Global B Cell Lymphoma Market and Clinical Pipeline Insight 2022 Report

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Table of Contents

1. Introduction to B Cell Lymphoma
1.1 Outline
1.1.1 Non-Hodgkin’s Lymphoma
1.1.2 Hodgkin’s Lymphoma
1.2 Classification of the B Cell lymphoma
1.2.1 Diffuse Large B Cell Lymphoma
1.2.2 Follicular Lymphoma
1.2.3 Mantle Cell Lymphoma
1.2.4 Burkitt Lymphoma
1.3 Stages of B Cell Lymphoma

2. Role of B Cell Receptor for Lymphoma Development
2.1 Diffuse Large B Cell Lymphoma
2.2 Mantle Cell Lymphoma
2.3 Burkitt Lymphoma

3. Non-Hodgkin Lymphoma Risk Factors
3.1 Overview of Risk Factors
3.1.1 Infections
3.1.2 Weakened Immune System
3.1.3 Exposure to Radiation
3.1.4 Exposure to Chemicals
3.2 Causes of Non-Hodgkin Lymphoma

4. Strategies for B Cell Lymphoma Targeting Therapies
4.1 Current Strategies
4.1.1 Bruton’s Tyrosine Kinase (BTK)
4.1.2 Phosphoinositide 3-Kinase anddelta; (PI3Ks)
4.1.3 Spleen Tyrosine Kinase (SYK)
4.2 Next Generation Strategies for the Vaccine Therapy
4.2.1 Membrane Proteoliposomal Vaccine
4.2.2 Cytotoxic Therapies

5. Diagnosis of B Cell Lymphoma
5.1 Traditional Methods of Detection
5.1.1 Biopsy Method
5.1.2 Flow Cytometry
5.1.3 Molecular Genetic Tests
5.1.4 Positron Emission Tomography (PET) Scan
5.2 New Insights for Diagnosis of B Cell Lymphoma
5.2.1 Genomic Studies in the Diagnosis
5.2.2 Next Generation Sequencing
5.3 Biomarker in B Cell Malignancies
5.3.1 MicroRNA-155
5.3.2 B Cell Markers

6. Approaches for the Treatment B Cell Lymphoma
6.1 Chemotherapy
6.2 Radiation Therapy

7. Targeted Therapy Drugs for B Cell Lymphoma
7.1 Proteasome Inhibitors
7.2 Anti-CD22 Antibody Epratuzumab
7.3 Immunomodulators
7.4 Fostamatinib Disodium (Syk Inhibitor)
7.5 Membrane Target of Rapamycin (mTOR)

8. Global B Cell Lymphoma Market Overview
8.1 Current Scenario
8.2 Prevalence
8.3 B Cell Lymphoma Clinical Pipeline Overview

9. Global B Cell Lymphoma Market Dynamics
9.1 Accelerative Parameters
9.2 Challenges to the Market Growth

10. Global B Cell Lymphoma Market Future Scenario

11. Global B Cell Lymphoma Clinical Pipeline by Company and Phase
11.1 Research
11.2 Preclinical
11.3 Clinical
11.4 Phase-I
11.5 Phase-I/II
11.6 Phase-II
11.7 Phase-II/III
11.8 Phase-III
11.9 Preregistration
11.10 Registered

12. Marketed B Cell Lymphoma Clinical Insight
12.1 Rituximab (MabThera and Rituxan)
12.2 Rituximab Biosimilar (Novex)
12.3 Rituximab Biosimilar (Maball)

13. Competitive Landscape
13.1 Abbott Laboratories
13.2 Biogen Idec
13.3 Celgene Corporation
13.4 Genmab
13.5 Hetero Drugs
13.6 ImmunoGen
13.7 Incyte Corporation
13.8 mAbxience
13.9 Merck
13.10 Millennium Pharmaceuticals
13.11 Ono Pharmaceutical
13.12 Sandoz
13.13 Seattle Genetics
13.14 Xencor

Figure 1-1: Types of B Cell Lymphoma
Figure 1-2: B Cell Lymphoma Stages
Figure 2-1: B Cell Receptor in Diffuse Large B Cell Lymphoma
Figure 2-2: B Cell Receptor Signaling Pathway in Mantle Cell Lymphoma
Figure 3-1: Risk Factors Associated with B Cell Lymphoma
Figure 4-1: Bruton’s Tyrosine Kinase Pathway for Targeting
Figure 4-2: Phosphoinositide 3-Kinase anddelta; as Targeting Therapy
Figure 4-3: Spleen Tyrosine Kinase for Targeting
Figure 5-1: Traditional Methods for Diagnosis of B Cell Lymphoma
Figure 5-2: Noval Techniques for Detection
Figure 6-1: Approaches for the Treatment of B Cell Lymphoma
Figure 8-1: Global - Non-Hodgkin Lymphoma Market (US$ Billion), 2016 - 2022
Figure 8-2: Global - Hodgkin Lymphoma Market (US$ Million), 2016 - 2022
Figure 8-3: Survival Rate of Non-Hodgkin Lymphoma, % (5, 10, 15 Years)
Figure 8-4: Early Stage and Advance Stage Survival Rate, %
Figure 8-5: Estimated Cases of Non-Hodgkin Lymphoma, 100,000 Persons
Figure 8-6: US - B Cell Lymphoma Incidence
Figure 8-7: UK - Diagnosed Cases in Males and Females
Figure 8-8: UK - Mortality Cases in Males and Females
Figure 8-9: India - Incidence Rate in Males and Females
Figure 8-10: Global - B Cell Lymphoma Clinical Pipeline by Phase (%), 2017 till 2022
Figure 8-11: Global -B Cell Lymphoma Clinical Pipeline by Phase (Number), 2017 till 2022
Figure 8-12: Global - Discontinued and Suspended B Cell Lymphoma Drugs in Clinical Pipeline (%), 2017 till 2022
Figure 8-13: Global - Discontinued and Suspended B Cell Lymphoma Drugs in Clinical Pipeline (Number), 2017 till 2022
Figure 9-1: Market Drivers of B cell Lymphoma
Figure 9-2: Challenges to the Growth of the Market

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