Genome Editing Market Size Worth USD 25.58 Billion in 2032 | Emergen Research

The global genome editing market size was USD 6.10 Billion in 2022 and is expected to register a rapid revenue CAGR of 15.3% during the forecast period. The global genome editing market is experiencing substantial growth, driven by a confluence of factors including increased government funding, burgeoning genomic projects, and remarkable advancements in gene editing technologies. The market is witnessing a surge in strategic initiatives by the biotechnology industry, coupled with continuous technological enhancements in gene editing tools, particularly the introduction of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 technology.

Genome editing, a form of gene therapy, enables targeted alterations within the genome of specific cells to treat or prevent genetic conditions. This technique encompasses various modifications such as insertion, deletion, replacement, and alteration of DNA sequences, offering immense potential across diverse organisms including plants, animals, and microorganisms.

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Genome Editing Tools in Agriculture

Agricultural scientists are leveraging genome editing tools to introduce specific trait genes into crop genomes, enhancing characteristics like yield, drought resistance, disease resistance, and nutritional content. These advancements address critical challenges in food security and sustainability.

Leading biotechnology companies are at the forefront of innovation, introducing novel gene editing technologies to meet the growing demand for synthetic genes and support Research & Development (R&D) activities in Genetically Modified Organisms (GMOs). Notable advancements include Corteva Agriscience's CRISPR-based plant breeding innovations aimed at combating corn diseases and enhancing multi-disease resistance.

Addressing Chronic Diseases and Genetic Disorders

The rising prevalence of chronic diseases and genetic disorders underscores the importance of genomics and R&D efforts for therapeutic development. Major initiatives are underway to tackle conditions like Cardiovascular Disease (CVD), cancer, Alzheimer's Disease (AD), and Parkinson's Disease (PD), with companies like bit.bio introducing products for gene knockouts in relevant human cells.

Genome Editing Market Trends

CRISPR-Cas9 Technology and Therapeutic Applications

CRISPR-based genome editing, particularly CRISPR-Cas9, is revolutionizing research in cardiovascular diseases and other medical fields. Companies like CRISPR Therapeutics are exploring CRISPR-based therapies for treating cardiovascular diseases, showcasing the technology's potential in precision medicine and therapeutic development.
Gene delivery using viral vectors has emerged as a powerful tool in developing gene therapies. Viral vector-based therapies have gained regulatory approval for various diseases, contributing to significant advancements in the field.

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Genome Editing Market Restraints

Despite its precision, CRISPR technology can exhibit off-target effects, leading to unintended alterations in the genome. Additionally, stringent regulations governing genetically modified products, driven by ethical concerns and misinformation, pose challenges to market growth.

Genome Editing Market Segment Insights

The CRISPR segment dominates the global genome editing market due to its accuracy, efficiency, and versatility in various applications, including personalized treatments for chronic diseases like cancer. However, the TALEN segment is also poised for steady growth, offering precise genome editing capabilities.

Genome Editing End-Use Insights

Biotechnology and pharmaceutical companies lead in genome editing market share, fueled by the rising prevalence of chronic diseases and the availability of genetic engineering tools. Collaborations and strategic developments further bolster the adoption of genome editing technologies in therapeutic applications.

In conclusion, the global genome editing market is poised for significant growth fueled by technological advancements, strategic initiatives, and increasing applications across diverse industries. Despite challenges such as off-target effects and regulatory constraints, the market's trajectory remains promising, with continued innovation driving therapeutic advancements and addressing pressing healthcare needs.

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Genome Editing Top Companies and Competitive Landscape

The global genome editing market is fairly fragmented, with many large and medium-sized players accounting for majority of market revenue. Major players are deploying various strategies, entering into mergers & acquisitions, strategic agreements & contracts, developing, testing, and introducing more effective genome editing solutions.

• Thermo Fisher Scientific Inc.
• Merck KGaA
• Lonza
• GenScript
• Tecan Trading AG
• PerkinElmer Inc.
• Agilent Technologies, Inc.
• CRISPR Therapeutics
• Editas Medicine
• Cellectis
• Sangamo Therapeutics
• Precision BioSciences
• Intellia Therapeutics, Inc.
• bluebird bio, Inc.
• Creative Biogene
• Synthego
• Beam Therapeutics
• AMSBIO
• Regeneron Pharmaceuticals Inc.
• Mammoth Biosciences, Inc.
• OriGene Technologies, Inc.
• New England Biolabs
• Caribou Biosciences, Inc.
• Inscripta, Inc.
• Integrated DNA Technologies, Inc.
• Horizon Discovery Ltd.
• Takara Bio Inc.
• AstraZeneca
• Recombinetics
• Cibus Inc.,
• Bio-Rad Laboratories, Inc.

Genome Editing Latest Industry News

• On 1 November 2023, AstraZeneca announced the collaboration and investment agreement with Cellectis, a clinical-stage biotechnology company to develop next generation therapeutic areas such as gene therapy and gene editing for treatment of oncology, immunology and rare diseases.

• On 15 February 2022, Intellia Therapeutics, Inc., a major genome editing company that develop curative CRISPR-based therapies and ONK Therapeutics Ltd., an innovative company dedicated to design optimally engineered Natural Killer (NK) cell therapies to cure cancer patients announced the collaboration agreement to advanced allogenic CRISPR-edited NK cell therapies for treatment of patients with cancer.

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Genome Editing Market Segment Analysis

For the purpose of this report, Emergen Research has segmented the global genome editing market on the basis of product and services type, technology, delivery method, application, end-use, and region:

• Product and Services Type Outlook (Revenue, USD Billion; 2019-2032)
o Reagents and Consumables
o Software and Systems
o Services

• Technology Outlook (Revenue, USD Billion; 2019-2032)
o Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
o Transcription Activator-Like Effector Nuclease (TALEN)
o Zinc Finger Nuclease (ZFN)
o Antisense
o Meganucleases
o Others

• Delivery Method Outlook (Revenue, USD Billion; 2019-2032)
o Ex-Vivo
o In-Vivo

• Application Outlook (Revenue, USD Billion; 2019-2032)
o Genetic Engineering
1. Cell Line Engineering
2. Animal Genetic Engineering
3. Plant Genetic Engineering
4. Gene-modification Cell Therapy
5. Others

o Clinical Applications
1. Diagnostics Application
2. Drug Discovery and Development
3. Therapy Development

• End-Use Outlook (Revenue, USD Billion; 2019-2032)
o Biotechnology and Pharmaceutical Companies
o Academic and Research Institutes
o Contract Research Organizations (CROs)
o Hospitals
o Others

• Regional Outlook (Revenue, USD Billion; 2019-2032)
o North America
1. U.S.
2. Canada
3. Mexico
o Europe
1. Germany
2. France
3. UK
4. Italy
5. Spain
6. Benelux
7. Rest of Europe
o Asia Pacific
1. China
2. India
3. Japan
4. South Korea
5. Rest of APAC
o Latin America
1. Brazil
2. Rest of LATAM
o Middle East & Africa
1. Saudi Arabia
2. UAE
3. South Africa
4. Turkey
5. Rest of Middle East & Africa

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