immune system and its ability to produce responses to pathogens such as bacteria and viruses. Chronic neutropenia, which is manifested cyclically or intermittently, affects approximately 70% of patients with X-HIGM, indicating severe disorders in the granulopoiesis process. The characterization of the immunological mechanisms affected by the lack of CD40-CD40L interactions and the effect of the IFN-γ treatment under these conditions bring up new perspectives for the development of therapeutic strategies that aim to improve the quality of life of the patients affected by this syndrome.

The Hyper IgM Foundation’s mission is to improve the treatment, quality of life and long-term outlook for children and adults living with Hyper IgM. The Foundation gives families coping with Hyper IgM the opportunity to connect with other patient families to gain both knowledge and support.

The Hyper IgM Foundation fundraises all year long in order to fund progress in research for a cure. Last year alone, the Foundation raised over $68,000. The goal is to see the understanding of and treatment for Hyper IgM Syndrome moved forward and that is where help is needed.

For more information about Hyper IgM Syndrome, or to support the cause, please visit www.hyperigm.org/donate.

If you have any questions or interest in supporting our foundation, please email info@hyperigm.org.

Hyper IgM Foundation, a non-profit organization, was founded in 2015 by dedicated parents, healthcare professionals and friends. Our mission is to improve the treatment, quality of life and the long term outlook for children and adults living with Hyper IgM through research, support, education, and advocacy to families and patients.

Hyper IgM Foundation
215 W101st Street. Suite 7B
New York, NY 10025
United State of America
www.hyperigm.org

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release The Hyper IgM Foundation Presents $15,000 Grant to Dr. Antonio Condino-Neto at University of São Paulo, Brazil here

News-ID: 1323228 • Views: 236

More Releases from Hyper IgM Foundation, Inc.

Hyper IgM Foundation Announces $30,000 In Research Grants:
FOR IMMEDIATE RELEASE: January 21, 2020. The Hyper IgM Foundation is proud to announce the availability of seed grant funding for researchers interested in the advancement of a cure for Hyper IgM Syndrome. The intent of these grants is to accelerate scientific work focused on improving the treatment, quality of life, and long-term outlook for patients with Hyper IgM. Special consideration will be given to well-defined projects focused on gene
Hyper IgM Foundation founders launch $15,000 fundraising campaign in honor of th …
Hyper IgM Foundation founders, Akiva and Amanda Zablocki, launch $15,000 fundraising campaign in honor of their son's 3rd Transplantversary. Idan Zablocki will celebrate the 3rd birthday of his new immune system on July 19th, one day before his actual 7th birthday. While Idan no longer needs to worry about germs and infections and can live a normal life, the Zablockis continue to dedicate their time and resources to finding a cure
Hyper IgM Foundation Announces $25,000 In Research Grants:
FOR IMMEDIATE RELEASE: February 19, 2019. The Hyper IgM Foundation is proud to announce the availability of seed grant funding for researchers interested in the advancement of a cure for Hyper IgM Syndrome and primary immunodeficiency disorders. The intent of these grants is to accelerate scientific work focused on improving the treatment, quality of life, and long-term outlook for patients with Hyper IgM. Special consideration will be given to well-defined projects
Hyper IgM Foundation Research Grants:
FOR IMMEDIATE RELEASE: February 05, 2018. The Hyper IgM Foundation is proud to announce the availability of seed grant funding for researchers interested in the advancement of a cure for Hyper IgM Syndrome and primary immunodeficiency disorders. The intent of these grants is to accelerate scientific work focused on improving the treatment, quality of life, and long-term outlook for patients with Hyper IgM. Special consideration will be given to well-defined projects

All 5 Releases


More Releases for Foundation

PRINCE2® Foundation Certification Training Pune | PRINCE2® Foundation Certific …
PRINCE2® (Projects IN Controlled Environments) certification is recognized worldwide for its practice-driven approach to project management. PRINCE2® is a Project Management Methodology. The methodology includes the management, control, and organization of a project. Vinsys is conducting PRINCE2® Foundation Certification Training in Pune on 18-19-25 And 26 August 2018. The purpose of the foundation level is to confirm you have enough information and understanding of the PRINCE2® method to be able to
Hyper IgM Foundation Research Grants:
FOR IMMEDIATE RELEASE: February 05, 2018. The Hyper IgM Foundation is proud to announce the availability of seed grant funding for researchers interested in the advancement of a cure for Hyper IgM Syndrome and primary immunodeficiency disorders. The intent of these grants is to accelerate scientific work focused on improving the treatment, quality of life, and long-term outlook for patients with Hyper IgM. Special consideration will be given to well-defined projects
vWIN foundation goes online
Venous World Inter-university Network (vWIN) foundation was created by Sergio Gianesini, Oscar Bottini and Yung Wei Chi, three vein specialists from the University of Ferrara (Italy), Universidad de Buenos Aires (Argentina) and the University of California Davis (USA), respectively. vWIN as three main aims: Scientific research & meetings Humanitarian missions Social and Sport activities promoting public venous & health awareness The first rationale of the foundation is the improvement of the scientific knowledge about the
openAPC Foundation e.V. has become Associate Member at Eclipse Foundation
April, 2011 (Dresden, Germany) Since March 2011, the openAPC Foundation e.V. has become “Associate Member” at the Eclipse Foundation. The openAPC Foundation e.V. in Dresden, Germany is using the Eclipse Public License (EPL) as open source license for free available Advanced Process Control (APC) software solutions. APC software is used to reveal process deviations and to increase process stability, i.e. during production and manufacturing processes. “Right from the start of the
Alpha Foundation Specialists of Florida Expands Foundation Repair Business
Alpha Foundation Specialists of Florida Expands Foundation Repair Business Tallahassee, FL - Local foundation repair contractor company, Alpha Foundation Specialists of Florida, teams up with the international Foundation Supportworks network. Alpha Foundation Specialists, a locally owned and operated foundation repair contractor serving the northern Florida and south Georgia area, is growing. They’ve been selected to take up the Foundation Supportworks (FSI) banner in their area, and have joined this contractor network that
DreamSpring Joins The Symbian Foundation
Gold Coast, Australia, 14 July 2009 — DreamSpring, a specialist in innovative smartphone software, announced its new status as a member of the Symbian Foundation, the creator of an open platform for smartphones. DreamSpring today announced that it has joined the Symbian Foundation, which, together with its ecosystem, is creating the most proven, open and complete mobile software platform. The platform is based on Symbian OS and software assets contributed by